Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Wolfgang, Meyerhof"'
Autor:
Eleni Roussa, Pavel Juda, Michael Laue, Oliver Mai-Kolerus, Wolfgang Meyerhof, Markus Sjöblom, Katerina Nikolovska, Ursula Seidler, Manfred W. Kilimann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Mutations in LRBA, a BEACH domain protein, cause severe immune deficiency in humans. LRBA is expressed in many tissues and organs according to biochemical analysis, but little is known about its cellular and subcellular localization, and its
Externí odkaz:
https://doaj.org/article/ae20a302c35e4f3284854560398bc7f7
Publikováno v:
Nutrients, Vol 16, Iss 9, p 1357 (2024)
Bitterness from phenylthiocarbamide and 6-n-propylthiouracil (PROP) varies with polymorphisms in the TAS2R38 gene. Three SNPs form two common (AVI, PAV) and four rare haplotypes (AAI, AAV, PVI, and PAI). AVI homozygotes exhibit higher detection thres
Externí odkaz:
https://doaj.org/article/9add61574f43430781e58323d74e9ef3
Autor:
Bernard P. Kok, Andrea Galmozzi, Nicole K. Littlejohn, Verena Albert, Cristina Godio, Woojoo Kim, Sean M. Kim, Jeffrey S. Bland, Neile Grayson, Mingliang Fang, Wolfgang Meyerhof, Gary Siuzdak, Supriya Srinivasan, Maik Behrens, Enrique Saez
Publikováno v:
Molecular Metabolism, Vol 16, Iss , Pp 76-87 (2018)
Objectives: Extracts of the hops plant have been shown to reduce weight and insulin resistance in rodents and humans, but elucidation of the mechanisms responsible for these benefits has been hindered by the use of heterogeneous hops-derived mixtures
Externí odkaz:
https://doaj.org/article/13cb3da1ba1b47f5b449b4d9690f02b2
Publikováno v:
Molecular Metabolism, Vol 6, Iss 11, Pp 1480-1492 (2017)
Objective: Hypothalamic tanycytes are glial cells that line the wall of the third ventricle and contact the cerebrospinal fluid (CSF). While they are known to detect glucose in the CSF we now show that tanycytes also detect amino acids, important nut
Externí odkaz:
https://doaj.org/article/db87f5cd7af6444a8d60de6ae51ad807
Autor:
Antonella Di Pizio, Louisa-Marie Kruetzfeldt, Shira Cheled-Shoval, Wolfgang Meyerhof, Maik Behrens, Masha Y. Niv
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Bitter taste is one of the basic taste modalities, warning against consuming potential poisons. Bitter compounds activate members of the bitter taste receptor (Tas2r) subfamily of G protein-coupled receptors (GPCRs). The number of functional
Externí odkaz:
https://doaj.org/article/f2c51f37776d4a93b2eea86820a84d7a
Autor:
Hans-Jürgen Wester, Annamaria Vezzani, Giovanni Tulipano, John E. Taylor, Stefan Schulz, Agnes Schonbrunn, Herbert Schmid, Marcus Schindler, Jean-Claude Reubi, Terry Reisine, Yogesh C. Patel, Anne-Marie O'Carroll, Wolfgang Meyerhof, Shlomo Melmed, Amelie Lupp, Hans-Jürgen Kreienkamp, Patrick P. A. Humphrey, Daniel Hoyer, Leo Hofland, Rebecca Hills, Anthony Harmar, Wasyl Feniuk, Jacques Epelbaum, Pascal Dournaud, Micheal Culler, Zsolt Csaba, Justo P. Castaño, Corinne Bosquet
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
Somatostatin (somatotropin release inhibiting factor) is an abundant neuropeptide, which acts on five subtypes of somatostatin receptor (SST1-SST5; nomenclature as agreed by the NC-IUPHAR Subcommittee on Somatostatin Receptors [98]). Activation of th
Publikováno v:
Nutrients, Vol 12, Iss 4, p 995 (2020)
Renal excretion and sodium appetite provide the basis for sodium homeostasis. In both the kidney and tongue, the epithelial sodium channel (ENaC) is involved in sodium uptake and sensing. The diuretic drug amiloride is known to block ENaC, producing
Externí odkaz:
https://doaj.org/article/14ca552231234e1fbb2261bd4ff129b0
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The Embden–Meyerhof–Parnas (EMP) pathway comprises eleven cytosolic enzymes interacting to metabolize glucose to lactic acid [CH3CH(OH)COOH]. Glycolysis is largely considered as the conversion of glucose to pyruvate (CH3COCOO-). We consider glyco
Externí odkaz:
https://doaj.org/article/0e47f6d90bf2454f9cc4c9ce9ee24d43
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Chickens sense the bitter taste of structurally different molecules with merely three bitter taste receptors (Gallus gallus taste 2 receptors, ggTas2rs), representing a minimal case of bitter perception. Some bitter compounds like quinine, diphenidol
Externí odkaz:
https://doaj.org/article/8d0cdc5ca93c4a0780ee8073059f9037
Autor:
Thomas Hofmann, Wolfgang Meyerhof, Timo Babinger, Christian Schmid, Stephen Pickrahn, Corinna Dawid, Anne Brockhoff
Publikováno v:
Journal of Agricultural and Food Chemistry. 69:5510-5527
We report on activity-guided investigation of the key antisweet principles of Gymnema sylvestre. Orosensory-guided fractionation by means of solid phase extraction, preparative 2D-LC, and semipreparative HPLC followed by accurate MS and 1D/2D NMR exp