Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wolfgang Halfbrodt"'
Publikováno v:
Synlett. :0291-0294
A new stereoselective method for the synthesis of 3-sub- stituted and 2,3-disubstituted cyclopentanones is described. The key step is the 1,4-addition of a cuprate to a chilar Michael-acceptor derived from (-)-8-phenylmenthol or the Helmchen auxiliar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8643222b06505cd2708e960e14993654
https://doi.org/10.1055/s-2003-45008
https://doi.org/10.1055/s-2003-45008
Autor:
Wolfgang Halfbrodt, Karl-Heinrich Fritzemeier, Anke Müller-Fahrnow, Joachim Kuhnke, Nikolaus Heinrich, Wolfgang Schwede, Günter Neef, Klaus Schöllkopf, Ursula Egner
Publikováno v:
Tetrahedron. 55:11267-11274
The synthesis of 7α,15α-ethano bridged steroids is described. Diels-Alder reaction of 3-methoxyestra-1,3,5(10),7,14-pentaen-17-one 4 with ethylene under high pressure provides efficient synthetic access to this class of steroids. Compounds 15 and 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c59cddb66f87a9524bca4b5930466e
https://doi.org/10.1016/s0040-4020(99)00638-9
https://doi.org/10.1016/s0040-4020(99)00638-9
Autor:
Klaus Schöllkopf, Peter Muhn, Rolf Krattenmacher, Karl-Heinrich Fritzemeier, Wolfgang Halfbrodt, Eckhard Ottow, Wolfgang Schwede, Günter Neef
Publikováno v:
Steroids. 63:166-177
A synthetic approach to 11,19-bridged progestins is described. The key step in the synthesis is a 6-endo-trig radical cyclisation. The new progestins were tested for their biological activities in vitro and in vivo and compared to those of known prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::655b8d530e81f33ccd971b5562717aad
https://doi.org/10.1016/s0039-128x(97)00161-x
https://doi.org/10.1016/s0039-128x(97)00161-x
Autor:
Peter R. Schreiner, Harlmut Rehwinkel, Carlo Unvergzagt, Volkhard Austel, Heinz Stadtmüller, Wolfgang Halfbrodt, Karamali Khanbabaee, Götz Bucher, Thomas Brumby, Christoph Hoenke, Andreas Gansäuer, Karsten Krohn, Stefan Peters
Publikováno v:
Nachrichten aus Chemie, Technik und Laboratorium. 46:156-181
Das intelligente Wechselspiel zwischen HighTech-Experiment und Theorie erlaubt die immer bessere Charakterisierung reaktiver Zwischenstufen und kleiner Molekule. Schwerpunkte der metallorganischen Chemie bleiben Ubergangsmetall- und Lewissaure-kataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a13b040b13211e4ce3d4ec2b9082ff23
https://doi.org/10.1002/nadc.19980460211
https://doi.org/10.1002/nadc.19980460211
Publikováno v:
Liebigs Annalen der Chemie. 1994:885-890
A total synthesis of (±)-chokol A (rac-12) was accomplished in five steps by starting from the α,β-unsaturated ester (E)-2 in an overall yield of 24%. The key step of this synthesis is the tandem conjugate addition/Dieckmann cyclization of the cup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79a6f25cbd9cbe5d95dfc61c97ae60de
https://doi.org/10.1002/jlac.199419940907
https://doi.org/10.1002/jlac.199419940907
ChemInform Abstract: 7α,15α-Ethano Bridged Steroids. Synthesis and Progesterone Receptor Interaction
Autor:
Wolfgang Schwede, Wolfgang Halfbrodt, Nikolaus Heinrich, Ursula Egner, Karl-Heinrich Fritzemeier, Joachim Kuhnke, Klaus Dr Schoellkopf, Guenter Dr Neef, Anke Mueller-Fahrnow
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3be249379b622fe1016087e0a8d865b
https://doi.org/10.1002/chin.200002209
https://doi.org/10.1002/chin.200002209
Publikováno v:
Liebigs Annalen der Chemie. 1992:351-355
allo-Coronamic acid (1) was synthesized in five steps enantiomerically and diastereomerically virtually pure by starting from the bislactim ethers of cyclo(-L-Val-Gly-) (3a) or cyclo-(-L-tert-Leu-Gly-) (3b) in an overall yield of 31%. The key step of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::528feff2f07948e745585f10e52b5475
https://doi.org/10.1002/jlac.199219920162
https://doi.org/10.1002/jlac.199219920162
Publikováno v:
ChemInform. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddb3fc401d7793d225cf2d45e388b176
https://doi.org/10.1002/chin.200424078
https://doi.org/10.1002/chin.200424078