Výsledky vyhledávání - "Wolfgang Dillenburg"

Activation of P-glycoprotein (Pgp)-mediated drug efflux by extracellular acidosis: in vivo imaging with 68Ga-labelled PET tracer

Autor: Frank Rösch, Marco Fellner, Nicole Bausbacher, Hans-Georg Buchholz, Mathias Schreckenberger, Wolfgang Dillenburg, Oliver Thews

Publikováno v: European Journal of Nuclear Medicine and Molecular Imaging. 37:1935-1942

In vitro it has been shown that the functional activity of P-glycoprotein (Pgp), an important drug transporter responsible for multidrug resistance, can be strongly increased by extracellular acidosis. Here mitogen-activated protein kinases (MAPK) (p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cab6f20dc719c1bc5cdf4592f6f0f26
https://doi.org/10.1007/s00259-010-1504-3

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Laparoscopic Radical Prostatectomy in Men Older than 70 Years of Age with Localized Prostate Cancer: Comparison of Morbidity, Reconvalescence, and Short-Term Clinical Outcomes between Younger and Older Men

Autor: Eduard Becht, Rachelle de Vries, Vassilis Poulakis, Ulrich Witzsch, Wolfgang Dillenburg

Publikováno v: European Urology. 51:1341-1349

To analyze the safety and efficacy of extraperitoneal laparoscopic radical prostatectomy (eL-RPE) in elderly versus younger men with localized prostate cancer.Patients undergoing eL-RPE were retrospectively subdivided into group eL-RPE1 (72 men aged

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7869737de4bfa012f30896b4319692cf
https://doi.org/10.1016/j.eururo.2006.12.013

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Vesicourethral anastomosis during endoscopic extraperitoneal radical prostatectomy: A prospective comparison between the single-knot running and interrupted technique

Autor: Vassilis, Poulakis, Konstantinos, Skriapas, Rachelle, de Vries, Wolfgang, Dillenburg, Ulrich, Witzsch, Eduard, Becht

Publikováno v: Urology. 68:1284-1289

To determine the safety and efficacy of the single-knot running versus interrupted technique for urethrovesical anastomosis during endoscopic extraperitoneal radical prostatectomy.A total of 250 consecutive patients who underwent endoscopic extraperi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268edf6eca569e371528e246cb7567b0
https://doi.org/10.1016/j.urology.2006.08.1063

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Laparoscopic Radical Prostatectomy: Impact of Modified Apical and Posterolateral Dissection In Reduction of Positive Surgical Margins in Patients with Clinical Stage T2 Prostate Cancer and High Risk of Extracapsular Extension

Autor: Eduard Becht, Hans-Michael Altmansberger, Rachelle de Vries, Vassilis Poulakis, Wolfgang Dillenburg

Publikováno v: Journal of Endourology. 20:332-339

To determine whether modifications of extraperitoneal endoscopic radical prostatectomy (EERP) reduce the rate of a positive surgical margin (PSM) in men with clinical stage T(2) prostate cancer and a high risk of extracapsular extension.A consecutive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f47dbecd0c536af2a60e5a5276bd8592
https://doi.org/10.1089/end.2006.20.332

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Tension-Free Vaginal Tape (TVT) in Morbidly Obese Patients with Severe Urodynamic Stress Incontinence as Last Option Treatment

Autor: Ulrich Witzsch, Michael D. Melekos, Konstantinos Skriapas, Eduard Becht, Rachelle de Vries, Vassilis Poulakis, Wolfgang Dillenburg

Publikováno v: European Urology. 49:544-550

To determine the safety and efficacy of tension-free vaginal tape (TVT) in morbidly obese women with severe urodynamic stress incontinence (USI) as last option treatment.Thirty-one patients with body mass index (BMI)40 kg/m2, who had undergone the TV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1e4c0438f603f5618b6e3b6f181c7a
https://doi.org/10.1016/j.eururo.2005.11.008

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Retroperitoneoscopic Versus Open Surgical Radical Nephrectomy for Large Renal Cell Carcinoma in Clinical Stage cT2 or cT3a: Quality of Life, Pain and Reconvalescence

Autor: Vassilis Poulakis, E. Becht, Michael D. Melekos, Rachelle de Vries, Ulrich Witzsch, Konstantinos Skriapas, Nikolaos Ferakis, Wolfgang Dillenburg

Publikováno v: European Urology. 49:314-323

To determine whether retroperitoneoscopic radical nephrectomy for large renal cell carcinoma in stage cT2 or cT3a is a feasible, safe and effective therapy option and if it shows any advantage regarding quality of life in comparison to open procedure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3b970d4a0fed7a3077c29caaf6fd75d
https://doi.org/10.1016/j.eururo.2005.10.021

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Laparoscopic Radical Prostatectomy Using an Extraperitoneal Approach: Nordwest Hospital Technique and Initial Experience in 255 Cases

Autor: Ulrich Witzsch, Rachelle de Vries, Eduard Becht, Nikolaos Ferakis, Vassilis Poulakis, Wolfgang Dillenburg

Publikováno v: Journal of Endourology. 20:45-53

We report on our modifications in technique and initial experience with 255 extraperitoneal laparoscopic radical prostatectomy (eLRP).Using significant surgical modifications, our laparoscopic method replicates the steps of the retropubic descending

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d4717993aadf600b799c766018c69d
https://doi.org/10.1089/end.2006.20.45

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Laparoscopic Radical Prostatectomy: The Value of Intraoperative Frozen Sections

Autor: Vasileios Poulakis, Ulrich Witzsch, Eduard Becht, Rachelle de Vries, Hans-Michael Altmansberger, Konstantinos Skriapas, Wolfgang Dillenburg

Publikováno v: European Urology. 48:614-621

Objective: To examine the clinical and pathological value of intraoperative frozen section (IFS) in patients undergoing laparoscopic radical prostatectomy (L-RPE) for clinically localized prostate cancer. Methods: The study includes 198 consecutive c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a0456515d83d6fab33e55ac8e1264c
https://doi.org/10.1016/j.eururo.2005.06.015

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PET imaging of the impact of extracellular pH and MAP kinases on the p-glycoprotein (Pgp) activity

Autor: Oliver, Thews, Wolfgang, Dillenburg, Frank, Rösch, Marco, Fellner

Publikováno v: Advances in experimental medicine and biology. 765

The functional activity of p-glycoprotein (Pgp) can be increased in vitro by an extracellular acidosis via activation of MAP kinases (p38, ERK1/2). In order to study these effects in vivo a new (68)Ga-labeled PET tracer was developed which serves as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15312360399a07bdc8de8d965300a2f9
https://pubmed.ncbi.nlm.nih.gov/22879045

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