Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wolfgang Schamel"'
Autor:
Jamal Alzubi, Viviane Dettmer-Monaco, Johannes Kuehle, Niko Thorausch, Maximilian Seidl, Sanaz Taromi, Wolfgang Schamel, Robert Zeiser, Hinrich Abken, Toni Cathomen, Philipp Wolf
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 226-235 (2020)
While chimeric antigen receptor (CAR) T cell immunotherapy targeting CD19 has shown remarkable success in patients with lymphoid malignancies, the potency of CAR T cells in solid tumors is low so far. To improve the efficacy of CAR T cells targeting
Externí odkaz:
https://doaj.org/article/da969265138c4086a127a5b413c0ca52
Autor:
Andrea Schmidts, Maria Ormhøj, Bryan D. Choi, Allison O. Taylor, Amanda A. Bouffard, Irene Scarfò, Rebecca C. Larson, Matthew J. Frigault, Kathleen Gallagher, Ana P. Castano, Lauren S. Riley, Maria L. Cabral, Angela C. Boroughs, Rubí M.-H. Velasco Cárdenas, Wolfgang Schamel, Jing Zhou, Sean Mackay, Yu-Tzu Tai, Kenneth C. Anderson, Marcela V. Maus
Publikováno v:
Blood Advances, Vol 3, Iss 21, Pp 3248-3260 (2019)
Abstract: Chimeric antigen receptor (CAR) T cells (CARTs) have shown tremendous potential for the treatment of certain B-cell malignancies, including patients with relapsed/refractory multiple myeloma (MM). Targeting the B-cell maturation antigen (BC
Externí odkaz:
https://doaj.org/article/744190eefb7f4eac95dde4520a55224b
Autor:
O. Sascha Yousefi, Maximilian Hörner, Maximilian Wess, Vincent Idstein, Wilfried Weber, Wolfgang Schamel
Publikováno v:
Bio-Protocol, Vol 10, Iss 5 (2020)
T cells are one major cell type of the immune system that use their T cell antigen receptor (TCR) to bind and respond to foreign molecules derived from pathogens. The ligand-TCR interaction half-lives determine stimulation outcome. Until recently, sc
Externí odkaz:
https://doaj.org/article/570978d322d0438cac185007171e3556
Publikováno v:
Bio-Protocol, Vol 10, Iss 5 (2020)
In the field of extracellular optogenetics, photoreceptors are applied outside of cells to obtain systems with a desired functionality. Among the diverse applied photoreceptors, phytochromes are the only ones that can be actively and reversibly switc
Externí odkaz:
https://doaj.org/article/9384861756e04d268228f37099a8b27b
Autor:
Chengsong Yan, Lin Zheng, Shutan Jiang, Haochen Yang, Jun Guo, Lu-yi Jiang, Tongzhou Li, Haosong Zhang, Yibing Bai, Yu Lou, Qi Zhang, Tingbo Liang, Wolfgang Schamel, Haopeng Wang, Weiwei Yang, Guangchuan Wang, Zheng-jiang Zhu, Bao-Liang Song, Chenqi Xu
Publikováno v:
Cancer Cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::276050af6639d54a218ab1a4cb4cad6a
https://doi.org/10.1016/j.ccell.2023.04.016
https://doi.org/10.1016/j.ccell.2023.04.016
Autor:
Susana Minguet, Rubí Velasco Cárdenas, Simon Brandl, Emilia Schlaak, Annabelle Buschky, Timo Peters, Fabian Beier, Bryan Serrels, Sanaz Taromi, Katrin Raute, Simon Hauri, Matthias Gstaiger, Silke Lassman, Johannes Huppa, Melanie Boerries, Geoffroy Andrieux, Bertram Bengsch, Wolfgang Schamel
Current FDA-approved CAR T cells harbour the TCR-derived ζ chain as intracellular activation domain. The contribution of the other chains of the TCR complex, namely CD3δ, CD3ε, and CD3γ in a CAR format remains unknown. Here, we have systematicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ec2eee5a3c1138410063f621ef7dade
https://doi.org/10.21203/rs.3.rs-2378631/v1
https://doi.org/10.21203/rs.3.rs-2378631/v1
Autor:
Anna-Maria Schaffer, Gina J. Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Babrak, Laurenz A. Herr, Marta Rizzi, Enkelejda Miho, Wolfgang Schamel, Susana Minguet
The ratio between Igκ and Igλ light chain (LC)-expressing B cells varies considerably between species. We recently identified Kinase D-interacting substrate of 220 kDa (Kidins220) as an interaction partner of the BCR. In vivo ablation of Kidins220
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41426d5ee8e3c5300b177840acf0f420
https://doi.org/10.1101/2022.04.04.486937
https://doi.org/10.1101/2022.04.04.486937