Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Wolfgang, Hammerschmidt"'
Autor:
Sebastian J. Theobald, Elena Fiestas, Andreas Schneider, Benjamin Ostermann, Simon Danisch, Constantin von Kaisenberg, Jan Rybniker, Wolfgang Hammerschmidt, Reinhard Zeidler, Renata Stripecke
Publikováno v:
Cells, Vol 13, Iss 1, p 20 (2023)
Antiviral neutralizing antibodies (nAbs) are commonly derived from B cells developed in immunized or infected animals and humans. Fully human antibodies are preferred for clinical use as they are potentially less immunogenic. However, the function of
Externí odkaz:
https://doaj.org/article/fbf2eb71ec7849e58367a95268336eee
Autor:
Johannes Roessler, Dagmar Pich, Verena Krähling, Stephan Becker, Oliver T. Keppler, Reinhard Zeidler, Wolfgang Hammerschmidt
Publikováno v:
Biomedicines, Vol 11, Iss 11, p 2892 (2023)
The successful development of effective viral vaccines depends on well-known correlates of protection, high immunogenicity, acceptable safety criteria, low reactogenicity, and well-designed immune monitoring and serology. Virus-neutralizing antibodie
Externí odkaz:
https://doaj.org/article/ed0cf5c608c74d6ea76230c07a70e471
Autor:
Julius Nückel, Elisa Planatscher, Anne Wiebe Mohr, Karolin Deichl, Hrvoje Mijočević, Martin Feuerherd, Lisa Wolff, Johanna Erber, Jochen Schneider, Michael Quante, Christoph Winter, Jürgen Ruland, Alexander Hapfelmeier, Wolfgang Hammerschmidt, Andreas Moosmann, Ulrike Protzer, Uta Behrends, Josef Mautner
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Understanding immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is crucial to contain the COVID-19 pandemic. Using a multiplex approach, serum IgG responses against the whole SARS-CoV-2 proteome and the nucleocapsid pro
Externí odkaz:
https://doaj.org/article/fe87ee6f674d43778acc467d3a27c4c1
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Epstein-Barr virus (EBV) is a double-stranded DNA virus of the Herpesviridae family. This virus preferentially infects human primary B cells and persists in the human B cell compartment for a lifetime. Latent EBV infection can lead to the development
Externí odkaz:
https://doaj.org/article/d8f5709fa96e4a40b4a75908642ea39f
Autor:
Constanze Slabik, Maja Kalbarczyk, Simon Danisch, Reinhard Zeidler, Frank Klawonn, Valery Volk, Nicole Krönke, Friedrich Feuerhake, Constanca Ferreira de Figueiredo, Rainer Blasczyk, Henning Olbrich, Sebastian J. Theobald, Andreas Schneider, Arnold Ganser, Constantin von Kaisenberg, Stefan Lienenklaus, Andre Bleich, Wolfgang Hammerschmidt, Renata Stripecke
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 504-524 (2020)
Epstein-Barr virus (EBV) is a latent and oncogenic human herpesvirus. Lytic viral protein expression plays an important role in EBV-associated malignancies. The EBV envelope glycoprotein 350 (gp350) is expressed abundantly during EBV lytic reactivati
Externí odkaz:
https://doaj.org/article/2fc8de586f414bb99c562beadaeda7fb
Autor:
Wen-Hsin Liu, Paulina Mrozek-Gorska, Anna-Katharina Wirth, Tobias Herold, Larissa Schwarzkopf, Dagmar Pich, Kerstin Völse, M. Camila Melo-Narváez, Michela Carlet, Wolfgang Hammerschmidt, Irmela Jeremias
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background Clinically relevant methods are not available that prioritize and validate potential therapeutic targets for individual tumors, from the vast amount of tumor descriptive expression data. Methods We established inducible transgene
Externí odkaz:
https://doaj.org/article/959c31577ec848568d189cab46db5c31
Autor:
Narendran Reguraman, Asma Hassani, Pretty S. Philip, Dagmar Pich, Wolfgang Hammerschmidt, Gulfaraz Khan
Publikováno v:
Vaccines, Vol 11, Iss 3, p 540 (2023)
Epstein–Barr virus (EBV) is etiologically associated with a number of malignant and non-malignant conditions. Thus, a prophylactic vaccine against this virus could help to reduce the burden of many EBV-associated diseases. Previously, we reported t
Externí odkaz:
https://doaj.org/article/21ac2aba6b2d41998467eb93e936990e
Autor:
Danielle Westhoff Smith, Adityarup Chakravorty, Mitch Hayes, Wolfgang Hammerschmidt, Bill Sugden
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT The innate immune system serves as frontline defense against pathogens, such as bacteria and viruses. Natural killer (NK) cells are a part of innate immunity and can both secrete cytokines and directly target cells for lysis. NK cells expres
Externí odkaz:
https://doaj.org/article/fcb5c04ba91646ffb3394fca6fb5d9f7
Autor:
Manuel Albanese, Yen-Fu Adam Chen, Corinna Hüls, Kathrin Gärtner, Takanobu Tagawa, Ernesto Mejias-Perez, Oliver T Keppler, Christine Göbel, Reinhard Zeidler, Mikhail Shein, Anne K Schütz, Wolfgang Hammerschmidt
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009951 (2021)
Mammalian cells release different types of vesicles, collectively termed extracellular vesicles (EVs). EVs contain cellular microRNAs (miRNAs) with an apparent potential to deliver their miRNA cargo to recipient cells to affect the stability of indiv
Externí odkaz:
https://doaj.org/article/877eaf79497e4c6682baf88c077b9f50
Autor:
Ezgi Akidil, Manuel Albanese, Alexander Buschle, Adrian Ruhle, Dagmar Pich, Oliver T Keppler, Wolfgang Hammerschmidt
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009117 (2021)
Gene editing is now routine in all prokaryotic and metazoan cells but has not received much attention in immune cells when the CRISPR-Cas9 technology was introduced in the field of mammalian cell biology less than ten years ago. This versatile techno
Externí odkaz:
https://doaj.org/article/a532f190d5ea453cb33f6fc4c2b5bc26