Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Wolfgang Paster"'
Autor:
Carolin Gerke, Liane Bauersfeld, Ivo Schirmeister, Chiara Noemi-Marie Mireisz, Valerie Oberhardt, Lea Mery, Di Wu, Christopher Sebastian Jürges, Robbert M Spaapen, Claudio Mussolino, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Lars Dölken, Wolfgang Paster, Florian Erhard, Maike Hofmann, Andreas Schlosser, Hartmut Hengel, Frank Momburg, Anne Halenius
Publikováno v:
eLife, Vol 13 (2024)
Human leucocyte antigen class I (HLA-I) molecules play a central role for both NK and T-cell responses that prevent serious human cytomegalovirus (HCMV) disease. To create opportunities for viral spread, several HCMV-encoded immunoevasins employ dive
Externí odkaz:
https://doaj.org/article/c867fd290b5f4af9870c2dc3f63a87b4
Autor:
Sabine Tischer-Zimmermann, Elisabeth Salzer, Tamires Bitencourt, Nelli Frank, Christine Hoffmann-Freimüller, Julia Stemberger, Britta Maecker-Kolhoff, Rainer Blasczyk, Volker Witt, Gerhard Fritsch, Wolfgang Paster, Thomas Lion, Britta Eiz-Vesper, René Geyeregger
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAspergillus fumigatus (Asp) infections constitute a major cause of morbidity and mortality in patients following allogeneic hematopoietic stem cell transplantation (HSCT). In the context of insufficient host immunity, antifungal drugs sho
Externí odkaz:
https://doaj.org/article/e7579928abb04b849c28a29c88411a08
Autor:
Katharina Radakovics, Claire Battin, Judith Leitner, Sabine Geiselhart, Wolfgang Paster, Johannes Stöckl, Karin Hoffmann-Sommergruber, Peter Steinberger
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Toll-like receptors (TLRs) are primary pattern recognition receptors (PRRs), which recognize conserved microbial components. They play important roles in innate immunity but also in the initiation of adaptive immune responses. Impurities containing T
Externí odkaz:
https://doaj.org/article/170cbda73b0842d78411fb0c103cf73e
Autor:
Romana Klasinc, Claire Battin, Wolfgang Paster, Michael Reiter, Philipp Schatzlmaier, Peter Rhein, Andreas Spittler, Peter Steinberger, Hannes Stockinger
Publikováno v:
Microorganisms, Vol 10, Iss 12, p 2489 (2022)
Chlamydia trachomatis (Ct) is the most common cause of genital tract infections as well as preventable blindness worldwide. Pattern recognition receptors such as toll-like receptors (TLRs) represent the initial step in recognizing pathogenic microorg
Externí odkaz:
https://doaj.org/article/d9e37f4fc2744628baf61f0b2ed80845
Autor:
Claire Battin, Annika De Sousa Linhares, Wolfgang Paster, David E. Isenman, Markus Wahrmann, Judith Leitner, Gerhard J. Zlabinger, Peter Steinberger, Johannes Hofer
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Complement split products (CSPs), such as the fragments C4d and C3d, which are generated as a consequence of complement regulatory processes, are established markers for disease activity in autoimmunity or antibody-mediated graft rejection. Since imm
Externí odkaz:
https://doaj.org/article/89a13f69e21d4155843fc2e1f9758be8
Autor:
Claire Battin, Annika Hennig, Patrick Mayrhofer, Renate Kunert, Gerhard J Zlabinger, Peter Steinberger, Wolfgang Paster
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178220 (2017)
Sensing of pathogens by innate immune cells is essential for the initiation of appropriate immune responses. Toll-like receptors (TLRs), which are highly sensitive for various structurally and evolutionary conserved molecules derived from microbes ha
Externí odkaz:
https://doaj.org/article/200cb942bd7b4017a19164d20cd20260
Autor:
Francesca Finotello, Markus Ausserhofer, Geyeregger René, Dietmar Rieder, Georgios Fotakis, Wolfgang Paster, Zlatko Trajanoski
Publikováno v:
Bioinformatics
Summary Somatic mutations and gene fusions can produce immunogenic neoantigens mediating anticancer immune responses. However, their computational prediction from sequencing data requires complex computational workflows to identify tumor-specific abe
Autor:
Elena Rainero, Cristina Cianflone, Paolo Ettore Porporato, Federica Chianale, Valeria Malacarne, Valentina Bettio, Elisa Ruffo, Michele Ferrara, Fabio Benecchia, Daniela Capello, Wolfgang Paster, Irene Locatelli, Alessandra Bertoni, Nicoletta Filigheddu, Fabiola Sinigaglia, Jim C Norman, Gianluca Baldanzi, Andrea Graziani
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e97144 (2014)
Diacylglycerol kinase α (DGKα), by phosphorylating diacylglycerol into phosphatidic acid, provides a key signal driving cell migration and matrix invasion. We previously demonstrated that in epithelial cells activation of DGKα activity promotes cy
Externí odkaz:
https://doaj.org/article/66b47552bef645f1b45c28e4c5ca2e51
Autor:
Benedikt Agerer, Venugopal Gudipati, Maximilian Koblischke, Doris Trapin, Elisabeth Puchhammer-Stöckl, Thomas Penz, Mark J. Smyth, S. Wenda, Wolfgang Weninger, Jakob-Wendelin Genger, Winfried F. Pickl, Vanessa Mühlgrabner, Luis F Montano-Gutierrez, Stephan W. Aberle, Johannes B. Huppa, Ingrid Fae, Marianne Graninger, Marianna Traugott, Franz Allerberger, Matthias Farlik, Gottfried Fischer, Erich Pawelka, René Geyeregger, Hannes Stockinger, Florian Halbritter, Rudolf Valenta, Pia Gattinger, Lukas Endler, Wolfgang Hoepler, Anna-Maria Husa, Christoph Bock, Wolfgang Paster, Lisa Ellen Shaw, Judith H. Aberle, Alexandra Popa, David M. Florian, Volker Thiel, Daniele Barreca, Alexander Zoufaly, Alexander Lercher, Gernot Walder, Andreas Bergthaler, Ricard Torralba-Gombau
Publikováno v:
Science Immunology
CD8+ T cell immunity to SARS-CoV-2 has been implicated in COVID-19 severity and virus control. Here, we identified nonsynonymous mutations in MHC-I-restricted CD8+ T cell epitopes after deep sequencing of 747 SARS-CoV-2 virus isolates. Mutant peptide
Autor:
Claire Battin, Wolfgang Paster, Karin Hoffmann-Sommergruber, Peter Steinberger, Tonya J. Webb, Piotr Humeniuk, Sabine Geiselhart
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
Scientific Reports
Scientific Reports
Invariant natural killer T (iNKT) cells are a specialized subset of T cells contributing to both, the innate and adaptive immune responses. In contrast to conventional T lymphocytes they recognize lipid antigens. The aim of the project is to establis