Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Wolfgang Klinger"'
Autor:
Florentine Jahn, Wolfgang Klinger
Publikováno v:
Acta Pharmacologica et Toxicologica. 50:85-88
Cadmium++ added in vitro destroys rat liver cytochrome P-450 (cyt. P-450) with increasing age by 25–50%. Ethylmorphine N-demethylation is inhibited only in rats 30-days old and thereafter. Ethoxycoumarin 0-deethylation is inhibited even in newborn
Autor:
Stefan O. Schoenberg, Herwig Imhof, Christian Glaser, Iris-M. Noebauer-Huhmann, Claus-Peter Wallner, Wolfgang Klinger, Olaf Dietrich
Publikováno v:
European Radiology. 17:1147-1155
To compare the quality of cervical spine MR images obtained by parallel imaging [generalized autocalibrating partially parallel acquisition (GRAPPA)] with those of non-accelerated imaging, we conducted both phantom studies and examinations of ten vol
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 30:203-218
Fibrates lead to a reduction of serum triglycerides and cholesterol in hyperlipidemic patients. Their therapeutic use, however, can be associated with adverse effects like gastrointestinal disorders, myalgia, myositis and hepatotoxicity. Large doses
Publikováno v:
Transplant International. 15:96-107
Syngenic fetal liver tissue suspensions were transplanted into the spleens of 60- to 90-day-old male Fischer 344 inbred rats. Transplant recipients were compared with age-matched control rats. One year after surgery, the animals were treated orally w
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 26:31-35
In vitro melatonin binds to human and rat liver microsomal cytochrome P-450 (P450) according to a type II substrate. The affinity is similar to that of aniline with a general left-shift. Melatonin interferes with model monooxygenase reactions indicat
Publikováno v:
Experimental and Toxicologic Pathology. 52:529-538
Syngenic fetal liver tissue suspensions were transplanted into the spleens of adult male Fisher 344 inbred rats. Four months after surgery, transplant recipients and age matched control rats were treated with different cytotoxins (allyl alcohol [AAL]
Publikováno v:
Experimental and Toxicologic Pathology. 52:381-393
Syngenic fetal liver tissue suspensions were transplanted into the spleens of adult male Fisher 344 inbred rats. Four months after surgery, transplant recipients and age matched control rats were treated with different cytotoxins (allyl alcohol [AAL]
Publikováno v:
Europe PubMed Central
Metabolic pathways of oestrogens are the formation of catechol oestrogens (CE; 2- and 4-hydroxy-oestrogens), redox cycling of CE and free radical generation, mediated through cytochrome P450 (P450) oxidase/reductase activity. We checked the oestrogen
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 24:63-68
Both chlormezanone enantiomers, for the first time obtained by enantiospecific HPLC with a 100% yield, bind to oxidized cytochrome P-450 in rat liver microsomes with a binding curve according to type I, similar to hexobarbital but less pronounced. Th
Publikováno v:
Journal of Bioluminescence and Chemiluminescence. 13:355-363
Evidence is provided that the amplifiers luminol and lucigenin react with different reactive oxygen species (ROS), depending on the ROS-generating system used. H2O2 is used to produce calibration curves for luminol- and lucigenin-amplified chemilumin