Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Wolfgang Poelchen"'
Autor:
Anna Hårdemark, Peter Illes, Björn Johansson, Wolfgang Poelchen, Russell D. Brown, Cecilia Lövdahl, Zsuzsanna Wiesenfeld-Hallin, Catarina Johansson, Bertil B. Fredholm, Rosa M. Escorihuela, Nancy R. Zahniser, Samuel Gebre-Medhin, Anna Ollerstam, Lihong Diao, Shinichi Tokuno, Alberto Fernández-Teruel, Susan A. Masino, Peter Thorén, Eric Herlenius, Thomas V. Dunwiddie, Gunnar Schulte, Ole Skøtt, Linda Halldner, Xiao-Jun Xu, Hilchen Sommerschild, Lydia Giménez-Llort, Milos Pekny, A. Erik G. Persson, Guro Valen
Publikováno v:
Drug Development Research. 58:350-353
The second coding exon of the adenosine A, receptor gene was eliminated by homologous recombination. The phenotype of mice (mixed C57B6/129OlaHsd background) was studied, using siblings from matings of heterozygous mice. Among the offspring the ratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e7d8a6c6ad38432307538dfb0ac47f4
https://doi.org/10.1002/ddr.10170
https://doi.org/10.1002/ddr.10170
Autor:
William R. Proctor, Robert O. Messing, Jeanne M. Wehner, Thomas V. Dunwiddie, Barbara J. Bowers, Wolfgang Poelchen
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:264-270
Ethanol intoxication results partly from actions of ethanol at specific ligand-gated ion channels. One such channel is the GABA A receptor complex, although ethanol9s effects on GABA A receptors are variable. For example, we found that hippocampal ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da0cd8b14aa04e5e5b2bb272a49adf04
https://doi.org/10.1124/jpet.102.045450
https://doi.org/10.1124/jpet.102.045450
Autor:
Lydia Giménez-Llort, Rosa M. Escorihuela, Linda Halldner, Christer Betsholtz, Zsuzsanna Wiesenfeld-Hallin, Anna Hårdemark, Alberto Fernández-Teruel, Eric Herlenius, Thomas V. Dunwiddie, Xiao-Jun Xu, Susan A. Masino, Wolfgang Poelchen, Bertil B. Fredholm, Björn Johansson
Publikováno v:
Proceedings of the National Academy of Sciences. 98:9407-9412
Caffeine is believed to act by blocking adenosine A1and A2Areceptors (A1R, A2AR), indicating that some A1receptors are tonically activated. We generated mice with a targeted disruption of the second coding exon of the A1R (A1R−/−). These animals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::074802b87c789f939dc537ff8ed63e30
https://doi.org/10.1073/pnas.161292398
https://doi.org/10.1073/pnas.161292398
Publikováno v:
Neurochemistry International. 39:51-58
Intracellular recordings were made in pontine slice preparations of the rat brain containing the locus coeruleus (LC). Ethanol at 100 mM, but not at 10 or 30 mM inhibited depolarizing responses to pressure-applied N-methyl-D-aspartate (NMDA) in LC ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbaeb36e098c1c544c3a47d24b41902
https://doi.org/10.1016/s0197-0186(01)00007-9
https://doi.org/10.1016/s0197-0186(01)00007-9
Publikováno v:
Neuroscience. 102:593-602
Intracellular recordings were made in a mid-pontine slice preparation of the rat brain containing the nucleus locus coeruleus. Focal electrical stimulation evoked biphasic synaptic potentials consisting of early depolarizing (d.p.s.p.) and late hyper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a16dacf777464e356ced4843b31ac5
https://doi.org/10.1016/s0306-4522(00)00529-7
https://doi.org/10.1016/s0306-4522(00)00529-7
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 362:568-576
The effect and mode of action of ethanol on N-methyl-D-aspartate (NMDA) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors of rat cortical neurons in primary culture were compared by means of the patch-clamp technique. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a2b81e0faa9198ff4d4490fbafc634
https://doi.org/10.1007/s002100000262
https://doi.org/10.1007/s002100000262
Autor:
Peter Scheibler, K. Mühlberg, Peter Illes, Kerstin Wirkner, László Köles, Wolfgang Poelchen, Clemens Allgaier
Publikováno v:
Neurochemistry International. 35:153-162
Ethanol is a potent inhibitor of the N-methyl-D-aspartate (NMDA)-receptor subtype of glutamate receptor in a number of brain areas. The mechanism of ethanol action has been investigated by means of patch-clamp recording of ionic currents and fura-2 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d062e67b3fe8f56194f521ff1920bf78
https://doi.org/10.1016/s0197-0186(99)00057-1
https://doi.org/10.1016/s0197-0186(99)00057-1
Publikováno v:
Brain Research. 800:170-173
Intracellular recordings were made in a midbrain slice preparation of the rat brain containing the ventral tegmental area (VTA). Dopaminergic principal cells were identified by their electrophysiological properties and their hyperpolarizing responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f081c27df66c65e4b44e075eaeaaa8d
https://doi.org/10.1016/s0006-8993(98)00521-6
https://doi.org/10.1016/s0006-8993(98)00521-6
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 357:299-308
Intracellular recordings were made in a pontine slice preparation of the rat brain containing the nucleus locus coeruleus (LC). In a first series of experiments, various parameters of spontaneous action potentials were evaluated. It turned out that e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7317fefaf6183511c913d2fce592747
https://doi.org/10.1007/pl00005171
https://doi.org/10.1007/pl00005171
Publikováno v:
British Journal of Pharmacology. 122:423-430
1 Intracellular recordings were made in a pontine slice preparation of the rat brain containing the nucleus locus coeruleus (LC). The pressure application of α,β-methylene ATP (α,β-meATP) caused reproducible depolarizations which were depressed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af1ac9ffb3900214da8ec591719473d
https://doi.org/10.1038/sj.bjp.0701386
https://doi.org/10.1038/sj.bjp.0701386