Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Wolfgang Heit"'
Autor:
Wolf-Karsten Hofmann, Gesine Bug, Arnold Ganser, Stefanie Wiebe, Dieter Hoelzer, Stefan Klein, Gudrun Göhring, Wolfgang Heit, Oliver G. Ottmann, Steffen Koschmieder, Felicitas Thol, Juergen Krauter, Michael Heuser, Gerd Wegener
Publikováno v:
Annals of Hematology. 93:193-202
Few studies have evaluated granulocyte colony-stimulating factor (G-CSF) priming in elderly patients with intensively treated acute myeloid leukemia (AML), and no data are available for genetically defined AML subgroups. We provide long-term results
Autor:
Hartmut Eimermacher, Norbert Niederle, Wolfgang Knauf, Leopold Balleisen, Wolfgang Heit, Dirk Megdenberg, Stefan Ibach, W. Freier, Axel Hinke, Johann Weiß
Publikováno v:
Annals of Hematology. 92:653-660
Bendamustine demonstrated clinical activity in pre-treated hematological malignancies due to its unique mechanism of action distinct from standard alkylating agents. This study assessed its efficacy in patients with chronic lymphocytic leukemia pre-t
Autor:
Gudrun Göhring, Manuela Zucknick, Kerstin Görlich, Katharina Wagner, Gerhard Heil, Arnold Ganser, Wolfram Brugger, Brigitte Schlegelberger, Aruna Raghavachar, Irina Schäfer, Lothar Kanz, Michael Heuser, Günter Schlimok, Michael Lübbert, Oliver G. Ottmann, Jürgen Krauter, Hartmut Kirchner, Walter Fiedler, Wolfgang Heit, Frederik Damm
Publikováno v:
Journal of Clinical Oncology. 28:2356-2364
Purpose We assessed the prognostic impact of IDH1 R132 mutations and a known single nucleotide polymorphism (SNP) located in the same exon of the IDH1 gene in patients with cytogenetically normal acute myeloid leukemia (CN-AML) in the context of othe
Autor:
Jürgen Krauter, Arnold Ganser, Brigitte Schlegelberger, Walter Fiedler, Frederik Damm, Hartmut Döhner, Oliver G. Ottmann, Gudrun Göhring, Wolfgang Heit, Haiyang Yun, Michael Morgan, Konstanze Döhner, Hartmut Kirchner, Günter Schlimok, Michael Heuser, Lothar Kanz, Aruna Raghavachar, Gerhard Heil, Anika Grosshennig, Michael Lübbert
Publikováno v:
Journal of Clinical Oncology. 28:578-585
Purpose We assessed the prognostic impact of a known single nucleotide polymorphism (SNP) located in the mutational hotspot of WT1 in patients with cytogenetically normal acute myeloid leukemia (CN-AML) in the context of other prognostic markers. Pat
Autor:
Donald Bunjes, B. Hertenstein, T Schmeiser, Markus Wiesneth, Renate Arnold, Wolfgang Heit, Hermann Heimpel
Publikováno v:
European Journal of Haematology. 41:243-249
Graft-versus-host disease (GvHD) prophylaxis using methotrexate (23 patients) and T-cell depletion of the graft (40 patients) was compared in 63 allogeneic bone marrow transplantations (BMT) for leukaemia. T-cell depletion significantly reduced (p =
Publikováno v:
Scandinavian Journal of Haematology. 18:105-112
The effect of polymorphonuclear granulocytes (PMN) on colony stimulating activity (CSA) was studied in double layer cultures of human Ficoll Isopaque separated white blood cells (mononuclear cells = MNC). Previously published data have been confirmed
Publikováno v:
Tissue Antigens. 14:398-406
The 51Cr release assay (CRA) is the commonly accepted technique for measurement of cell mediated cytotoxicity. This assay shows some disadvantages when mononucleated cells of human peripheral blood (MNC) are used as effector and target cells. The upt
Autor:
Michael Schaadt, Andreas Ziegler, H. Burrichter, Hartmut Kirchner, Harald Stein, Wolfgang Heit, Volker Diehl, C. Fonatsch
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 108:936-944
In the last three years, five permanently in-vitro growing cell cultures with malignant properties were established from tumour material of patients with histologically confirmed Hodgkin's disease. Four cell lines have been maintained in culture. L 4
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 112:535-541
Immunosuppressive treatment according to four different regimens was administered over the course of eight years to 42 patients with aplastic anemia. With treatment protocols which included horse-ALG and horse-ATG, remissions were achieved in most pa
Autor:
Donald Bunjes, M Wiesneth, Renate Arnold, T Schmeiser, B Anger, H. Heimpel, Wolfgang Heit, Bernd Hertenstein
Publikováno v:
DMW - Deutsche Medizinische Wochenschrift. 113:6-10
Between April 1982 and December 1986, HLA-identical bone marrow transplantations were performed on 25 patients with Philadelphia chromosome-positive chronic myelocytic leukaemia (CML), 18 in the chronic phase, 7 in acceleration or blast crisis. Twelv