Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Wolfgang A. Kroll"'
Autor:
Wolfgang R. Kroll
Publikováno v:
International Zoo Yearbook. 4:131-140
Publikováno v:
Biochemical Medicine. 10:368-373
Methodology for the preparation of cultured fibroblasts for measurement of their free (nonprotein) amino acids was studied in two ways. First, the effect of storage of fibroblasts at −20°C, −70°C, and −196°C was investigated. The recovery of
Autor:
Jerry A. Schneider, Wolfgang A. Kroll
Publikováno v:
Clinics in Endocrinology and Metabolism. 3:57-69
Summary Cystinosis is a recessively inherited metabolic disorder characterised biochemically by a high intracellular content of free (non-protein) cystine which results in crystal deposition in the cornea, conjunctiva, bone marrow, lymph nodes, leuco
Autor:
Wolfgang A. Kroll, Gerald S. Spear, F. L. A. Becker, A. J. Garvin, C. Jacobson, E O Horger rd, V. G. Wong, Jerry A. Schneider, F. M. Verroust, Ocean L. Pellett
Publikováno v:
The New England journal of medicine. 290(16)
We diagnosed cystinosis in an 18-week-old fetus on the basis of an increased content of nonprotein cystine in cultured amniotic-fluid cells. These cells did not contain cystine crystals, a...
Autor:
Stanley A. Mendoza, Alfred D. Godfrey, James J. Schlesselman, Jerry A. Schneider, Jess G. Thoene, Sheldon Orloff, Wolfgang A. Kroll, Joseph D. Schulman
Publikováno v:
The New England journal of medicine. 300(14)
Because high concentrations of ascorbic acid (0.57 mM) lower the free (nonprotein) cystine content of cultured cystinotic skin fibroblasts by over 50 per cent, we did a double-blind clinical trial to establish whether this drug would benefit cystinot
Autor:
Wolfgang A. Kroll, Jerry A. Schneider
Publikováno v:
Science (New York, N.Y.). 186(4168)
The 100-fold increase in free cystine content characteristic of cultured skin fibroblasts from patients with nephropathic cystinosis was decreased more than 50 percent by addition of L-ascorbic acid to the culture medium at concentrations of 0.29 to
Autor:
Gerald S. Spear, A. J. Garvin, F. L. A. Becker, E. O. Horger, V. G. Wong, Ocean L. Pellett, F. M. Verroust, Wolfgang A. Kroll, C. Jacobson, Jerry A. Schneider
Publikováno v:
Obstetrical & Gynecological Survey. 29:618-619
Autor:
Wolfgang A. Kroll, Jerry A. Schneider
Publikováno v:
Pediatric Research. 8:390-390
Ascorbic acid (0.57 mM) caused a slow decline in the free (acid-soluble) cystine content of skin fibroblasts from 6 cystinotic patients of 58.6% (range 48-75%) over a 3 day period. The cystine content then remained at this level as long as ascorbic a