Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Wolfgang Erl"'
Publikováno v:
Journal of Cellular Physiology. 204:881-888
n-3 polyunsaturated fatty acids (PUFAs) have been shown to exert beneficial effects in the prevention of cardiovascular disease, inflammation, and on tumor growth. To investigate effects of PUFAs on proliferation and apoptosis in endothelial cells, w
Publikováno v:
Blood. 104:2761-2766
Endothelial progenitor cells (EPCs) play a role in the repair of ischemic or injured tissue. Because endothelial injury can be associated with apoptosis, we have investigated whether apoptotic bodies from mature endothelial cells (ECs) may affect gro
Autor:
Wolfgang Erl, Christian Weber, Ute Zeiffer, Elisa A. Liehn, Andreas Schober, Michael Lietz, Neil Emans, Zhong-qun Yan
Publikováno v:
Circulation Research. 94:776-784
Leukocyte recruitment is crucial for the response to vascular injury in spontaneous and accelerated atherosclerosis. Whereas the mechanisms of leukocyte adhesion to endothelium or matrix-bound platelets have been characterized, less is known about th
Autor:
Wolfgang Erl, Dharmendra Pandey, Nadine Haserück, Catherine Ravanat, Philippe Ohlmann, Gabor Tigyi, Wolfgang Siess, Christian Gachet
Publikováno v:
Blood. 103:2585-2592
Despite the fact that lysophosphatidic acid (LPA) has been identified as a main platelet-activating lipid of mildly oxidized low-density lipoprotein (LDL) and human atherosclerotic lesions, it remains unknown whether it is capable of activating plate
Publikováno v:
Biochemical and Biophysical Research Communications. 307:322-326
Prostaglandins are a family of structurally related molecules formed by many cells in response to extrinsic stimuli. A member of this family, 15-deoxy-Delta(12,14)-PGJ(2) (15d-PGJ(2)), shows unique biological properties including anti-inflammatory, a
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 23:1185-1189
Postnatal bone marrow contains a subtype of progenitor cells that have the capacity to migrate to the peripheral circulation and to differentiate into mature endothelial cells. Therefore, these cells have been termed endothelial progenitor cells (EPC
Publikováno v:
Trends in Cardiovascular Medicine. 13:201-206
Bone marrow of adults contains a subtype of progenitor cells that have the capacity to differentiate into mature endothelial cells and have therefore been termed endothelial progenitor cells (EPCs). Of the three cell markers (CD133, CD34, and the vas
Publikováno v:
American Journal of Physiology-Cell Physiology. 278:C1116-C1125
Pyrrolidine dithiocarbamate (PDTC) has been found to induce or inhibit apoptosis in different cell types. Here we show that PDTC dose-dependently reduced the viability of rat smooth muscle cells (rSMC), human fibroblasts, and endothelial cells at low
Publikováno v:
Blood. 93:3685-3693
Mobilization of nuclear factor-κB (NF-κB) activates transcription of genes encoding endothelial adhesion molecules and chemokines that contribute to monocyte infiltration critical in atherogenesis. Inhibition of NF-κB has been achieved by pharmaco
Publikováno v:
Biochemical Pharmacology. 52:433-439
The thrombospondin and collagen receptor CD36 was recently found to function, also, as a dominating scavenger receptor for oxidized low-density lipoproteins (oxLDL). Thus, CD36 might be a key factor in monocyte adhesion and foam cell formation. We, t