Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Wolfgang Kreis"'
Autor:
Christoph Rieck, Daniel Geiger, Jennifer Munkert, Katrin Messerschmidt, Jan Petersen, Juliane Strasser, Nadine Meitinger, Wolfgang Kreis
Publikováno v:
MicrobiologyOpen, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract A yeast expression plasmid was constructed containing a cardenolide biosynthetic module, referred to as CARD II, using the AssemblX toolkit, which enables the assembly of large DNA constructs. The genes cloned into the vector were (a) a Δ5
Externí odkaz:
https://doaj.org/article/66f285ad80934f78860eb73c4d014a34
Autor:
Jan Klein, Mona Ernst, Alexander Christmann, Marina Tropper, Tim Leykauf, Wolfgang Kreis, Jennifer Munkert
Publikováno v:
Metabolites, Vol 12, Iss 1, p 11 (2021)
Small or specialized natural products (SNAPs) produced by plants vary greatly in structure and function, leading to selective advantages during evolution. With a limited number of genes available, a high promiscuity of the enzymes involved allows the
Externí odkaz:
https://doaj.org/article/9290f634e1f04b8dae0ff62e05da2fb4
Autor:
Wolfgang Kreis
Publikováno v:
Journal of Applied Botany and Food Quality, Vol 92 (2019)
The initiation of callus cultures and in vitro cultivation of plant cells, even in large bioreactors, has become a routine task. Despite the fact, that permanent cell and organ cultures can produce a whole range of small natural compounds (SNAPs) use
Externí odkaz:
https://doaj.org/article/b5c6d412956e4d9fa7f251ac5d9a1f5b
Autor:
Laurita Boff, André Schreiber, Aline da Rocha Matos, Juliana Del Sarto, Linda Brunotte, Jennifer Munkert, Flaviano Melo Ottoni, Gabriela Silva Ramos, Wolfgang Kreis, Fernão Castro Braga, Ricardo José Alves, Rodrigo Maia de Pádua, Cláudia Maria Oliveira Simões, Stephan Ludwig
Publikováno v:
Molecules, Vol 25, Iss 20, p 4853 (2020)
Influenza virus infections represent a major public health issue by causing annual epidemics and occasional pandemics that affect thousands of people worldwide. Vaccination is the main prophylaxis to prevent these epidemics/pandemics, although the ef
Externí odkaz:
https://doaj.org/article/41e396721b984707852822a3b8d6e6b2
Autor:
Nadine Meitinger, Wolfgang Kreis
Publikováno v:
Journal of Applied Botany and Food Quality, Vol 91 (2018)
A quick assay to determine the total glucosinolate content of fresh horseradish roots in less than 10 minutes is described. The method involves the following steps: 1. Maceration of horseradish root with 4% phosphoric acid to avoid enzymatic degradat
Externí odkaz:
https://doaj.org/article/8bb37188b14946069f3b2be12bfdafd3
Autor:
Naira F. Z. Schneider, Claudia Cerella, Jin-Young Lee, Aloran Mazumder, Kyung Rok Kim, Annelise de Carvalho, Jennifer Munkert, Rodrigo M. Pádua, Wolfgang Kreis, Kyu-Won Kim, Christo Christov, Mario Dicato, Hyun-Jung Kim, Byung Woo Han, Fernão C. Braga, Cláudia M. O. Simões, Marc Diederich
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cardiac glycosides (CGs) are natural compounds used traditionally to treat congestive heart diseases. Recent investigations repositioned CGs as potential anticancer agents. To discover novel cytotoxic CG scaffolds, we selected the cardenolide glucoev
Externí odkaz:
https://doaj.org/article/1962657514af42deb6f0eab6afdc2661
Publikováno v:
Química Nova, Vol 20, Iss 5, Pp 481-485 (1997)
The content of digoxin and lanatoside C (jointly quantified), lanatoside A, lanatoside B, glucoevatromonoside, odorobioside G, glucogitoroside, glucoverodoxine, glucodigifucoside and digitalinum verum was determined by HPLC in Digitalis lanata harves
Externí odkaz:
https://doaj.org/article/809af5faa361406d92ca821716807499
Autor:
Giselly Mota da Silva, Alliyu Mohamed, Alexandre Alves de Carvalho, José Eduardo Brasil Pereira Pinto, Fernão Castro Braga, Rodrigo Maia de Pádua, Wolfgang Kreis, Suzan Kelly Vilela Bertolucci
Publikováno v:
Plant Cell, Tissue and Organ Culture (PCTOC). 151:93-105
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::580c7f4d4974ae71a15d1f55b7787c13
https://doi.org/10.1007/s11240-022-02333-1
https://doi.org/10.1007/s11240-022-02333-1
Autor:
Tim Leykauf, Jan Klein, Mona Ernst, Maja Dorfner, Anastasiia Ignatova, Wolfgang Kreis, Harald Lanig, Jennifer Munkert
Publikováno v:
Planta Medica.
3β-hydroxy-Δ5-steroid dehydrogenases (3βHSDs) are supposed to be involved in 5β-cardenolide biosynthesis. Here, a novel 3βHSD (Dl3βHSD2) was isolated from Digitalis lanata shoot cultures and expressed in E. coli. Recombinant Dl3βHSD1 and Dl3β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc7f2d3213a6cef04f8d43daaa138941
https://doi.org/10.1055/a-2074-9186
https://doi.org/10.1055/a-2074-9186
Autor:
Lara Persich, Fátima Regina Mena Barreto Silva, Cláudia Maria Oliveira Simões, Vanessa Faria Cortes, Sayonarah C. Rocha, Carlos Frederico Leite Fontes, Fernão Castro Braga, Ana Carolina Pacheco Ramos, Wolfgang Kreis, Andre Dagostin, Danusa Menegaz, Jennifer Munkert, Rodrigo Maia de Pádua, Leandro A. Barbosa, Naira Fernanda Zanchett Schneider
Publikováno v:
Molecular and Cellular Biochemistry. 476:1825-1848
Cardiac glycosides (CGs) are useful drugs to treat cardiac illnesses and have potent cytotoxic and anticancer effects in cultured cells and animal models. Their receptor is the Na+,K+ ATPase, but other plasma membrane proteins might bind CGs as well.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af089034ebe22e7f57cee073bb79d736
https://doi.org/10.1007/s11010-020-04040-x
https://doi.org/10.1007/s11010-020-04040-x