Výsledky vyhledávání - "Wolfgang Moersig"

Akademický článek

Cancer immunology – development of novel anti-cancer therapies

Autor: Sacha I Rothschild, Daniela S Thommen, Wolfgang Moersig, Philipp Müller, Alfred Zippelius

Publikováno v: Swiss Medical Weekly, Vol 145, Iss 0506 (2015)

The vast majority of tumours are characterised by high frequencies of genetic and epigenetic alterations resulting in tumour-specific antigens, which may, in principle, be recognised by cytotoxic T cells. Though early clinical immunotherapy trials ha

Externí odkaz: https://doaj.org/article/e945a65a05444863951c9039df251083

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Data from Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

Autor: Alfred Zippelius, Didier Lardinois, Vaios Karanikas, Victor Levitsky, Spasenija Savic Prince, Wolfgang Moersig, Ozana S. Fischer, Marina Bacac, Christian Klein, Pavel Pisa, Pablo Umana, Anton Belousov, Andreas Roller, Petra Herzig, Philipp Müller, Jens Schreiner, Daniela S. Thommen

Dysfunctional T cells present in malignant lesions are characterized by a sustained and highly diverse expression of inhibitory receptors, also referred to as immune checkpoints. Yet, their relative functional significance in different cancer types r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dec2145384c4a5a58e14f99be122a0c0
https://doi.org/10.1158/2326-6066.c.6548741.v1

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Supplementary Table 1, Figures 1 - 2 from Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

Supplementary Table 1. Clinical data of NSCLC patients. Supplementary Figure 1. Calculation of the iR score. Supp. Figure 2. Activation of PBMC from healthy donors by polyclonal stimulation.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9ab763a2a78808457fdfb1b1f77975
https://doi.org/10.1158/2326-6066.22538306.v1

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Lungenmetastasen

Autor: Sacha I Rothschild, Alexandros Papachristofilou, Kathleen Jahn, Jens Bremerich, Spasenija Savic Prince, Wolfgang Moersig

Publikováno v: Swiss Medical Forum ‒ Schweizerisches Medizin-Forum. 17

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2297019b7bd32152184fd7f295c49515
https://doi.org/10.4414/smf.2017.03066

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Quality of life in octogenarians after thoracic surgery

Autor: Wolfgang Moersig, Simona Lazdinyte, Didier Lardinois, Andreas Hiebinger, Desiree Schumann

Publikováno v: 8.1 Thoracic Surgery.

OBJECTIVES: Surgery in octogenarians is performed with acceptable morbidity and mortality. However, little is known about the quality of life (QoL) after surgery especially in octogenarians. The goal of this study was to retrospectively examine quali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e824140ddd7cee9d369998e231533500
https://doi.org/10.1183/13993003.congress-2016.pa2496

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Expression of inhibitory receptors on intratumoral T cells modulates the activity of a T cell-bispecific antibody targeting folate receptor

Autor: M von Bergwelt-Baildon, Victor Levitsky, Philipp Müller, Pablo Umana, Alfred Zippelius, Viola Heinzelmann-Schwarz, Anton Belousov, Vaios Karanikas, Franziska Uhlenbrock, Andreas Roller, Spasenija Savic, Marina Bacac, Didier Lardinois, Jens Schreiner, Wolfgang Moersig, Petra Herzig, Daniela S. Thommen, Pavel Pisa, Christian Klein

Publikováno v: Oncoimmunology. 5(2)

T-cell bispecific antibodies (TCBs) are a novel therapeutic tool designed to selectively recruit T-cells to tumor cells and simultaneously activate them. However, it is currently unknown whether the dysfunctional state of T-cells, embedded into the t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e6c0cbb53317ad51a1ffcfefb4a564
https://pubmed.ncbi.nlm.nih.gov/27057429

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Progression of Lung Cancer Is Associated with Increased Dysfunction of T Cells Defined by Coexpression of Multiple Inhibitory Receptors

Autor: Pablo Umana, Jens Schreiner, Didier Lardinois, Marina Bacac, Philipp Müller, Alfred Zippelius, Spasenija Savic Prince, Christian Klein, Pavel Pisa, Ozana S. Fischer, Victor Levitsky, Anton Belousov, Vaios Karanikas, Wolfgang Moersig, Andreas Roller, Petra Herzig, Daniela S. Thommen

Publikováno v: Cancer immunology research. 3(12)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46fd763cf6e5263798de90b59f4bb621
https://pubmed.ncbi.nlm.nih.gov/26253731

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Proliferative activity in stenotic human aortocoronary bypass grafts

Autor: Gudrun Tellmann, Michael Hilker, Michael Buerke, Karin Gloger, Wolfgang Moersig, Ulrich Hake, H. Oelert, Hans-Anton Lehr

Publikováno v: Cardiovascular Pathology. 11:284-290

Background: Aortocoronary bypass graft disease is responsible for long-term failure of autologous vein grafts. The analyses of proliferation and cell type characterisation in human bypass grafts harvested during re-do surgery make it possible to inve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d2db20184ab9c1fe6e1f830e8055e0
https://doi.org/10.1016/s1054-8807(02)00113-8

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