Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Wolfgang Jacob"'
Publikováno v:
Nuclear Materials and Energy, Vol 35, Iss , Pp 101406- (2023)
Recently we have shown that thin (33 to 55 nm) oxide films on tungsten (W) prevent deuterium (D) uptake from a low-temperature plasma (5 eV/D; 370 K; 1.4 × 1024 D/m2) into metallic W. Here we continue this investigation with higher D fluence up to 2
Externí odkaz:
https://doaj.org/article/6ab13339902641728d1dcd3d7cdc8d61
Publikováno v:
Nuclear Materials and Energy, Vol 27, Iss , Pp 100991- (2021)
We studied the uptake of deuterium (D) into tungsten (W) through thin films of W oxide. Two surface oxide films with thicknesses of 33 and 55 nm were thermally grown on W substrates. In the following, the oxidized samples were exposed to low-energy D
Externí odkaz:
https://doaj.org/article/f02c1b82555a404799f04dedfb2fc4ca
Autor:
Jean-Marie Michot, Wolfgang Jacob, Francesca Michielin, Martin Weisser, Dmitriy Zamarin, Jean-Pascal Machiels, Anna-Maria Jegg, Dominik Rüttinger, Konstanty Korski, Jean-Pierre Delord, Carlos Gomez-Roca, Tara Mitchell, Gaetan Catala, Lauriane Eberst, Michael A Cannarile, Carl Watson, Galina Babitzki, Irina Klaman, Priscila Teixeira, Sabine Hoves, Carola Ries, Georgina Meneses-Lorente, Randolph Christen, Philippe Cassier
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background This phase Ib study evaluated the safety, clinical activity, pharmacokinetics, and pharmacodynamics (PD) of emactuzumab (anti-colony stimulating factor 1 receptor monoclonal antibody (mAb)) in combination with selicrelumab (agonistic clust
Externí odkaz:
https://doaj.org/article/f591763d90694aa3ace112662e809f8f
Autor:
Michael A. Cannarile, Martin Weisser, Wolfgang Jacob, Anna-Maria Jegg, Carola H. Ries, Dominik Rüttinger
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-13 (2017)
Abstract The tumor-permissive and immunosuppressive characteristics of tumor-associated macrophages (TAM) have fueled interest in therapeutically targeting these cells. In this context, the colony-stimulating factor 1 (CSF1)/colony-stimulating factor
Externí odkaz:
https://doaj.org/article/d178a458f1254b0b92d2840ec5a6df0e
Autor:
Enriqueta Felip, Juan-Miguel Cejalvo, Wolfgang Jacob, Tania Fleitas Kanonnikoff, Alejandro Navarro Mendivil, Maria Martinez Garcia, Alvaro Taus Garcia, Natasha Leighl, Ulrik Lassen, Morten Mau-Soerensen, Celine Adessi, Francesca Michielin, Ian James, Maurizio Ceppi, Max Hasmann, Martin Weisser
Publikováno v:
ESMO Open, Vol 4, Iss 4 (2019)
Purpose This study investigated the safety and clinical activity of lumretuzumab, a humanised antihuman epidermal growth factor receptor 3 (HER3) monoclonal antibody, in combination with carboplatin and paclitaxel in first-line treatment of patients
Externí odkaz:
https://doaj.org/article/2579db173c034d929a05203fd637d4c5
Publikováno v:
C, Vol 6, Iss 1, p 3 (2020)
We applied temperature-programmed desorption (TPD) spectroscopy to study the bonding of hydrogen in amorphous hydrogenated carbon (a−C:H) films. Typical hard plasma-deposited a−C:H films with an initial hydrogen content (H/(H+C)) of about 30% wer
Externí odkaz:
https://doaj.org/article/f0440138c517450f8f76114c00efe3dd
Autor:
Denis Collins, Wolfgang Jacob, Juan Miguel Cejalvo, Maurizio Ceppi, Ian James, Max Hasmann, John Crown, Andrés Cervantes, Martin Weisser, Birgit Bossenmaier
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177331 (2017)
Bidirectional cross talk between members of the human epidermal growth factor family of receptors (HER) and the estrogen receptor (ER) is believed to underlie resistance mechanisms that develop in response to treatment with anti-HER agents and endocr
Externí odkaz:
https://doaj.org/article/6e469a908d9d4d14aeb5dc57af83056d
Autor:
Céline Adessi, Martin Weisser, Andreas Schneeweiss, Max Hasmann, Georgina Meneses-Lorente, Christine McIntyre, Fethallah Benmansour, Régine Gérard, Blandine Avignon, Sabine Wilson, Sven Kronenberg, Wolfgang Jacob, Francesca Michielin, Annie Moisan
1. Supplementary Figure 1. Illustration of tubes area detection as rectangles based on the bright field channel. 2. Supplementary Figure 2. Diarrhea severity during combination treatment with lumretuzumab (RO5479599), pertuzumab and paclitaxel in pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54db68e27685812d3371a76fa3b6a2f4
https://doi.org/10.1158/1535-7163.22505418
https://doi.org/10.1158/1535-7163.22505418
Data from Mechanistic Investigations of Diarrhea Toxicity Induced by Anti-HER2/3 Combination Therapy
Autor:
Céline Adessi, Martin Weisser, Andreas Schneeweiss, Max Hasmann, Georgina Meneses-Lorente, Christine McIntyre, Fethallah Benmansour, Régine Gérard, Blandine Avignon, Sabine Wilson, Sven Kronenberg, Wolfgang Jacob, Francesca Michielin, Annie Moisan
Combination of targeted therapies is expected to provide superior efficacy in the treatment of cancer either by enhanced antitumor activity or by preventing or delaying the development of resistance. Common challenges in developing combination therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf3ecdffdb68901e0ce6f6d3303c1fb6
https://doi.org/10.1158/1535-7163.c.6538053.v1
https://doi.org/10.1158/1535-7163.c.6538053.v1
Autor:
Ulrik N. Lassen, Martin Weisser, Birgit Bossenmaier, Francesca Michielin, Celine Adessi, Lori Steiner, Maitram Nguyen, Rajiv Dua, Suzana Vega-Harring, Ian James, Georgina Meneses-Lorente, Maurizio Ceppi, Marlene Thomas, Sabine Wilson, Jan H.M. Schellens, Sang-We Kim, Enriqueta Felip, Antonio Calles, Ji-Youn Han, Stefan Sleijfer, Maja J. De Jonge, Marlies H.G. Langenberg, Martijn P. Lolkema, Andres Cervantes, Tania Fleitas, Alvaro Taus, Maria Martinez-Garcia, Morten Mau-Sorensen, Emile E. Voest, Wolfgang Jacob, Didier Meulendijks
Purpose: This study investigated the safety, clinical activity, and target-associated biomarkers of lumretuzumab, a humanized, glycoengineered, anti-HER3 monoclonal antibody (mAb), in combination with the EGFR-blocking agents erlotinib or cetuximab i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318985d039f3af8aedc62fa7c6e52f8e
https://doi.org/10.1158/1078-0432.c.6527064.v1
https://doi.org/10.1158/1078-0432.c.6527064.v1