Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Wolfgang Kraas"'
Publikováno v:
The Journal of Peptide Research. 51:127-133
An investigation of the stability of the Dde protecting group for amines, used in solid-phase peptide synthesis, shows that an unprotected epsilon-NH2 group of lysine can acquire the Dde protection from another epsilon-NH2 group or from an alpha-NH2
Publikováno v:
Letters in Peptide Science. 6:135-142
New hydrophilic linkers of the formula Fmoc-NHCH2CH2COO(CH2CH2O)4X (X=COCH2CH2COOH Fmoc-Ats (2), X=CONHCH2COOH Fmoc-Atg (4) and X=CONHCH2CH2COOH Fmoc-Ata (5) have been prepared by heterobifunctional modification of tetraethylene glycol as starting ma
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:1669-1672
Five sets of N-acylated tetrapeptide libraries and sublibraries related to Nazumamide A have been prepared using 25 natural and unnatural amino acids. They were evaluated in antithrombin assay, in order to quantify inhibition at each step of the tetr
Autor:
Günther Jung, Hans-Georg Ihlenfeldt, Christoph Seidel, Wolfgang Kraas, Ulla Wienhues, Urban Schmitt
Publikováno v:
Virology. 245:281-288
Mapping and possible diagnostic meaning of a highly conserved, linear NS4 epitope (NS4/3), located outside the C100-3 antigen within the carboxyl terminal proportion of the NS4 region, with major immunoreactivity with specimens of patients with HCV i
Autor:
Günther Jung, Wolfgang Kraas, Volkmar Braun, Helmut Killmann, Athanasios Mademidis, Insa Flechsler
Publikováno v:
Molecular Microbiology. 26:1109-1123
The Escherichia coli iron transport system via ferrichrome belongs to the group of ATP-dependent transporters that are widely distributed in prokaryotes and eukaryotes. Transport across the cytoplasmic membrane is mediated by three proteins: FhuD in
Publikováno v:
Journal of Molecular Biology. 272:484-492
The herpes simplex virus type 1 (HSV-1) protein ICP47 binds specifically to the transporter associated with antigen processing (TAP), thereby blocking peptide-binding and translocation by TAP and subsequent loading of peptides onto MHC class I molecu
Autor:
Stefan Kienle, Wolfgang Kraas, Günther Jung, Karl-Heinz Wiesmüller, Robert Tampé, Stephan Uebel
Publikováno v:
Proceedings of the National Academy of Sciences. 94:8976-8981
Transport of peptides across the membrane of the endoplasmic reticulum for assembly with MHC class I molecules is an essential step in antigen presentation to cytotoxic T cells. This task is performed by the major histocompatibility complex-encoded t
Publikováno v:
Biosensors and Bioelectronics. 12:779-786
In this paper, the combination of surface plasmon resonance (SPR) with an electrochemical method for surface modification is presented. The SLP1 sequence of the sodium channel protein of rat cardiac muscle cells was N-terminally modified with an elec
Publikováno v:
Chemistry - A European Journal. 2:667-672
For the first time, antigenic peptides have been immobilised by electrochemical polymerisation after having been modified with a polymerisable functional group. 3-Hydroxyphenylacetic acid was chosen as the novel polymerisable group. The synthetic pep
Publikováno v:
Biosensors and Bioelectronics. 11:591-598
We report on the use of quartz crystal microbalances (QCMs) for on-line detection of bioaffinity interactions. The QCM transducer is of reasonable simplicity as compared to other transducers used in direct affinity sensing. However, the performance a