Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Wolfgang Melchinger"'
Autor:
Isis Wolf, Jonas Storz, Susanne Schultze-Seemann, Philipp R. Esser, Stefan F. Martin, Susan Lauw, Peer Fischer, Marie Peschers, Wolfgang Melchinger, Robert Zeiser, Oliver Gorka, Olaf Groß, Christian Gratzke, Reinhard Brückner, Philipp Wolf
Publikováno v:
Bioactive Materials, Vol 41, Iss , Pp 537-552 (2024)
Photoimmunotherapy (PIT) combines the specificity of antibodies with the cytotoxicity of light activatable photosensitizers (PS) and is a promising new cancer therapy. We designed and synthesized, in a highly convergent manner, the silicon phthalocya
Externí odkaz:
https://doaj.org/article/ee35b5cb8cf245868148c021c5ec968b
Autor:
Kristina Maas-Bauer, Anna-Verena Stell, Kai-Li Yan, Enrique de Vega, Janaki Manoja Vinnakota, Susanne Unger, Nicolas Núñez, Johana Norona, Nana Talvard-Balland, Stefanie Koßmann, Carsten Schwan, Cornelius Miething, Uta S. Martens, Khalid Shoumariyeh, Rosa P. Nestor, Sandra Duquesne, Kathrin Hanke, Michal Rackiewicz, Zehan Hu, Nadia El Khawanky, Sanaz Taromi, Hana Andrlova, Hemin Faraidun, Stefanie Walter, Dietmar Pfeifer, Marie Follo, Johannes Waldschmidt, Wolfgang Melchinger, Michael Rassner, Claudia Wehr, Annette Schmitt-Graeff, Sebastian Halbach, James Liao, Georg Häcker, Tilman Brummer, Joern Dengjel, Geoffroy Andrieux, Robert Grosse, Sonia Tugues, Bruce R. Blazar, Burkhard Becher, Melanie Boerries, Robert Zeiser
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Patients with corticosteroid-refractory acute graft-versus-host disease (aGVHD) have a low one-year survival rate. Identification and validation of novel targetable kinases in patients who experience corticosteroid-refractory-aGVHD may help
Externí odkaz:
https://doaj.org/article/cb63dbf7545c4a79898fb5a39c9842f1
Autor:
Robert Zeiser, Melanie Boerries, Frank Meiss, Annette Schmitt-Graeff, Heide Dierbach, Dietmar Pfeifer, Geoffroy Andrieux, Martina Falk, Dominik Schmidt, Sandra Duquesne, Wolfgang Melchinger, Kathrin Hanke, Hana Andrlova, Natalie Stickel, Justin Mastroianni
(S1) Supplemental Figure S1 shows the flow cytometry based analysis of B16 cells transformed with a lentiviral vector with Luc-GFP-neo (S2-S7) Supplemental Figures S2-S7 show complete western blot images (S8) Supplemental Figure S8 shows the impact o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af626e15fb0ad00f4a702f1e8dc82825
https://doi.org/10.1158/0008-5472.22420649
https://doi.org/10.1158/0008-5472.22420649
Autor:
Robert Zeiser, Melanie Boerries, Frank Meiss, Annette Schmitt-Graeff, Heide Dierbach, Dietmar Pfeifer, Geoffroy Andrieux, Martina Falk, Dominik Schmidt, Sandra Duquesne, Wolfgang Melchinger, Kathrin Hanke, Hana Andrlova, Natalie Stickel, Justin Mastroianni
MicroRNAs (miR) are small noncoding RNAs that regulate gene expression, posttranscription, and manipulate immune responses in different types of cancers. In this study, we identify miR-146a as a negative regulator of immune activation, comparable to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b5c10285d6ace20f4da7fb158ea61f
https://doi.org/10.1158/0008-5472.c.6510707
https://doi.org/10.1158/0008-5472.c.6510707
Autor:
Heide Dierbach, Justin Mastroianni, Annette Schmitt-Graeff, Martina Falk, Natalie Stickel, Dietmar Pfeifer, Melanie Boerries, Kathrin Hanke, Wolfgang Melchinger, Sandra Duquesne, Dominik Schmidt, Frank Meiss, Hana Andrlová, Geoffroy Andrieux, Robert Zeiser
Publikováno v:
Cancer Research. 79:183-195
MicroRNAs (miR) are small noncoding RNAs that regulate gene expression, posttranscription, and manipulate immune responses in different types of cancers. In this study, we identify miR-146a as a negative regulator of immune activation, comparable to
Autor:
Sebastian Halbach, Marina Kreutz, Joy Edwards-Hicks, Melanie Boerries, Justus Duyster, Jörg Büscher, Tobias Madl, Olaf Groß, Sandra Duquesne, David O’Sullivan, Eileen Haring, Wolfgang Melchinger, Gesa Richter, Petya Apostolova, Tilman Brummer, Michael Lübbert, Erika L. Pearce, Franziska M. Uhl, Barbara Sauer, Sophia Chen, Bruce R. Blazar, Geoffroy Andrieux, Robert Zeiser, Annette Schmitt-Graeff, Khalid Shoumariyeh
Publikováno v:
Sci Transl Med
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Acute myeloid leukemia (AML) relapse after allogeneic hematopoietic cell transplantation (allo-HCT) has a dismal prognosis. We found that T cells of patients relapsing with AML after allo-HCT exhibited reduced glycolysis and interferon-γ production.
