Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Wolfgang Merkt"'
Autor:
Oiwi Parker Jones, Alexander L. Mitchell, Jun Yamada, Wolfgang Merkt, Mathieu Geisert, Ioannis Havoutis, Ingmar Posner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Sensorimotor control of complex, dynamic systems such as humanoids or quadrupedal robots is notoriously difficult. While artificial systems traditionally employ hierarchical optimisation approaches or black-box policies, recent results in sy
Externí odkaz:
https://doaj.org/article/6309d8ed7b4546a0968a342e20f4e231
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Objective Previous technical limitations prevented the proof of Fcγ-receptor (FcγR)-activation by soluble immune complexes (sICs) in patients. FcγRIIIa (CD16) is a risk factor in rheumatoid arthritis (RA). We aimed at determining the presence of C
Externí odkaz:
https://doaj.org/article/f3ae4914a3f044ad8338a9dd3d730f5e
Autor:
Inga Viktoria Hensel, Szabolcs Éliás, Michelle Steinhauer, Bilgenaz Stoll, Salvatore Benfatto, Wolfgang Merkt, Stefan Krienke, Hanns-Martin Lorenz, Jürgen Haas, Brigitte Wildemann, Martin Resnik-Docampo
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 547-574 (2024)
Abstract Human intestinal epithelial cells are the interface between luminal content and basally residing immune cells. They form a tight monolayer that constantly secretes mucus creating a multilayered protective barrier. Alterations in this barrier
Externí odkaz:
https://doaj.org/article/b7aabe92d90649c6adf10c4fefcf4995
Autor:
Wolfgang Merkt, Ulrich Salzer, Jens Thiel, Ilona Jandova, Raoul Bergner, Ana C. Venhoff, Nils Venhoff
Publikováno v:
BMC Immunology, Vol 22, Iss 1, Pp 1-13 (2021)
Abstract Background Cytotoxic Natural Killer (NK) cells are increasingly recognized as a powerful tool to induce targeted cell death in cancer and autoimmune diseases. Still, basic blood NK cell parameters are poorly defined. The aims of this study w
Externí odkaz:
https://doaj.org/article/a810254672604bf9871f35c030c92bf7
Autor:
Peter Kvacskay, Nina Yao, Jürgen-Heinz Schnotz, Roberta Scarpone, Rui de Albuquerque Carvalho, Karel D. Klika, Wolfgang Merkt, Theresa Tretter, Hanns-Martin Lorenz, Lars-Oliver Tykocinski
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-15 (2021)
Abstract Background A dysregulated glucose metabolism in synovial fibroblasts (SF) has been associated with their aggressive phenotype in rheumatoid arthritis (RA). Even though T helper (Th) cells are key effector cells in the propagation and exacerb
Externí odkaz:
https://doaj.org/article/1a335b7d74db4ce9bd0f8b950241b6de
Autor:
Doris Urlaub, Shuyang Zhao, Norbert Blank, Raoul Bergner, Maren Claus, Theresa Tretter, Hanns-Martin Lorenz, Carsten Watzl, Wolfgang Merkt
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Objective In the last few years, anti-CD20 antibody rituximab profoundly changed the therapeutic landscape of granulomatosis with polyangiitis (GPA). Here, we investigated whether natural killer (NK) cells may play a role in rituximab’s me
Externí odkaz:
https://doaj.org/article/cecf829c83b049bcb9ae221678273532
Autor:
Nina Yao, Theresa Tretter, Peter Kvacskay, Wolfgang Merkt, Norbert Blank, Hanns-Martin Lorenz, Lars-Oliver Tykocinski
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1413 (2021)
Crosstalk between synovial fibroblasts (SF) and immune cells plays a central role in the development of rheumatoid arthritis (RA). Janus kinase inhibitors (JAKi) have proven efficacy in the treatment of RA, although clinical responses are heterogeneo
Externí odkaz:
https://doaj.org/article/cdffbb70c7c54ac699baada31e8054ed
Autor:
Carsten Watzl, Lars-Oliver Tykocinski, Philipp Kolb, Shuyang Zhao, Guido H. Wabnitz, Deepak A. Rao, Ivana Andreeva, T. Tretter, Wolfgang Merkt, Haizhang Chen, Ricardo Grieshaber-Bouyer, Hanns-Martin Lorenz
Publikováno v:
Arthritis & Rheumatology. 74:441-452
Objectives Recent transcriptome analyses revealed that 15-fold expanded HLA-DR+ CD90+ synovial fibroblasts (SFs) are potential key mediators of inflammation in rheumatoid arthritis (RA). The reasons for the expansion of HLA-DR+ CD90+ SFs are unclear,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::210c3baf96b3148e8a1c4b7bdf4b7a3c
https://doi.org/10.1002/art.41958
https://doi.org/10.1002/art.41958
Publikováno v:
Towards Autonomous Robotic Systems ISBN: 9783030891763
TAROS
TAROS
Central Pattern Generators (CPGs) have several properties desirable for locomotion: they generate smooth trajectories, are robust to perturbations and are simple to implement. Although conceptually promising, we argue that the full potential of CPGs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1990ef15c7624026934df6e0f900083d
https://ora.ox.ac.uk/objects/uuid:6bd9ba19-4648-414f-b77c-624b89a58655
https://ora.ox.ac.uk/objects/uuid:6bd9ba19-4648-414f-b77c-624b89a58655
Autor:
Carlos Mastalli, Wolfgang Merkt, Josep Marti-Saumell, Henrique Ferrolho, Joan Solà, Nicolas Mansard, Sethu Vijayakumar
Publikováno v:
Mastalli, C, Merkt, W, Marti-Saumell, J, Ferrolho, H, Solà, J, Mansard, N & Vijayakumar, S 2022, ' A feasibility-driven approach to control-limited DDP ', Autonomous Robots, vol. 46, no. 8, pp. 985-1005 . https://doi.org/10.1007/s10514-022-10061-w
Differential dynamic programming (DDP) is a direct single shooting method for trajectory optimization. Its efficiency derives from the exploitation of temporal structure (inherent to optimal control problems) and explicit roll-out/integration of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c49b7cbf78eae93307b8294ff55a808
http://hdl.handle.net/10261/295729
http://hdl.handle.net/10261/295729