Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Wolfgang Staffen"'
Autor:
Diana M. Bessa de Sousa, Rodolphe Poupardin, Saul A. Villeda, Adam B. Schroer, Thomas Fröhlich, Vanessa Frey, Wolfgang Staffen, Heike Mrowetz, Barbara Altendorfer, Michael S. Unger, Bernhard Iglseder, Bernhard Paulweber, Eugen Trinka, Janne Cadamuro, Martin Drerup, Katharina Schallmoser, Ludwig Aigner, Kathrin M. Kniewallner
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Introduction: Alzheimer’s disease (AD) and aging are associated with platelet hyperactivity. However, the mechanisms underlying abnormal platelet function in AD and aging are yet poorly understood.Methods: To explore the molecular profile of AD and
Externí odkaz:
https://doaj.org/article/636238625d2e475984b6becd06a2383c
Autor:
Petr Novak, Reinhold Schmidt, Eva Kontsekova, Branislav Kovacech, Tomas Smolek, Stanislav Katina, Lubica Fialova, Michal Prcina, Vojtech Parrak, Peter Dal-Bianco, Martin Brunner, Wolfgang Staffen, Michael Rainer, Matej Ondrus, Stefan Ropele, Miroslav Smisek, Roman Sivak, Norbert Zilka, Bengt Winblad, Michal Novak
Publikováno v:
Alzheimer’s Research & Therapy, Vol 10, Iss 1, Pp 1-16 (2018)
Abstract Background Neurofibrillary pathology composed of tau protein is closely correlated with severity and phenotype of cognitive impairment in patients with Alzheimer’s disease and non-Alzheimer’s tauopathies. Targeting pathological tau prote
Externí odkaz:
https://doaj.org/article/0a507430e9e248e6b42f67da7fb4aa06
Autor:
Fabian Schwimmbeck, Wolfgang Staffen, Christopher Höhn, Fabio Rossini, Nora Renz, Markus Lobendanz, Peter Reichenpfader, Bernhard Iglseder, Ludwig Aigner, Eugen Trinka, Yvonne Höller
Publikováno v:
Brain Sciences, Vol 11, Iss 5, p 547 (2021)
Montelukast is a well-established antiasthmatic drug with little side effects. It is a leukotriene receptor antagonist and recent research suggests cognitive benefits from its anti-inflammatory actions on the central nervous system. However, changes
Externí odkaz:
https://doaj.org/article/ae0bd07e3286425980cb9e37fde22876
Autor:
Yvonne Höller, Arne C. Bathke, Andreas Uhl, Nicolas Strobl, Adelheid Lang, Jürgen Bergmann, Raffaele Nardone, Fabio Rossini, Harald Zauner, Margarita Kirschner, Amirhossein Jahanbekam, Eugen Trinka, Wolfgang Staffen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
Single photon emission computed tomography (SPECT) and Electroencephalography (EEG) have become established tools in routine diagnostics of dementia. We aimed to increase the diagnostic power by combining quantitative markers from SPECT and EEG for d
Externí odkaz:
https://doaj.org/article/059c01e57e994ddcbb1e9f369d6b1c7d
Autor:
Yvonne Höller, Kevin Butz, Aljoscha Thomschewski, Elisabeth Schmid, Andreas Uhl, Arne C. Bathke, Georg Zimmermann, Santino O. Tomasi, Raffaele Nardone, Wolfgang Staffen, Peter Höller, Markus Leitinger, Julia Höfler, Gudrun Kalss, Alexandra C. Taylor, Giorgi Kuchukhidze, Eugen Trinka
Publikováno v:
Frontiers in Human Neuroscience, Vol 11 (2017)
Alterations of interaction (connectivity) of the EEG reflect pathological processes in patients with neurologic disorders. Nevertheless, it is questionable whether these patterns are reliable over time in different measures of interaction and whether
Externí odkaz:
https://doaj.org/article/1fb14916b22948f599d24634f755927c
Autor:
Wolfgang Staffen, Martin Kronbichler, Eugen Trinka, I. Spindler, Fabio Rossini, Harald Zauner, Stefan Golaszewski, Jürgen Bergmann
Publikováno v:
Current Alzheimer Research. 16:843-851
Background:Growing evidence suggests that pathological processes leading to Alzheimer’s disease occurs gradually and begins to develop decades before the earliest clinical symptoms occur. The use of biomarkers has been proposed to detect evidence o
Autor:
Fabio Rossini, Peter Reichenpfader, Bernhard Iglseder, Ludwig Aigner, Christopher Höhn, Yvonne Höller, Nora Renz, Fabian Schwimmbeck, Wolfgang Staffen, Eugen Trinka, Markus Lobendanz
Publikováno v:
Brain Sciences; Volume 11; Issue 5; Pages: 547
Brain Sciences
Brain Sciences, Vol 11, Iss 547, p 547 (2021)
Brain Sciences
Brain Sciences, Vol 11, Iss 547, p 547 (2021)
Montelukast is a well-established antiasthmatic drug with little side effects. It is a leukotriene receptor antagonist and recent research suggests cognitive benefits from its anti-inflammatory actions on the central nervous system. However, changes
Autor:
Wolfgang Staffen, Giorgi Kuchukhidze, Andreas Uhl, Eugen Trinka, Marlene Derner, Elisabeth Schmid, Raffaele Nardone, Arne C. Bathke, Christoph D. Hofer, Yvonne Höller, Kevin Butz, Markus Leitinger, Fabian Schwimmbeck, Aljoscha Thomschewski, Jürgen Fell
Publikováno v:
Computational Intelligence and Neuroscience, Vol 2020 (2020)
Computational Intelligence and Neuroscience
Computational Intelligence and Neuroscience
Cognitive decline is a severe concern of patients with mild cognitive impairment. Also, in patients with temporal lobe epilepsy, memory problems are a frequently encountered problem with potential progression. On the background of a unifying hypothes
Autor:
Rostislav Skrabana, Vojtech Parrak, Zuzana Vince-Kazmerova, Stefan Ropele, Norbert Zilka, Michal Prcina, Michael Rainer, Lubica Fialova, Eva Kontsekova, Branislav Kovacech, Petr Novak, Miroslav Smisek, Roman Sivak, Peter Dal-Bianco, Stanislav Katina, Matej Ondrus, Wolfgang Staffen, Michal Novak, Martin Brunner, Reinhold Schmidt, Bengt Winblad
Publikováno v:
The Lancet Neurology. 16:123-134
Summary Background Neurofibrillary pathology composed of tau protein is a main correlate of cognitive impairment in patients with Alzheimer's disease. Immunotherapy targeting pathological tau proteins is therefore a promising strategy for disease-mod
Autor:
Roland Beisteiner, Stefan Golaszewski, Alexander Geißler, Christian Siedentopf, Janpeter Nickel, Wolfgang Staffen, Michael Verius, N. Klinger, Markus Aichhorn, Martin Kronbichler, Thomas Foki, Moritz C. Wurnig, Stephan Felber, Ilse Höllinger, Florian Ph. S. Fischmeister, Jakob Rath, Florian Koppelstaetter, Eduard Auff, Rüdiger J. Seitz
Publikováno v:
Human Brain Mapping. 37:2151-2160
This study provides first data about the spatial variability of fMRI sensorimotor localizations when investigating the same subjects at different fMRI sites. Results are comparable to a previous patient study. We found a median between-site variabili