Autor:
Xingxing Zang, Angela Panoskaltsis-Mortari, Patricia A. Taylor, Jonathan S. Serody, Yosef Refaeli, William J. Murphy, David H. Munn, Shuyu Huang, Marcel R.M. van den Brink, Ivan Maillard, Govindarajan Thangavelu, James P. Allison, Mark J. Osborn, Robert Zeiser, Christopher J. Lees, Chen Dong, Bruce R. Blazar, Geoffrey R. Hill, Asim Saha, Colby J. Feser, Wolfgang Melchinger, Katharina Kreymborg
Publikováno v:
JCI insight, vol 4, iss 19
B7-H4 is a negative regulatory B7 family member. We investigated the role of host and donor B7-H4 in regulating acute graft-versus-host disease (GVHD). Allogeneic donor T cells infused into B7-H4(–/–) versus WT recipients markedly accelerated GVH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27edc662f02378de269742dcdcadaf2a
https://escholarship.org/uc/item/93d3n7ct
https://escholarship.org/uc/item/93d3n7ct
Autor:
Andreas Narr, Josef Madl, Susana Minguet, Melanie Boerries, Paul Timpson, Kristin Technau-Hafsi, Cristina Has, Winfried Römer, Justin Mastroianni, Robert Zeiser, Marco Idzko, Hauke Busch, Annette Schmitt-Graeff, Venugopal Rao Mittapalli, Claire Vennin, Heide Dierbach, Florian Wernet, Wolfgang Melchinger, Johannes S. Kern, Gabriele Ihorst, Ricarda Herr, Hendrik Ungefroren, Justus Duyster, Tilman Brummer, Hana Andrlová, Marie Follo, Frank Meiss
Publikováno v:
Oncotarget
// Hana Andrlova 1 , Justin Mastroianni 1 , Josef Madl 2, 3 , Johannes S. Kern 4 , Wolfgang Melchinger 1 , Heide Dierbach 1 , Florian Wernet 1 , Marie Follo 1 , Kristin Technau-Hafsi 4 , Cristina Has 4 , Venugopal Rao Mittapalli 4 , Marco Idzko 5 , R
Autor:
Khalid Shoumariyeh, Robert Zeiser, Sivahari P. Gorantla, Sebastian Halbach, Frederike A. Hartl, Alica J. Emhardt, Julius Wehrle, Jonas S. Jutzi, Sebastian Fuchs, Ioanna Triviai, Sandra Duquesne, Michael Hettich, Annette Schmitt-Graeff, Eliana Ruggiero, Susana Minguet, Wolfgang Melchinger, Jürgen Finke, Chiara Bonini, Nicolaus Kröger, Pia Veratti, Anna Lena Illert, Bruce R. Blazar, Melanie Boerries, Mark Bartholomä, Teresa Poggio, Geoffrey R. Hill, Steven W. Lane, Gabriele Niedermann, Petya Apostolova, Slavica Vuckovic, Nikolas von Bubnoff, Konrad Aumann, Hauke Busch, Stephan Ehl, Florian H. Heidel, Sandra Pennisi, Dietmar Pfeifer, Justus Duyster, Cornelius Miething, David O’Sullivan, Marie Follo, Lukas Braun, Christine Dierks, Heiko Becker, Heike L. Pahl, Jan Rohr, Tilman Brummer, Alessandro Prestipino, Erika L. Pearce
Publikováno v:
Science Translational Medicine
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Recent evidence has revealed that oncogenic mutations may confer immune escape. A better understanding of how an oncogenic mutation affects immunosuppressive programmed death ligand 1 (PD-L1) expression may help in developing new therapeutic strategi
