Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Wolfgang H. Dillmann"'
Autor:
Hong Gao, Ke Wang, Jorge A. Suarez, Zhongmou Jin, Karina Cunha e Rocha, Dinghong Zhang, Andrea Farrell, Tyler Truong, Yasemin Tekin, Breanna Tan, Hyun Suh Jung, Julia Kempf, Sushil K. Mahata, Wolfgang H. Dillmann, Jorge Suarez, Wei Ying
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Emerging evidence indicates the critical roles of microbiota in mediating host cardiac functions in ageing, however, the mechanisms underlying the communications between microbiota and cardiac cells during the ageing process have not been fully eluci
Externí odkaz:
https://doaj.org/article/1cefea9975c845caa6507fbb179e7452
Autor:
Hong Gao, Zhongmou Jin, Kechun Tang, Yudong Ji, Jorge Suarez, Jorge A. Suarez, Karina Cunha e Rocha, Dinghong Zhang, Wolfgang H. Dillmann, Sushil K. Mahata, Wei Ying
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 4 (2022)
Background Obesity is an established risk factor for hypertension. Although obesity‐induced gut barrier breach leads to the leakage of various microbiota‐derived products into host circulation and distal organs, the roles of microbiota in mediati
Externí odkaz:
https://doaj.org/article/6cd3daeab6994496b8c1228c335b0c02
Autor:
Mei Hua Gao, PhD, N. Chin Lai, PhD, Dimosthenis Giamouridis, MSc, Young Chul Kim, PhD, Zhen Tan, PhD, Tracy Guo, BS, Wolfgang H. Dillmann, MD, Jorge Suarez, PhD, H. Kirk Hammond, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 7, Pp 617-629 (2016)
Transgenic mice with cardiac-directed C1C2, a fusion protein of the intracellular C1 and C2 segments of adenylyl cyclase type 6, had normal left ventricular (LV) function, but diminished cAMP generation. Cardiac myocytes from C1C2 mice showed increas
Externí odkaz:
https://doaj.org/article/c3d4b2955ed24706befb04be3dee1927
Autor:
Przemysław B. Radwański, PharmD, PhD, Hsiang-Ting Ho, PhD, Rengasayee Veeraraghavan, PhD, Lucia Brunello, PhD, Bin Liu, PhD, Andriy E. Belevych, PhD, Sathya D. Unudurthi, PhD, Michael A. Makara, PhD, Silvia G. Priori, MD, PhD, Pompeo Volpe, PhD, Antonis A. Armoundas, PhD, Wolfgang H. Dillmann, MD, Bjorn C. Knollmann, MD, PhD, Peter J. Mohler, PhD, Thomas J. Hund, PhD, Sándor Györke, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 1, Iss 4, Pp 251-266 (2016)
Although triggered arrhythmias including catecholaminergic polymorphic ventricular tachycardia (CPVT) are often caused by increased levels of circulating catecholamines, the mechanistic link between β-adrenergic receptor (AR) stimulation and the sub
Externí odkaz:
https://doaj.org/article/14f969abcf034b40ad9a83088e11255d
Autor:
Bin Liu, Qing Lou, Heather Smith, Florencia Velez-Cortes, Wolfgang H. Dillmann, Björn C. Knollmann, Antonis A. Armoundas, Sándor Györke
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2535 (2020)
Ryanodine receptor 2 (RyR2) and SERCA2a are two major players in myocyte calcium (Ca) cycling that are modulated physiologically, affected by disease and thus considered to be potential targets for cardiac disease therapy. However, how RyR2 and SERCA
Externí odkaz:
https://doaj.org/article/9d165d77cf114964a9d79a319e74625b
Autor:
Yusu Gu, Darren E. Casteel, Shunhui Zhuang, Nancy D. Dalton, Gerburg K. Schwaerzer, Wolfgang H. Dillmann, Renate B. Pilz, Federico Cividini, Hema Kalyanaraman, Kirk L. Peterson, Gerry R. Boss
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Heart failure is associated with high morbidity and mortality, and new therapeutic targets are needed. Preclinical data suggest that pharmacological activation of protein kinase G (PKG) can reduce maladaptive ventricular remod
Autor:
Wolfgang H. Dillmann, Anzhi Dai, Jorge Suarez, Federico Cividini, Christopher Benner, Jorge A. Suarez, Darren E. Casteel, Tanja Diemer, Majid Ghassemian, Sven Heinz, Brian T. Scott
Publikováno v:
Diabetes
Diabetes, vol 70, iss 3
Diabetes, vol 70, iss 3
The contribution of altered mitochondrial Ca2+ handling to metabolic and functional defects in type 2 diabetic (T2D) mouse hearts is not well understood. In this study, we show that the T2D heart is metabolically inflexible and almost exclusively dep
Autor:
Manoja K. Brahma, Chase A. Andrizzi, Renata O. Pereira, E. Dale Abel, Wayne E. Bradley, Oleh Khalimonchuk, John C. Schell, Ariel Contreras-Ferrat, Curtis D. Olsen, Adam R. Wende, Chae-Myeong Ha, Li Wang, Sheldon E. Litwin, Hansjörg Schwertz, Louis J. Dell'Italia, Joseph Tuinei, Wolfgang H. Dillmann, Mark E Pepin
Publikováno v:
Diabetes
Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is unclear whether these changes are adaptive or maladaptive. To directly evaluate the relation
Autor:
Wolfgang H Dillmann, Majid Ghassemian, Christopher W Benner, Jorge A Suarez, Tanja Diemer, Anzhi Dai, Sven Heinz, Darren E. Casteel, Jorge Suarez, Brian T Scott, Federico Cividini, Ada Admin
The contribution of altered mitochondrial Ca2+ handling to metabolic and functional defects in type 2 diabetic (T2D) mouse hearts is not well understood. Here, we show that the T2D heart is metabolically inflexible and almost exclusively dependent on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1df2a6cba74393b03d680a7ecf6cd09c
https://doi.org/10.2337/figshare.13342229
https://doi.org/10.2337/figshare.13342229
Autor:
E. Dale Abel, Sheldon E. Litwin, Wolfgang H. Dillmann, Louis J. Dell’Italia, Wayne E. Bradley, Curtis D. Olsen, Chase A. Andrizzi, Li Wang, Ariel Contreras-Ferrat, Joseph Tuinei, Manoja K. Brahma, Renata O. Pereira, Hansjörg Schwertz, Oleh Khalimonchuk, Mark E. Pepin, Chae-Myeong Ha, John C. Schell, Adam R. Wende, Ada Admin
Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is unclear if these changes are adaptive or maladaptive. To directly evaluate the relationship
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a85d3d87c39e528a57c735e4d2fca2d
https://doi.org/10.2337/figshare.12200918
https://doi.org/10.2337/figshare.12200918