Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Wolfgang J Köstler"'
Autor:
Daphne Gschwantler-Kaulich, Yen Y Tan, Eva-Maria Fuchs, Gernot Hudelist, Wolfgang J Köstler, Angelika Reiner, Carmen Leser, Mohamed Salama, Johannes Attems, Christine Deutschmann, Christoph C Zielinski, Christian F Singer
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172911 (2017)
BACKGROUND:Even though trastuzumab is an effective therapy in early stage Her-2+ breast cancer, 40-50% of advanced Her-2+ breast cancer patients develop trastuzumab resistance. A potential resistance mechanism is aberrant downstream signal transmissi
Externí odkaz:
https://doaj.org/article/20f11d17673548958991b9d8d5432c0a
Autor:
Amit Zeisel, Wolfgang J Köstler, Natali Molotski, Jonathan M Tsai, Rita Krauthgamer, Jasmine Jacob‐Hirsch, Gideon Rechavi, Yoav Soen, Steffen Jung, Yosef Yarden, Eytan Domany
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-14 (2011)
Abstract Transcriptional responses to extracellular stimuli involve tuning the rates of transcript production and degradation. Here, we show that the time‐dependent profiles of these rates can be inferred from simultaneous measurements of precursor
Externí odkaz:
https://doaj.org/article/c9f4f89d361746d3a5307cf5b5df600b
Autor:
Wolfgang J Köstler, Amit Zeisel, Cindy Körner, Jonathan M Tsai, Jasmine Jacob-Hirsch, Nir Ben-Chetrit, Kirti Sharma, Hadas Cohen-Dvashi, Assif Yitzhaky, Eric Lader, Ulrich Tschulena, Gideon Rechavi, Eytan Domany, Stefan Wiemann, Yosef Yarden
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80566 (2013)
Signal-induced transcript isoform variation (TIV) includes alternative promoter usage as well as alternative splicing and alternative polyadenylation of mRNA. To assess the phenotypic relevance of signal-induced TIV, we employed exon arrays and breas
Externí odkaz:
https://doaj.org/article/8dbbe8b824c347ce9935b0151b528bff
Autor:
Ahmed A Alkhateeb, Kim Leitzel, Suhail M Ali, Cynthia Campbell-Baird, Matthew Evans, Eva-Maria Fuchs, Wolfgang J Köstler, Allan Lipton, James Connor
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51379 (2012)
Approximately half of all HER2/neu-overexpressing breast cancer patients do not respond to trastuzumab-containing therapy. Therefore, there remains an urgent and unmet clinical need for the development of predictive biomarkers for trastuzumab respons
Externí odkaz:
https://doaj.org/article/24029cb6545c4b4c9ef138c830617ed0
Autor:
Sabine Danzinger, Wolfgang J. Köstler, Martin Funovics, Merima Herac, Leonhard Müllauer, Helmut Prosch, Heinz Kölbl
Publikováno v:
Case Reports in Obstetrics and Gynecology, Vol 2019 (2019)
Lung cancer during pregnancy represents a rare disease. In this case report, we present a patient at advanced and metastasized stage of signet ring cell carcinoma who presented in the 22nd week of gestation.
Externí odkaz:
https://doaj.org/article/19cd90d12c704cada65b48016b8d7780
Autor:
Allan Lipton, John Winslow, Gordon Parry, Michael Bates, Wolfgang J. Köstler, Christian F. Singer, Eva-Maria Fuchs, Suhail M. Ali, Jodi Weidler, Kim Leitzel, Weidong Huang, Gundo Diedrich, Anasuya Saha, Elicia Penuel, Jayee Banerjee, Xueguang Jin, Jeff Sperinde
Purpose: p95HER2 is an NH2-terminally truncated form of HER2 that lacks the trastuzumab binding site and is therefore thought to confer resistance to trastuzumab treatment. In this report, we introduce a new antibody that has enabled the first direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08f29e06eab1b21289296b5307d3c685
https://doi.org/10.1158/1078-0432.c.6519126
https://doi.org/10.1158/1078-0432.c.6519126
Autor:
Allan Lipton, John Winslow, Gordon Parry, Michael Bates, Wolfgang J. Köstler, Christian F. Singer, Eva-Maria Fuchs, Suhail M. Ali, Jodi Weidler, Kim Leitzel, Weidong Huang, Gundo Diedrich, Anasuya Saha, Elicia Penuel, Jayee Banerjee, Xueguang Jin, Jeff Sperinde
CCR Translation for This Article from Quantitation of p95HER2 in Paraffin Sections by Using a p95-Specific Antibody and Correlation with Outcome in a Cohort of Trastuzumab-Treated Breast Cancer Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21498d51ffd5751c6c06e68e1e265a98
https://doi.org/10.1158/1078-0432.22442391
https://doi.org/10.1158/1078-0432.22442391
Autor:
Georg Spinka, Georg Goliasch, Henrike Arfsten, Philipp E. Bartko, Suriya Prausmüller, Guido Strunk, Markus Raderer, Christian Hengstenberg, Martin Hülsmann, Johannes Novak, Matthias Preusser, Heinz Gisslinger, Anna Cho, Gabriela Kornek, Wolfgang J. Köstler, Noemi Pavo
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine
Background: Inflammation-based scores are widely tested in cancer and have been evaluated in cardiovascular diseases including heart failure.Objectives: We investigated the impact of established inflammation-based scores on disease severity and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30711e3f1ad5c4ebd98d6a135bb662e2
https://doi.org/10.3389/fcvm.2021.725903
https://doi.org/10.3389/fcvm.2021.725903
Autor:
R. Hritcu, Walter Klepetko, Katharina Sinn, Berta Mosleh, Shahrokh Taghavi, Mir Alireza Hoda, Thomas Klikovits, Wolfgang J. Köstler
Publikováno v:
The Annals of Thoracic Surgery. 111:e45-e47
A 29-year-old woman with a primary rib osteosarcoma declined treatment and was readmitted 20 months later in life-threatening condition caused by major local tumor progression with severe mediastinal shifting, and without distant metastases. She unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269808031b3ec25b3280929a0b39e990
https://doi.org/10.1016/j.athoracsur.2020.04.116
https://doi.org/10.1016/j.athoracsur.2020.04.116
Autor:
Arno Wutzl, Hannes Kaufmann, Sasan Hamzavi, Rudolf Seemann, Muhammad Faisal, Annemarie Schratter, Sabrina Hartenbach, Claudia Lill, Boban M. Erovic, Wolfgang J. Köstler
Publikováno v:
Cancers
Cancers, Vol 12, Iss 2431, p 2431 (2020)
Cancers, Vol 12, Iss 2431, p 2431 (2020)
(1) Background: Lymphoepithelial carcinoma of the hypopharynx and larynx is a rare tumor with fewer than 50 cases in the published literature. We present a literature review to discuss the clinical findings, viral or genetic associations, diagnostic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163f80a607ba30ed93f7a85dbfd50496
https://pubmed.ncbi.nlm.nih.gov/32867094
https://pubmed.ncbi.nlm.nih.gov/32867094