Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Wolfgang Driever"'
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
Catecholaminergic neuron clusters are among the most conserved neuromodulatory systems in vertebrates, yet some clusters show significant evolutionary dynamics. Because of their disease relevance, special attention has been paid to mammalian midbrain
Externí odkaz:
https://doaj.org/article/762f1904da2441148661e320f2433912
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Wnt/β-catenin signaling contributes to patterning, proliferation, and differentiation throughout vertebrate neural development. Wnt/β-catenin signaling is important for mammalian midbrain dopaminergic neurogenesis, while little is known ab
Externí odkaz:
https://doaj.org/article/f373bb340c8c46aa88c5eefb4b0986d5
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
The hypothalamus is characterized by great neuronal diversity, with many neuropeptides and other neuromodulators being expressed within its multiple anatomical domains. The regulatory networks directing hypothalamic development have been studied in d
Externí odkaz:
https://doaj.org/article/f007fffe62634fd4b5a4e87f97bb0d56
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
The cell type diversity and complexity of the nervous system is generated by a network of signaling events, transcription factors, and epigenetic regulators. Signaling and transcriptional control have been easily amenable to forward genetic screens i
Externí odkaz:
https://doaj.org/article/7f19328e4ff5424f893db77d7bd2d223
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Analyses of genoarchitecture recently stimulated substantial revisions of anatomical models for the developing hypothalamus in mammalian and other vertebrate systems. The prosomeric model proposes the hypothalamus to be derived from the secondary pro
Externí odkaz:
https://doaj.org/article/23eee93f769f48aca50dee09a4a0606e
Autor:
Melanie Haehnel-Taguchi, António M. Fernandes, Margit Böhler, Ina Schmitt, Lena Tittel, Wolfgang Driever
Publikováno v:
Frontiers in Neuroanatomy, Vol 12 (2018)
Dopaminergic neurons of the descending diencephalospinal system are located in the posterior tuberculum (PT) in zebrafish (Danio rerio), and correspond in mammals to the A11 group in hypothalamus and thalamus. In the larval zebrafish, they are likely
Externí odkaz:
https://doaj.org/article/7d17b961090649c6951e1c285d30aa6a
Publikováno v:
Biology Open, Vol 2, Iss 8, Pp 845-854 (2013)
Summary Epiboly is the first coordinated cell movement in most vertebrates and marks the onset of gastrulation. During zebrafish epiboly, enveloping layer (EVL) and deep cells spread over the vegetal yolk mass with a concomitant thinning of the deep
Externí odkaz:
https://doaj.org/article/3fc8578ff12744e781b5d1f33a0cfc9a
Autor:
Daria Onichtchouk, Florian Geier, Bozena Polok, Daniel M Messerschmidt, Rebecca Mössner, Björn Wendik, Sungmin Song, Verdon Taylor, Jens Timmer, Wolfgang Driever
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-18 (2010)
Abstract The transcription factor POU5f1/OCT4 controls pluripotency in mammalian ES cells, but little is known about its functions in the early embryo. We used time‐resolved transcriptome analysis of zebrafish pou5f1 MZspg mutant embryos to identif
Externí odkaz:
https://doaj.org/article/54cc733a74a64329b7d01809ed199e7b
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0134299 (2015)
DNA damage-binding protein 1 (DDB1) is a large subunit of the heterodimeric DDB complex that recognizes DNA lesions and initiates the nucleotide excision repair process. DDB1 is also a component of the CUL4 E3 ligase complex involved in a broad spect
Externí odkaz:
https://doaj.org/article/6ff532d43e7c49d0a55093f84bc38e33
Autor:
Kay Kotkamp, Esther Kur, Björn Wendik, Bożena K Polok, Shifra Ben-Dor, Daria Onichtchouk, Wolfgang Driever
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92356 (2014)
Myc proteins control cell proliferation, cell cycle progression, and apoptosis, and play important roles in cancer as well in establishment of pluripotency. Here we investigated the control of myc gene expression by the Pou5f1/Oct4 pluripotency facto
Externí odkaz:
https://doaj.org/article/d320406fcb6d45369a2ea83a44bf49b3