Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Wolfgang Berthold"'
Autor:
Pascal Bailon, Wolfgang Berthold
Publikováno v:
Pharmaceutical Science & Technology Today. 1:352-356
Polyethylene glycol (PEG)-conjugated proteins belong to a new class of biomolecules that are neither proteins nor polymers, but which are hybrids of the two. PEG conjugation of biopharmaceuticals is now common practice in efforts to achieve sustained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ea4396aeef616f0c1b73cf780217d60
https://doi.org/10.1016/s1461-5347(98)00086-8
https://doi.org/10.1016/s1461-5347(98)00086-8
Autor:
William Werz, Wolfgang Berthold, Günther Jung, Rolf G. Werner, Michael Schlüter, Frank Gombert, Anja Bayer
Publikováno v:
Biological Chemistry Hoppe-Seyler. 375:471-480
The first defined sequential epitope of the tissue plasminogen activator (t-PA) was determined by a monoclonal antibody against a synthetic peptide segment corresponding to peptide sequence 341-354 of t-PA. This segment was selected by computer assis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550c2c938058b8d819f7639de3623d3e
https://doi.org/10.1515/bchm3.1994.375.7.471
https://doi.org/10.1515/bchm3.1994.375.7.471
Publikováno v:
Protein Protocols Handbook, The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d04152df3fa97193313d4e0aa647390
https://doi.org/10.1385/1-59259-169-8:1059
https://doi.org/10.1385/1-59259-169-8:1059
Autor:
Jill E. Porter, Wolfgang Berthold, and Adrienne Farid, Carol Ann Schaffer, Pascal Bailon, Mary Graves, Marlene W. Modi, Wen Pan, Cheryl Spence, Zhi-Xin Xu, Palleroni Alicia Vallejo, George Ehrlich, Wen-Jian Fung
Publikováno v:
Bioconjugate chemistry. 12(2)
A potent, long-lasting form of interferon alpha-2a mono-pegylated with a 40 kilodalton branched poly(ethylene glycol) was designed, synthesized, and characterized. Mono-pegylated interferon alpha-2a was comprised of four major positional isomers invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49613ec77737afdf03f09df70646580f
https://pubmed.ncbi.nlm.nih.gov/11312680
https://pubmed.ncbi.nlm.nih.gov/11312680
Publikováno v:
Methods in Molecular Biology ISBN: 9780896036949
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cece026cb78db89e441bb18248c2498
https://doi.org/10.1007/978-1-60327-261-2_18
https://doi.org/10.1007/978-1-60327-261-2_18
The metabolic characteristics of three different cell types, one hybridoma and two CHO cell lines, were investigated. The results indicate a strictly specific demand of the cells for appropriate nutrient supplementation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bc2af92bff716a48cf1d9d1c757da86
https://doi.org/10.1016/b978-0-7506-1845-8.50048-x
https://doi.org/10.1016/b978-0-7506-1845-8.50048-x
Autor:
Wolfgang Berthold
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 21(2)
The safety of a patient who is the recipient of protein drugs has to be assured. A "wrong" protein is thought to represent a great risk. The philosophy of testing strategies related to gene stability with product safety will be discussed in the light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ee957a0c597e9f65a9ff9dd53919f5
https://pubmed.ncbi.nlm.nih.gov/8297607
https://pubmed.ncbi.nlm.nih.gov/8297607