Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Wolfgang Oertel"'
Autor:
Sara Cannizzo, Vinciane Quoidbach, Paola Giunti, Wolfgang Oertel, Gregory Pastores, Maja Relja, Giuseppe Turchetti
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract One of the most relevant challenges for healthcare providers during the COVID– 19 pandemic has been assuring the continuity of care to patients with complex health needs such as people living with rare diseases (RDs). The COVID–19 pandem
Externí odkaz:
https://doaj.org/article/6eeae50920484079bba0bb14a87b1646
Autor:
Eric Yu, Lynne Krohn, Jennifer A. Ruskey, Farnaz Asayesh, Dan Spiegelman, Zalak Shah, Ruth Chia, Isabelle Arnulf, Michele T. M. Hu, Jacques Y. Montplaisir, Jean‐François Gagnon, Alex Desautels, Yves Dauvilliers, Gian Luigi Gigli, Mariarosaria Valente, Francesco Janes, Andrea Bernardini, Birgit Högl, Ambra Stefani, Abubaker Ibrahim, Anna Heidbreder, Karel Sonka, Petr Dusek, David Kemlink, Wolfgang Oertel, Annette Janzen, Giuseppe Plazzi, Elena Antelmi, Michela Figorilli, Monica Puligheddu, Brit Mollenhauer, Claudia Trenkwalder, Friederike Sixel‐Döring, Valérie Cochen De Cock, Luigi Ferini‐Strambi, Femke Dijkstra, Mineke Viaene, Beatriz Abril, Bradley F. Boeve, Guy A. Rouleau, Ronald B. Postuma, The International LBD Genomics Consortium, Sonja W. Scholz, Ziv Gan‐Or
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 9, Pp 1682-1687 (2023)
Abstract Synucleinopathies‐related disorders such as Lewy body dementia (LBD) and isolated/idiopathic REM sleep behavior disorder (iRBD) have been associated with neuroinflammation. In this study, we examined whether the human leukocyte antigen (HL
Externí odkaz:
https://doaj.org/article/07b906c4b8104604a171951f2e8d5b33
Autor:
Lynne Krohn, Karl Heilbron, Cornelis Blauwendraat, Regina H. Reynolds, Eric Yu, Konstantin Senkevich, Uladzislau Rudakou, Mehrdad A. Estiar, Emil K. Gustavsson, Kajsa Brolin, Jennifer A. Ruskey, Kathryn Freeman, Farnaz Asayesh, Ruth Chia, Isabelle Arnulf, Michele T. M. Hu, Jacques Y. Montplaisir, Jean-François Gagnon, Alex Desautels, Yves Dauvilliers, Gian Luigi Gigli, Mariarosaria Valente, Francesco Janes, Andrea Bernardini, Birgit Högl, Ambra Stefani, Abubaker Ibrahim, Karel Šonka, David Kemlink, Wolfgang Oertel, Annette Janzen, Giuseppe Plazzi, Francesco Biscarini, Elena Antelmi, Michela Figorilli, Monica Puligheddu, Brit Mollenhauer, Claudia Trenkwalder, Friederike Sixel-Döring, Valérie Cochen De Cock, Christelle Charley Monaca, Anna Heidbreder, Luigi Ferini-Strambi, Femke Dijkstra, Mineke Viaene, Beatriz Abril, Bradley F. Boeve, andMe Research Team, Sonja W. Scholz, Mina Ryten, Sara Bandres-Ciga, Alastair Noyce, Paul Cannon, Lasse Pihlstrøm, Mike A. Nalls, Andrew B. Singleton, Guy A. Rouleau, Ronald B. Postuma, Ziv Gan-Or
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
REM-sleep behavior disorder often precedes Parkinson’s disease or dementia. Here, the authors perform a genome-wide association study for REM-sleep behavior disorder, and discover how it potentially affects gene expression in the brain.
