Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Wolfgang Tomek"'
This study reveals that cultivation of preantral and early antral (< 500 μm) follicles in culture medium containing FCS results in an expression of cytochrome P450 arom. (aromatase). The enzymatic activity of aromatase, measured in terms of the estr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0d59ba0b47490b8b417525e4890339
https://www.arch-anim-breed.net/49/29/2006/
https://www.arch-anim-breed.net/49/29/2006/
Publikováno v:
Molecular Reproduction and Development. 81:363-375
SUMMARY The mammalian target of rapamycin (mTor), a Ser/Thr protein kinase, is implicated in the phosphorylation-triggered inactivation of translation repressors, the so-called eukaryotic initiation factor 4E (eIF4E)-binding proteins (4E-BPs). Previo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d36618535509db2cbb76df0074d9b2d
https://doi.org/10.1002/mrd.22305
https://doi.org/10.1002/mrd.22305
Publikováno v:
Reproductive Biology. 13:184-194
Recently we showed that essential components for the initiation of protein synthesis, namely the eukaryotic initiation factor 4E (eIF4E, mRNA-cap-binding protein) and its repressors 4E-BP1 as well as 4E-BP2, are proteolytically processed in the porci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8231814ed52de143aacccbb906b01dd6
https://doi.org/10.1016/j.repbio.2013.06.001
https://doi.org/10.1016/j.repbio.2013.06.001
Publikováno v:
Molecular Reproduction and Development. 79:767-776
Recently, we identified an N-terminally truncated form of the mRNA cap binding protein eIF4E in the porcine luminal epithelium during implantation. EIF4E truncation is accompanied by degradation of the eIF4E-repressor protein 4E-BP1. In this study, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73805e2bf2b470ddb5a519039c34dceb
https://doi.org/10.1002/mrd.22108
https://doi.org/10.1002/mrd.22108
Autor:
Wolfgang Tomek, K. Wollenhaupt
Publikováno v:
Animal Reproduction Science. 134:2-8
Translational control is particularly important in situations where the correlation of a distinct mRNA and the abundance of the corresponding protein might be low. This is the case for instance during oocyte maturation, shortly before the GVBD when t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5be55f88f736c0ae21c6f8c8315afdb
https://doi.org/10.1016/j.anireprosci.2012.08.005
https://doi.org/10.1016/j.anireprosci.2012.08.005
Publikováno v:
Molecular Reproduction and Development. 78:895-905
SUMMARY The implantation of the blastocyst into the endometrium is an indispensable premise for successful embryonic development. This process is regulated by maternal and embryonic signals that influence gene expression at the translational level, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d612b391539035732812e3fee0de6558
https://doi.org/10.1002/mrd.21376
https://doi.org/10.1002/mrd.21376
Publikováno v:
Toxicology Letters. 186:139-145
Mycotoxins as contaminants of animal food can impair fertility in farm animals. In the regulation of female fertility the ovarian steroid hormone progesterone (P(4)) plays an important role. In the present study we have investigated the influence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24286000f3f7ce8a7c5dc9c6ee635dd1
https://doi.org/10.1016/j.toxlet.2009.01.014
https://doi.org/10.1016/j.toxlet.2009.01.014
Autor:
Lucie Jelínková, Andrej Susor, Hana Kovarova, Pavla Karabinova, Helmut Torner, Wolfgang Tomek, Michal Kubelka
Publikováno v:
Molecular Reproduction and Development. 75:1716-1725
The binding of mRNAs to ribosomes is mediated by the protein complex eIF4F in conjunction with eIF4B (eukaryotic initiation factor 4F and 4B). EIF4F is a three subunit complex consisting of eIF4A (RNA helicase), eIF4E (mRNA cap binding protein), and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d2569eadc83cc4c73fcb72705b4445
https://doi.org/10.1002/mrd.20913
https://doi.org/10.1002/mrd.20913
Publikováno v:
Reproductive Toxicology. 24:317-325
Since a discrepancy concerning the effects of phytoestrogens on steroidogenesis exists in the literature we investigated the effects of genistein and daidzein on progesterone and estradiol synthesis in cultured primary granulosa cells derived from fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3029925145f47c89db572b427ddf0310
https://doi.org/10.1016/j.reprotox.2007.07.008
https://doi.org/10.1016/j.reprotox.2007.07.008
Publikováno v:
Reproduction in Domestic Animals. 42:167-175
In the pig, conceptus-derived oestrogens (days 11 and 12 of pregnancy) seem to be a critical component of the signalling mechanism for maternal recognition of pregnancy. Embryonic oestrogens can mediate effects on endometrial function by interactions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca45a21f0b5d3d64c13bccf255bff3a
https://doi.org/10.1111/j.1439-0531.2006.00747.x
https://doi.org/10.1111/j.1439-0531.2006.00747.x