Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Wolfgang, Miesbach"'
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/529ab5f01a02496ab0e3b693f67f2d2a
Autor:
Christian Herbert Burgmann, Ulrich J. Sachs, Karolin Trautmann-Grill, Christian Pfrepper, Paul Knöbl, Richard Greil, Johannes Oldenburg, Wolfgang Miesbach, Katharina Holstein, Hermann Eichler, Patrick Möhnle, Matthias Höpting, Christiane Dobbelstein, Robert Klamroth, Andreas Tiede
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102565- (2024)
Background: Persons with acquired hemophilia A are often older and suffer from comorbidity or frailty. Little is known about the impact on clinically relevant outcomes of acquired hemophilia A. Objectives: To assess the relevance of age, physical per
Externí odkaz:
https://doaj.org/article/f7f877abe5424c50a5a1fb6bb6878e21
Autor:
Wolfgang Miesbach, Greta Mulders, Daan Breederveld, Karen Pinachyan, Sandra Le Quellec, Ingrid Pabinger
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-10 (2024)
Abstract Background Adeno-associated virus (AAV)-based gene therapy for haemophilia has advanced substantially in the last 13 years; recently, three products have received approvals from regulatory authorities. Although the impact on quality of life
Externí odkaz:
https://doaj.org/article/8ffb5b42aa32428096d4d247c35af0e4
Autor:
Wolfgang Miesbach, Nicola Curry, Paul Knöbl, Charles Percy, Rita Santoro, Alvin H. Schmaier, Karolin Trautmann-Grill, Kayode Badejo, Jie Chen, Masoud Nouri, Pooja Oberai, Robert Klamroth
Publikováno v:
Therapeutic Advances in Hematology, Vol 15 (2024)
Background: Recombinant porcine factor VIII (rpFVIII; susoctocog alfa) is indicated for the treatment of bleeding events (BEs) in adults with acquired hemophilia A (AHA). Objectives: To assess the safety, utilization, and effectiveness of rpFVIII in
Externí odkaz:
https://doaj.org/article/7ebdeaa993c245398c87a2577b467f46
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Three major directions for the global progress of adeno-associated virus (AAV) vectors for gene therapies (GT) are analyzed: a) engineering vectors to increase transgene expression; b) aligning interests of the health system with costs and challenges
Externí odkaz:
https://doaj.org/article/b0dae454e1224619ab3bd48a8e7147d5
Autor:
Jan Hendrik Schaefer, Franziska Lieschke, Hans Urban, Ferdinand O. Bohmann, Florian Gatzke, Wolfgang Miesbach
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundThe clinical course of ischemic and hemorrhagic strokes can be influenced by the coagulation status of individual patients. The prior use of antiplatelet therapy (APT) such as acetylsalicylic acid (ASA) or P2Y12-antagonists has been inconsi
Externí odkaz:
https://doaj.org/article/b90de37635004835ba00a72a2665cdbd
Autor:
Rosa Sonja Alesci, Georg Goldmann, Susan Halimeh, Katharina Holstein, Christoph Königs, Wolfgang Miesbach, Christian Pfrepper, Martin Olivieri
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
IntroductionThe disease burden and bleeding risk of patients with mild hemophilia may be underestimated. Their health-related quality of life (QoL) may be negatively impacted by insufficient treatment and bleed-related joint damage connected to a pot
Externí odkaz:
https://doaj.org/article/19f8d462bcaa46e585eedb6913bcf9bd
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionInherited or acquired molecular abnormalities form a clinically heterogeneous group of fibrinogen disorders called dysfibrinogenaemia. Apart from a pediatric case report and in contrast to other clinical conditions, acquired dysfibrinogen
Externí odkaz:
https://doaj.org/article/f7d20694925e4d3e916a81cd47b84375
Autor:
Mark T. Reding, Ingrid Pabinger, Pål Andrè Holme, Monika Maas Enriquez, Maria Elisa Mancuso, Shadan Lalezari, Wolfgang Miesbach, Giovanni Di Minno, Robert Klamroth, Cedric Hermans
Publikováno v:
Therapeutic Advances in Hematology, Vol 14 (2023)
Background: Advances in treatment have enabled patients with haemophilia A to live longer and therefore may be subjected to comorbidities associated with ageing, in addition to disease-associated morbidities. There have been few reports to date on ef
Externí odkaz:
https://doaj.org/article/3106ae96a0814ef99d906c776d898f7c
Autor:
Miriam Anna Simon MD, Christina Klaeffling MD, Josephine Ward MD, Steffen Rauchfuss PhD, Wolfgang Miesbach MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 29 (2023)
Deep vein thrombosis (DVT) and the associated possible complication of pulmonary artery embolism (LAE) represent a recognized reason for significant perioperative morbidity and mortality. There is a risk of pulmonary artery embolism through embolizat
Externí odkaz:
https://doaj.org/article/18f40ec3f14d4f25ba9195ffcce523e0