Externí odkaz:
https://doaj.org/article/59eca1d6c47b4c98aed465f4c7a60228
Autor:
Leonie Lampe, Sebastian Niehaus, Hans-Jürgen Huppertz, Alberto Merola, Janis Reinelt, Karsten Mueller, Sarah Anderl-Straub, Klaus Fassbender, Klaus Fliessbach, Holger Jahn, Johannes Kornhuber, Martin Lauer, Johannes Prudlo, Anja Schneider, Matthis Synofzik, Adrian Danek, Janine Diehl-Schmid, Markus Otto, FTLD-Consortium Germany, Arno Villringer, Karl Egger, Elke Hattingen, Rüdiger Hilker-Roggendorf, Alfons Schnitzler, Martin Südmeyer, Wolfgang Oertel, German Atypical Parkinson Consortium Study Group, Jan Kassubek, Günter Höglinger, Matthias L. Schroeter
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Importance The entry of artificial intelligence into medicine is pending. Several methods have been used for the predictions of structured neuroimaging data, yet nobody compared them in this context. Objective Multi-class prediction is key f
Externí odkaz:
https://doaj.org/article/432717d710b541bc9487a725d27bb8d9
Autor:
Judit Simon, Patrice Boyer, Jose M. Caldas-de-Almeida, Martin Knapp, Paul McCrone, Philip Gorwood, Wolfgang Oertel, Celso Arango, Janet Treasure, Allan H. Young, Frederic Destrebecq, Vinciane Quoidbach
Publikováno v:
European Psychiatry, Vol 66 (2023)
One in eight individuals worldwide lives with a mental health disorder. For many European countries, the prevalence is even higher, with one in four people reporting mental health problems [1]. Three-quarters of all mental health disorders develop be
Externí odkaz:
https://doaj.org/article/4e4cc161639647639d117aa6a7f58838
Autor:
Xianhua Han, Ping Wu, Ian Alberts, Hucheng Zhou, Huan Yu, Panagiotis Bargiotas, Igor Yakushev, Jian Wang, Guenter Höglinger, Stefan Förster, Claudio Bassetti, Wolfgang Oertel, Markus Schwaiger, Sung-Cheng Huang, Paul Cumming, Axel Rominger, Jiehui Jiang, Chuantao Zuo, Kuangyu Shi
Publikováno v:
NeuroImage: Clinical, Vol 27, Iss , Pp 102294- (2020)
Objective: Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal stage of synucleinopathies such as Parkinson’s disease (PD). Positron emission tomography (PET) with 18F-FDG reveals metabolic perturbations, which are sco
Externí odkaz:
https://doaj.org/article/cf45928cdb0d4da385f7c2688f49c13d
Autor:
Suna Lahut, Suzana Gispert, Özgür Ömür, Candan Depboylu, Kay Seidel, Jorge Antolio Domínguez-Bautista, Nadine Brehm, Hülya Tireli, Karl Hackmann, Caroline Pirkevi, Barbara Leube, Vincent Ries, Kerstin Reim, Nils Brose, Wilfred F. den Dunnen, Madrid Johnson, Zsuzsanna Wolf, Marc Schindewolf, Wiebke Schrempf, Kathrin Reetz, Peter Young, David Vadasz, Achilleas S. Frangakis, Evelin Schröck, Helmuth Steinmetz, Marina Jendrach, Udo Rüb, Ayşe Nazlı Başak, Wolfgang Oertel, Georg Auburger
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 5, Pp 619-631 (2017)
Parkinson's disease (PD) is a frequent neurodegenerative process in old age. Accumulation and aggregation of the lipid-binding SNARE complex component α-synuclein (SNCA) underlies this vulnerability and defines stages of disease progression. Determi
Externí odkaz:
https://doaj.org/article/f247356cd98c40f2b0349f1591cc83ae
Autor:
Stephanie J. Lewis, Nicola Pavese, Maria Rivero-Bosch, Karla Eggert, Wolfgang Oertel, Christopher J. Mathias, David J. Brooks, Alex Gerhard
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 1, Pp 130-136 (2012)
Post-mortem studies of multiple system atrophy (MSA) patients have shown widespread subcortical neurodegeneration. In this study, we have used 18F-dopa PET, a marker of monoaminergic nerve terminal function, to explore in vivo changes in striatal and
Externí odkaz:
https://doaj.org/article/51fbc88c6f4b4115bf5309a9d763e302
Autor:
Jan-Philipp Bach, Maike Gold, David Mengel, Akira Hattesohl, Dirk Lubbe, Severin Schmid, Björn Tackenberg, Jürgen Rieke, Sasidhar Maddula, Jörg Ingo Baumbach, Christoph Nell, Tobias Boeselt, Joan Michelis, Judith Alferink, Michael Heneka, Wolfgang Oertel, Frank Jessen, Sabina Janciauskiene, Claus Vogelmeier, Richard Dodel, Andreas Rembert Koczulla
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132227 (2015)
Alzheimer's disease (AD) is diagnosed based upon medical history, neuropsychiatric examination, cerebrospinal fluid analysis, extensive laboratory analyses and cerebral imaging. Diagnosis is time consuming and labour intensive. Parkinson's disease (P
Externí odkaz:
https://doaj.org/article/85a4814201c24dc98edf82d10ced52b9
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
Autor:
Alexander Gerhard, Nicola Pavese, Gary Hotton, Federico Turkheimer, Meltem Es, Alexander Hammers, Karla Eggert, Wolfgang Oertel, Richard B. Banati, David J. Brooks
Publikováno v:
Neurobiology of Disease, Vol 21, Iss 2, Pp 404-412 (2006)
Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder associated with akinesia, tremor and rigidity. While the characteristic Lewy body pathology targets pigmented and other brainstem nuclei at post-mortem, activated microglia are found
Externí odkaz:
https://doaj.org/article/0ad80639c35845089e4ac632b1dafbe2