Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wolfgang Heydenreuter"'
Autor:
Carolin M.-L. Gleissner, Carolin L. Pyka, Wolfgang Heydenreuter, Thomas F. Gronauer, Carina Atzberger, Vadim S. Korotkov, Weiting Cheng, Stephan M. Hacker, Angelika M. Vollmar, Simone Braig, Stephan A. Sieber
Publikováno v:
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
Externí odkaz:
https://doaj.org/article/8a702a398cd544bc9174ef6ea10e4433
Autor:
Thomas F. Gronauer, Vadim S. Korotkov, Simone Braig, Weiting Cheng, Stephan A. Sieber, Carolin L. Pyka, Angelika M. Vollmar, Carolin M.-L. Gleissner, Carina Atzberger, Wolfgang Heydenreuter, Stephan M. Hacker
Publikováno v:
ACS Central Science
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
ACS Central Science, 5 (7)
ACS Central Science, Vol 5, Iss 7, Pp 1170-1178 (2019)
ACS Central Science, 5 (7)
The natural product neocarzilin A (NCA) was discovered decades ago, and despite its potent cytotoxic effects no mode of action studies have been performed up to date. Synthesis of neocarzilins A, B, and C and a stereoisomer of NCA provided insights i
Autor:
Wolfgang Heydenreuter, Jonas Drechsel, Fritz E. Kühn, Christian Jandl, Julia Rieb, Stephan A. Sieber, David C. Mayer, Bruno Dominelli
Publikováno v:
Dalton Transactions. 46:2722-2735
The formation of different conformers of dinuclear silver(i) and gold(i) 1,1'-(2-hydroxyethane-1,1-diyl) bridge-functionalized bis(NHC) complexes with various wing-tip substituents (R = methyl, isopropyl and mesityl) has been investigated using multi
Autor:
Katharina Beck, Angelo Vedani, Wolfgang Heydenreuter, Jan Vomacka, Lydia Barth, Martin Smieško, Alex Odermatt, Petra Strajhar, Erika A. Crane, Karl Gademann, Elma Mons, Markus Neuburger, Stephan A. Sieber
To identify new potential therapeutic targets for neurodegenerative diseases, we initiated activity-based protein profiling studies with withanolide A (WitA), a known neuritogenic constituent of Withania somnifera root with unknown mechanism of actio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ce6482be808c6fa2a578d3852dd4bd
https://www.zora.uzh.ch/id/eprint/196514/
https://www.zora.uzh.ch/id/eprint/196514/
Autor:
Wolfgang Heydenreuter, Matjaz Humar, Lutz F. Tietze, Alexander Kreft, Stephan A. Sieber, Irmgard Merfort, Mehrnoush Kangani, Christian De Ford, Kamala Penchalaiah
Publikováno v:
Journal of natural products. 82(1)
Bifunctional duocarmycin analogues are highly cytotoxic compounds that have been shown to be irreversible aldehyde dehydrogenase 1 inhibitors. Interestingly, cells with low aldehyde dehydrogenase 1 expression are also sensitive to bifunctional duocar
Publikováno v:
Chemical Communications. 51:15784-15787
Falcarinol and stipudiol are natural products with potent anti-cancer activity found in several vegetables. Here, we use a chemical proteomic strategy to identify ALDH2 as a molecular target of falcarinol in cancer cells and confirm enzyme inhibition
Autor:
Wolfgang Heydenreuter, Angela Casini, Andrea Schmidt, Felix Kaiser, Fritz E. Kühn, Stephan A. Sieber, Philipp J. Altmann
Self-assembled coordination cages are interesting as drug delivery systems. Therefore, the synthesis of new ML (M = Pd, Pt) molecular cages, derived from highly fluorescent, rigid polyaromatic ligands is reported and the first PtL cage with a ligand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa75032a652131369a7981a90206753
https://orca.cardiff.ac.uk/id/eprint/94190/1/Kaiser_et_al-2016-European_Journal_of_Inorganic_Chemistry.pdf
https://orca.cardiff.ac.uk/id/eprint/94190/1/Kaiser_et_al-2016-European_Journal_of_Inorganic_Chemistry.pdf
Publikováno v:
Angewandte Chemie (International ed. in English). 56(5)
Affinity-based protein profiling (AfBPP) is a widely applied method for the target identification of bioactive molecules. Probes containing photocrosslinkers, such as benzophenones, diazirines, and aryl azides, irreversibly link the molecule of inter
Publikováno v:
Synlett. 2009:2987-2991
The transition-metal-catalyzed rearrangement of 1,1-(oligomethylene)-4-aryl-2-butene-1,4-diols was investigated. In the presence of PdCl(2)(MeCN)(2) and Cu(OTf)(2), a rapidly equilibrating 1,3-isomerization is followed by 1,2-migration to produce cyc
Autor:
Andrea Schmidt, Angela Casini, Fritz E. Kühn, Wolfgang Heydenreuter, Philipp J. Altmann, Felix Kaiser, Stephan A. Sieber
Publikováno v:
European Journal of Inorganic Chemistry. 2016:5180-5180