Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Wolfgang Nörenberg"'
Autor:
Gabriele Stephan, Lumei Huang, Yong Tang, Sandra Vilotti, Elsa Fabbretti, Ye Yu, Wolfgang Nörenberg, Heike Franke, Flóra Gölöncsér, Beáta Sperlágh, Anke Dopychai, Ralf Hausmann, Günther Schmalzing, Patrizia Rubini, Peter Illes
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-18 (2018)
Two subclasses of ligand-gated ion channels (ASIC3 and P2X3) are both present at sensory neurons and might be therefore subject to receptor crosstalk. Here authors use electrophysiology, biochemistry and co-immunoprecipitation to show that the two io
Externí odkaz:
https://doaj.org/article/a74b5c103f5b4b358a8a947c36ebe64a
Autor:
Gabriele Stephan, Lumei Huang, Yong Tang, Sandra Vilotti, Elsa Fabbretti, Ye Yu, Wolfgang Nörenberg, Heike Franke, Flóra Gölöncsér, Beáta Sperlágh, Anke Dopychai, Ralf Hausmann, Günther Schmalzing, Patrizia Rubini, Peter Illes
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
The originally published version of this article contained an error in the name of the author Flóra Gölöncsér, which was incorrectly given as Flóra Göröncsér. This has now been corrected in both the PDF and HTML versions of the article.
Externí odkaz:
https://doaj.org/article/39b99e51ac91433cb16759ee329bed0c
Autor:
Anna Rössig, Kerstin Hill, Wolfgang Nörenberg, Sebastian Weidenbach, Susanna Zierler, Michael Schaefer, Thomas Gudermann, Vladimir Chubanov
Publikováno v:
Cell calcium. 106
The transient receptor potential cation channel, subfamily M, members 6 and 7 (TRPM6 and TRPM7) are homologous membrane proteins encompassing cation channel units fused to cytosolic serine/threonine-protein kinase domains. Clinical studies and experi
Autor:
Wolfgang Nörenberg, Ye Yu, Sandra Vilotti, Anke Dopychai, Beáta Sperlágh, Heike Franke, Gabriele Stephan, Yong Tang, Elsa Fabbretti, Patrizia Rubini, Ralf Hausmann, Günther Schmalzing, Flóra Gölöncsér, Peter Illes, Lumei Huang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-1 (2018)
Nature Communications 9, 3351 (2018). doi:10.1038/s41467-018-05621-7
Nature Communications
Nature Communications 9, 3351 (2018). doi:10.1038/s41467-018-05621-7
Nature Communications
Two subclasses of acid-sensing ion channels (ASIC3) and of ATP-sensitive P2X receptors (P2X3Rs) show a partially overlapping expression in sensory neurons. Here we report that both recombinant and native receptors interact with each other in multiple
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 350:531-542
Tanshinone II A sulfonate (TIIAS) was identified as a potent, selective blocker of purinergic receptor P2X7 in a compound library screen. In this study, a detailed characterization of the pharmacologic effects of TIIAS on P2X7 is provided. Because TI
Autor:
Wolfgang Fischer, Michael Schaefer, Christoph Hempel, Wolfgang Nörenberg, Günther Schmalzing, Helga Sobottka, T Plötz
Publikováno v:
British Journal of Pharmacology. 167:48-66
BACKGROUND AND PURPOSE In mammalian cells, the anti-parasitic drug ivermectin is known as a positive allosteric modulator of the ATP-activated ion channel P2X4 and is used to discriminate between P2X4- and P2X7-mediated cellular responses. In this pa
Publikováno v:
Journal of Neurochemistry. 121:597-606
J. Neurochem. (2012) 121, 597–606. Abstract In cultured rat neocortical interneurons, we have studied the effect of long-term application of NMDA or AMPA on the surface density of the NMDA (GluN) receptor subunits GluN1 and GluN2B. Stimulation of C
Autor:
Kerstin Wirkner, Patrizia Rubini, Wolfgang Nörenberg, Lars Hartmann, Peter Illes, Doreen Milius, Zoltan S. Zadori, Erzsébet Kató, Peter P. Mager, Doychin Stanchev
Publikováno v:
Journal of Neurochemistry. 107:1216-1224
The human (h) P2X(3) receptor and its mutants deficient in one out of four N-glycosylation sites were expressed in HEK293 cells. Concentration-response curves were generated by whole-cell recordings of alpha,beta-methylene ATP (alpha,beta-meATP)-indu
Autor:
Melanie Kaiser, Anja Penk, Heike Franke, Ute Krügel, Wolfgang Nörenberg, Daniel Huster, Michael Schaefer
Publikováno v:
Purinergic signalling. 12(3)
Effective therapeutic measures against the development of brain edema, a life-threatening complication of cerebral ischemia, are necessary to improve the functional outcome for the patient. Here, we identified a beneficial role of purinergic receptor
Autor:
Thomas Krause, Albrecht Günther, Kerstin Wirkner, László Köles, Marco Weber, Jochen Fuchs, Segundo J. Guzman, Peter Illes, Wolfgang Nörenberg
Publikováno v:
Cerebral Cortex. 17:621-631
Current responses to N-methyl-D-aspartate (NMDA) in layer V pyramidal neurons of the rat prefrontal cortex were potentiated by the P2 receptor agonists adenosine 5'-triphosphate (ATP) and uridine 5'-triphosphate (UTP). The failure of these nucleotide