Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Wolfgang G Kreyling"'
Autor:
Lin Yang, Qiongliang Liu, Pramod Kumar, Arunima Sengupta, Ali Farnoud, Ruolin Shen, Darya Trofimova, Sebastian Ziegler, Neda Davoudi, Ali Doryab, Ali Önder Yildirim, Markus E. Diefenbacher, Herbert B. Schiller, Daniel Razansky, Marie Piraud, Gerald Burgstaller, Wolfgang G. Kreyling, Fabian Isensee, Markus Rehberg, Tobias Stoeger, Otmar Schmid
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Targeted (nano-)drug delivery is essential for treating respiratory diseases, which are often confined to distinct lung regions. However, spatio-temporal profiling of drugs or nanoparticles (NPs) and their interactions with lung macrophages
Externí odkaz:
https://doaj.org/article/09230b937a684643ae6ba3af933a693d
Autor:
Winfried Möller, Uwe Schuschnig, Gülnaz Celik, Wolfgang Münzing, Peter Bartenstein, Karl Häussinger, Wolfgang G Kreyling, Martin Knoch, Martin Canis, Sven Becker
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74991 (2013)
ObjectivesChronic rhinosinusitis (CRS) is a common chronic disease of the upper airways and has considerable impact on quality of life. Topical delivery of drugs to the paranasal sinuses is challenging, therefore the rate of surgery is high. This stu
Externí odkaz:
https://doaj.org/article/928310112b434f988a85b98334e75b78
Autor:
Wei-Chun Chou, Yi-Hsien Cheng, Jim E. Riviere, Nancy A. Monteiro-Riviere, Wolfgang G. Kreyling, Zhoumeng Lin
Publikováno v:
Particle and Fibre Toxicology, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Physiologically based pharmacokinetic (PBPK) modeling is an important tool in predicting target organ dosimetry and risk assessment of nanoparticles (NPs). The methodology of building a multi-route PBPK model for NPs has not been
Externí odkaz:
https://doaj.org/article/aa10cf438b8d48268b72ca7a3f8e47b2
Autor:
Wolfgang G. Kreyling, Uwe Holzwarth, Carsten Schleh, Stephanie Hirn, Alexander Wenk, Martin Schäffler, Nadine Haberl, Manuela Semmler-Behnke, Neil Gibson
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-27 (2019)
Abstract Background Industrially produced quantities of TiO2 nanoparticles are steadily rising, leading to an increasing risk of inhalation exposure for both professionals and consumers. Particle inhalation can result in inflammatory and allergic res
Externí odkaz:
https://doaj.org/article/9a743851ebd24a069e0268b21eb6a7af
Autor:
Koustav Ganguly, Dariusch Ettehadieh, Swapna Upadhyay, Shinji Takenaka, Thure Adler, Erwin Karg, Fritz Krombach, Wolfgang G. Kreyling, Holger Schulz, Otmar Schmid, Tobias Stoeger
Publikováno v:
Particle and Fibre Toxicology, Vol 14, Iss 1, Pp 1-17 (2017)
Abstract Background The death toll associated with inhaled ambient particulate matter (PM) is attributed mainly to cardio-vascular rather than pulmonary effects. However, it is unclear whether the key event for cardiovascular impairment is particle t
Externí odkaz:
https://doaj.org/article/0ff2c684a8854b1d88d863f13e13f576
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
In recent animal experiments with suspensions of radiolabeled TiO2 nanoparticles large and highly variable radioactivity fractions were retained in disposable plastic syringes. After unloading between 10% and up to 70% of the loaded dose were still p
Externí odkaz:
https://doaj.org/article/851de270db3143448b90fe04f1a4b83d
Autor:
Sebastian Ahlberg, Alexandra Antonopulos, Jörg Diendorf, Ralf Dringen, Matthias Epple, Rebekka Flöck, Wolfgang Goedecke, Christina Graf, Nadine Haberl, Jens Helmlinger, Fabian Herzog, Frederike Heuer, Stephanie Hirn, Christian Johannes, Stefanie Kittler, Manfred Köller, Katrin Korn, Wolfgang G. Kreyling, Fritz Krombach, Jürgen Lademann, Kateryna Loza, Eva M. Luther, Marcelina Malissek, Martina C. Meinke, Daniel Nordmeyer, Anne Pailliart, Jörg Raabe, Fiorenza Rancan, Barbara Rothen-Rutishauser, Eckart Rühl, Carsten Schleh, Andreas Seibel, Christina Sengstock, Lennart Treuel, Annika Vogt, Katrin Weber, Reinhard Zellner
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 1944-1965 (2014)
PVP-capped silver nanoparticles with a diameter of the metallic core of 70 nm, a hydrodynamic diameter of 120 nm and a zeta potential of −20 mV were prepared and investigated with regard to their biological activity. This review summarizes the phys
Externí odkaz:
https://doaj.org/article/9ff9b4c808fe4650a9603784c6b22761
Autor:
Wolfgang G. Kreyling, Stefanie Fertsch-Gapp, Martin Schäffler, Blair D. Johnston, Nadine Haberl, Christian Pfeiffer, Jörg Diendorf, Carsten Schleh, Stephanie Hirn, Manuela Semmler-Behnke, Matthias Epple, Wolfgang J. Parak
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 5, Iss 1, Pp 1699-1711 (2014)
When particles incorporated within a mammalian organism come into contact with body fluids they will bind to soluble proteins or those within cellular membranes forming what is called a protein corona. This binding process is very complex and highly
Externí odkaz:
https://doaj.org/article/2b9eec8e923e48f1ae5e9227fe6d25b3
Autor:
Nadine Haberl, Stephanie Hirn, Alexander Wenk, Jörg Diendorf, Matthias Epple, Blair D. Johnston, Fritz Krombach, Wolfgang G. Kreyling, Carsten Schleh
Publikováno v:
Beilstein Journal of Nanotechnology, Vol 4, Iss 1, Pp 933-940 (2013)
Silver nanoparticles (AgNP) are among the most promising nanomaterials, and their usage in medical applications and consumer products is growing rapidly. To evaluate possible adverse health effects, especially to the lungs, the current study focused
Externí odkaz:
https://doaj.org/article/4308fd00125344619caa36dc08835715
Autor:
Albert Duschl, Masakazu Umezawa, Naomi Hisanaga, Alison Elder, Iseult Lynch, Uschi M. Graham, Flemming R. Cassee, Takahiro Kobayashi, Daniele Zink, Sahoko Ichihara, Sally S. Tinkle, Michael Riediker, Mary Gulumian, Wolfgang G. Kreyling, Richard D. Handy, Günter Oberdörster, Gaku Ichihara, Tsun-Jen Cheng
Publikováno v:
Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-33 (2019)
Particle and Fibre Toxicology
Particle and Fibre Toxicology
Background Particles and fibres affect human health as a function of their properties such as chemical composition, size and shape but also depending on complex interactions in an organism that occur at various levels between particle uptake and targ