Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Wolfgang Hauber"'
Autor:
Alexandra Münster, Susanne Sommer, Diana Kúkeľová, Hannes Sigrist, Eliza Koros, Serena Deiana, Klaus Klinder, Tamara Baader-Pagler, Svenja Mayer-Wrangowski, Boris Ferger, Tom Bretschneider, Christopher R. Pryce, Wolfgang Hauber, Moritz von Heimendahl
Apathy, deficiency of motivation including willingness to exert effort for reward, is a common symptom in many psychiatric and neurological disorders, including depression and schizophrenia. Despite improved understanding of the neurocircuitry and ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971a314290fac4cecbcef404ff0384c5
https://www.zora.uzh.ch/id/eprint/221202/
https://www.zora.uzh.ch/id/eprint/221202/
Autor:
Serena Deiana, Wolfgang Hauber, Alexandra Munster, Susanne Sommer, Boris Ferger, Anelise Marti, Bernhard Schmid, Cornelia Dorner-Ciossek, Holger Rosenbrock
Publikováno v:
European Journal of Pharmacology. 935:175306
N-methyl-D-aspartate-receptor (NMDAR) hypofunction contributes to cognitive impairments in neuropsychiatric disorders such as schizophrenia. Reduced NMDAR signalling can be enhanced by increasing extracellular levels of the NMDAR co-agonist glycine t
Publikováno v:
The international journal of neuropsychopharmacology. 25(3)
Pavlovian stimuli predictive of appetitive outcomes can exert a powerful influence on the selection and initiation of action, a phenomenon termed outcome-selective Pavlovian-instrumental transfer (sPIT). Rodent studies suggest that sPIT is insensitiv
Autor:
Wolfgang Hauber, Alexandra Münster
Publikováno v:
Cerebral Cortex. 28:4379-4389
The medial orbitofrontal cortex (mOFC) is known to support flexible control of goal-directed behavior. However, limited evidence suggests that the mOFC also mediates the ability of organisms to work with vigor towards a selected goal, a hypothesis th
Autor:
Wolfgang Hauber, Corinna Roschlau
Publikováno v:
Behavioural Brain Research. 323:124-132
Growing evidence suggests that the catecholamine (CA) neurotransmitters dopamine and noradrenaline support hippocampus-mediated learning and memory. However, little is known to date about which forms of hippocampus-mediated spatial learning are modul
Publikováno v:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 32
Rodent studies on effort-related responding provide a tool to analyze basal aspects of motivation and to model psychiatric motivational dysfunctions reflecting low exertion of effort or reduced behavioral activation. It turned out that dopamine (DA)
Autor:
Barbara Valastro, Wojciech Danysz, Wolfgang Hauber, Susanne Sommer, Hermann Russ, Gunnar Flik
Publikováno v:
The International Journal of Neuropsychopharmacology. 17:2045-2056
Drugs that are able to shift effort-related decision making in intact rats towards high-effort response options are largely unknown. Here, we examined the effects of two candidate drugs, MRZ-9547 and its l-enantiomer MRZ-9546 on progressive ratio (PR
Autor:
Wolfgang Hauber, Stephanie Braun
Publikováno v:
Learning & Memory. 20:700-709
Here we examined effects of acute stressors that involve either systemic coadministration of corticosterone/yohimbine (3 mg/kg each) to increase glucocorticoid/noradrenaline activity (denoted as “pharmacological” stressor) or one or several disti
Here we tested in rats effects of the procognitive drugs modafinil and methylphenidate on post-acquisition performance in an object–location paired-associates learning (PAL) task. Modafinil (32; 64 mg/kg) was without effect, while higher (9 mg/kg)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc11ab2a7d3e0efc78d55d573ed2eae
https://europepmc.org/articles/PMC4947238/
https://europepmc.org/articles/PMC4947238/
Autor:
Wolfgang Hauber, Judith Schweimer
The anterior cingulate cortex (ACC) has been implicated in encoding whether or not an action is worth performing in view of the expected benefit and the cost of performing the action. Dopamine input to the ACC may be critical for this form of effort-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8754eed471d23915cba92e7d8dfdc758
https://ora.ox.ac.uk/objects/uuid:653315d6-630a-4278-b4f6-d894f84d1b04
https://ora.ox.ac.uk/objects/uuid:653315d6-630a-4278-b4f6-d894f84d1b04