Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Wolfgang Krupp"'
Autor:
Marco Wallenborn, Li-Xin Xu, Holger Kirsten, Leili Rohani, Daniela Rudolf, Peter Ahnert, Christian Schmidt, Ronny M Schulz, Mandy Richter, Wolfgang Krupp, Wolf Mueller, Adiv A Johnson, Jürgen Meixensberger, Heidrun Holland
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0234986 (2020)
Glioblastoma is a common, malignant brain tumor whose disease incidence increases with age. Glioblastoma stem-like cells (GSCs) are thought to contribute to cancer therapy resistance and to be responsible for tumor initiation, maintenance, and recurr
Externí odkaz:
https://doaj.org/article/49a74c104af148c38165885718938826
Autor:
Vera Reuschel, Vivian Pascal Brandt, Christan Eisenlöffel, Peter Ahnert, Caroline Sander, Heidrun Holland, Marco Wallenborn, Wolfgang Krupp, Jürgen Meixensberger
Publikováno v:
Pathology, research and practice. 215(7)
The central neurocytoma (CN) is a rare brain tumor with a frequency of 0.1-0.5% of all brain tumors. According to the World Health Organization classification, it is a benign grade II tumor with good prognosis. However, some CN occur as histologicall
Publikováno v:
Journal of neuro-oncology. 140(2)
Patients who are diagnosed with high-grade gliomas (HGG) have poor prognoses and often experience rapid declines in functional and cognitive status, which makes caring for them particularly stressful. We conducted a prospective study to investigate t
Autor:
Wolf Mueller, Helene Hantmann, Tanja Gradistanac, Heidrun Holland, J. Meixensberger, Clara Frydrychowicz, Karl Titus Hoffmann, Wolfgang Krupp
Publikováno v:
Neuropathology. 35:175-183
We present two cases of atypical meningioma WHO grade II with a history of multiple local recurrences and late pulmonary metastases. Comparative cytogenetic analyses on 1p and 22q confirmed clonal origin of the primary intracranial meningiomas and th
Autor:
Ronald Koschny, Holger Kirsten, Li-Xin Xu, Ralf Schober, Peter Ahnert, Dominik Fritzsch, Manfred Bauer, Heidrun Holland, Wolfgang Krupp, Wolf Mueller, Jürgen Meixensberger
Publikováno v:
Neuropathology. 35:148-157
According to the World Health Organization gangliogliomas are classified as well-differentiated and slowly growing neuroepithelial tumors, composed of neoplastic mature ganglion and glial cells. It is the most frequent tumor entity observed in patien
Autor:
Wolf Mueller, Wolfgang Krupp, Christina Boehm, Thomas Koschny, Peter Sinn, Heidrun Holland, Martin R. Sprick, Ronald Koschny, Tobias L. Haas, Marius Keller, Manfred Bauer, J. Meixensberger, Li-Xin Xu, Tom M. Ganten, Henning Walczak
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 73:1034-1046
A meningioma is the most common primary intracranial tumor in adults. Here, we investigated the therapeutic potential of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in 37 meningiomas. Freshly isolated primary meningioma cells
Autor:
Heidrun Holland, Wolfgang Krupp, Holger Kirsten, Peter Ahnert, Ronald Koschny, Jürgen Meixensberger, Manfred Bauer, Ralf Schober, Kristin Mocker
Publikováno v:
Pathology - Research and Practice. 207:67-72
Multiple meningiomas with synchronous tumor lesions represent only 1–9% of all meningiomas and usually show a uniform histology. The simultaneous occurrence of different grades of malignancy in these nodules is observed in only one third of multipl
Autor:
Hande Erdal, Ronald Koschny, Wolfgang Krupp, Manfred Bauer, Ulrike Bockmuehl, Jaromir Sykora, Tom M. Ganten, Jürgen Meixensberger, Wolfgang Stremmel, Henning Walczak, Heidrun Holland, Peter Ahnert
Publikováno v:
Journal of Neuro-Oncology. 97:171-185
TNF-related apoptosis-inducing ligand (TRAIL), a promising novel anti-cancer cytokine of the TNF superfamily, and Bortezomib, the first-in-class clinically used proteasome inhibitor, alone or in combination have been shown to efficiently kill numerou
Publikováno v:
Cancer Genetics and Cytogenetics. 153:32-38
Diffuse astrocytomas are highly variable tumors and show complex biologic behavior that is based on multi-step oncogenesis. We report cytogenetic and molecular cytogenetic investigations in 23 cases of diffuse astrocytomas. The results of conventiona
Publikováno v:
Cancer Genetics and Cytogenetics. 138:111-115
A case of glioblastoma multiforme (GBM) that was investigated with a broad spectrum of cytogenetic and molecular cytogenetic techniques is reported. The results of cytogenetic studies, interphase fluorescence in situ hybridization, comparative genomi