Autor:
Donald Bunjes, Sebastian Halbach, Dietmar Pfeifer, Philipp Hemmati, Robert S. Negrin, Fabio Ciceri, Jean-Yves Cahn, Markus Ditschkowski, Pavan Reddy, Kathrin Hanke, Daniela Dörfel, Susan Klaeger, Jürgen Finke, Zehan Hu, Gabriele Ihorst, Gérard Socié, Sanaz Taromi, Andreas Hochhaus, Glen A Kennedy, Omid Shah, Andreas Neubauer, Robert Thimme, Michael Schultheiss, Sabine Spath, Dietrich W. Beelen, Sandra Duquesne, Arnim Weber, Geoffrey R. Hill, Ronjon Chakraverty, Jürgen Kuball, Guido Kobbe, Nikolas von Bubnoff, Andrea S. Henden, Betul Oran, Burkhard Becher, Bernhard Kuster, Christoph Rummelt, Lena Osswald, Hartmut Bertz, Wolfgang Bethge, Eva-Maria Wagner, Arnon Nagler, Eliana Ruggiero, Saar Gill, Miguel Waterhouse, Andreas Mackensen, Dominik Bettinger, Francis Baumgartner, Florian Kuchenbauer, Anita Sarma, Takanori Teshima, Erika L. Pearce, Antonia M.S. Müller, Kathleen Stabla, John M. Magenau, Evelyn Ullrich, Nicolaus Kröger, Georg Häcker, Simone Thomas, Myriam Labopin, Ghulam J. Mufti, Jan E. Ehlert, Lutz P. Müller, Marie Follo, Dominik Wolf, Tony Andreas Müller, Michael Lübbert, Jacqueline Schnell, Christof Scheid, Takeshi Kondo, Donal P. McLornan, Thomas Pabst, Konrad Wilhelm, Chiara Bonini, Wolf Rösler, Simon Richardson, Cordula A. Jilg, Andrea Schmidts, Luca Vago, Joseph H. Antin, Annette Schmitt-Graeff, Yakup Tanriver, Michael A. Caligiuri, Wolfgang Herr, Kai-Li Yan, Lukas Braun, Daniel J. Weisdorf, Katayoun Rezvani, Giang Lam Vuong, Tilman Brummer, Stephan Meckel, Ralph Wäsch, Geoffroy Andrieux, Soroush Doostkam, Hauke Busch, Dennis Dong Hwan Kim, Sabine Gerull, Bruce R. Blazar, Robert Zeiser, Merav Bar, Flore Sicre-de-Fontbrune, Daniel Feger, Melanie Börries, Wolfgang Melchinger, Petya Apostolova, C. Leiber, Udo Holtick, Walter J.F.M. van der Velden, Renate Arnold, Rainer Claus, Justus Duyster, Nimitha R. Mathew, David O’Sullivan, Alexandros Spyridonidis, S K Metzelder, Thomas Schroeder, Jörg Halter, Johanna Haag, Friedrich Stölzel, Christoph Schmid, Anna Lena Illert, Claudia Lengerke, Björn Hackanson, Joern Dengjel, Francis Ayuk, Rainer Ordemann, Sonia Tugues, Marco Prinz, Inken Hilgendorf, Andreas Burchert
Publikováno v:
Nature Medicine
Nature Medicine, 24, 282-291
Nature Medicine, 24, 3, pp. 282-291
Nature Medicine, 24, 282-291
Nature Medicine, 24, 3, pp. 282-291
Contains fulltext : 190745.pdf (Publisher’s version ) (Closed access) Individuals with acute myeloid leukemia (AML) harboring an internal tandem duplication (ITD) in the gene encoding Fms-related tyrosine kinase 3 (FLT3) who relapse after allogenei