Výsledky vyhledávání - "Wolfgang Schwabe"

Dissertation/ Thesis

Continuity and Change in the Zhuangzi and the Xicizhuan

Autor: Wolfgang Schwabe, 施維禮

95
The question how to attain continuity in change goes beyond specific disciplines or individual cultures. This thesis discusses the relationship between continuity and change in two philosophical works in ancient China, the Zhuangzi 莊子and

Externí odkaz: http://ndltd.ncl.edu.tw/handle/57318293317587428580

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Transferring a Quantitative Molecular Diagnostic Test to Multiple Real-Time Quantitative PCR Platforms

Autor: Wolfgang Schwabe, Xingmin Li, Ugur Sahin, Claudia Gürtler, Heike Steinhäuser, Mark Laible, Shujin Liu, Kornelia Schlombs

Publikováno v: The Journal of Molecular Diagnostics. 20:398-414

Quantitative gene expression assays are increasingly used for diagnosis and research, but are often restricted to specific instrumentation. We propose a robust technical and statistical framework that enables transferring of established real-time qua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7930549a174ab176ab05b5cf125820
https://doi.org/10.1016/j.jmoldx.2018.02.004

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Need for nursing care support in cancer patients: Registry-linkage study in Germany

Autor: Jacob Spallek, Jürgen Breckenkamp, Klaus Kraywinkel, Wolfgang Schwabe, Volker Krieg, Wolfgang Greiner, Oliver Damm, Oliver Razum

Publikováno v: South Eastern European Journal of Public Health (SEEJPH)
South Eastern European Journal of Public Health (2018)
South Eastern European Journal of Public Health, Vol 11, Iss 0 (2018)

Aim: In Germany, very little is known about the need for assistance and nursing care support among cancer patients after hospitalization. The aim of this study was to describe nursing care support for cancer patients and to analyse whether these pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2a2a4ea3dbcc8b617f5e8c0e63fb4e

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Immunohistochemical Analysis of Thymidylate Synthase, Thymidine Phosphorylase, and Dihydropyrimidine Dehydrogenase in Rectal Cancer (cUICC II/III)

Autor: Christiane Jakob, Daniela E. Aust, Heinz Becker, W. Meyer, Gustavo Baretton, Peter Häusler, Torsten Liersch, Wolfgang Schwabe

Publikováno v: American Journal of Surgical Pathology. 29:1304-1309

In locally advanced rectal cancer, neoadjuvant 5-fluorouracil (5-FU)-based long-term chemoradiotherapy leads to marked tumor reduction and decrease of local recurrence rate. Thymidylate synthase (TS), thymidine phosphorylase (TP), and dihydropyrimidi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa33556f9f7af2dcbea19034563b5da
https://doi.org/10.1097/01.pas.0000170346.55304.88

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High-level mRNA quantification of proliferation marker pKi-67 is correlated with favorable prognosis in colorectal carcinoma

Autor: Jian Liu, Rainer Broll, M. Duchrow, Peter Häusler, Hans-Peter Bruch, Wolfgang Schwabe, U. Windhövel, Thomas Ihmann, D. Behnke

Publikováno v: Journal of Cancer Research and Clinical Oncology. 130:749-756

The present study retrospectively examines the expression of pKi-67 mRNA and protein in colorectal carcinoma and their correlation to the outcome of patients.Immunohistochemistry and quantitative RT-PCR were used to analyze the expression of pKi-67 i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9502bacd67818b7d42663ebd542a93ca
https://doi.org/10.1007/s00432-004-0612-5

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Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer

Autor: W. Meyer, Daniela E. Aust, Peter Häusler, Wolfgang Schwabe, Heinz Becker, Christiane Jakob, Gustavo Baretton, Torsten Liersch

Publikováno v: The Journal of Pathology. 204:562-568

Pre-operative 5-fluorouracil (5-FU)-based chemoradiotherapy in locally advanced rectal cancer (UICC-II/III) may significantly reduce local tumour mass. Response to pre-operative treatment, however, varies significantly. Thymidylate synthase (TS), thy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3f1828fb876fedfa82b9ad3b34f5b06
https://doi.org/10.1002/path.1663

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Circadian variation of dihydropyrimidine dehydrogenase mRNA expression in leukocytes and serum cortisol levels in patients with advanced gastrointestinal carcinomas compared to healthy controls

Autor: Joachim H. Clement, M. Raida, Peter Häusler, Klaus Höffken, Wolfgang Schwabe, K. O. Kliche, D. Behnke

Publikováno v: Journal of Cancer Research and Clinical Oncology. 128:96-102

Purpose: The activity of dihydropyrimidine dehydrogenase (DPD) – the rate-limiting enzyme in fluorouracil (5-FU) catabolism – has been reported to vary according to the time of day. On the basis of this data, so-called chronomodulated chemotherap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da42fca20544a5501d725bc629265523
https://doi.org/10.1007/s00432-001-0309-y

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Evaluation of 5-Fluorouracil Pharmacokinetics in Cancer Patients with a c.1905+1G > A Mutation in DPYD by Means of a Bayesian Limited Sampling Strategy

Autor: Kati Jabschinsky, Andreas Schalhorn, Peter Häusler, J. G. Maring, André B.P. van Kuilenburg, Johannes H. Proost, Michael W.T. Tanck, Wolfgang Schwabe, Christoph Terborg, D. Behnke

Publikováno v: Clinical Pharmacokinetics, 51(3), 163-174. Springer International Publishing AG
Clinical pharmacokinetics, 51(3), 163-174. Adis International Ltd

Background and Objective: Dihydropyrimidine dehydrogenase (DPD) is the initial enzyme in the catabolism of 5-fluorouracil (5FU) and DPD deficiency is an important pharmacogenetic syndrome. So far, only very limited information is available regarding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6edf7e5489cef7ab5dd6d16a2be996
https://research.rug.nl/en/publications/e4fa091b-9280-438e-bdfd-8b277d5c31c7

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Pharmacokinetics of 5-fluorouracil in patients heterozygous for the IVS14+1GA mutation in the dihydropyrimidine dehydrogenase gene

Autor: Wolfgang Schwabe, K. Jabschinsky, D. Behnke, C. Terborg, Peter Häusler, J. G. Maring, A. B. P. Van Kuilenburg, H. Schmalenberg, A. Schalhorn

Publikováno v: Nucleosides, nucleotides & nucleic acids, 27(6), 692-698. Marcel Dekker Inc.

5-Fluorouracil (5FU) and capecitabine are two of the most frequently prescribed chemotherapeutic drugs for the treatment of patients with cancer. Administration of test doses of 5FU to eight patients heterozygous for the IVS14+1G > A mutation and fiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5348544dd49b5b62b2c6ce13e9c77049
https://pubmed.ncbi.nlm.nih.gov/18600527

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