Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Wolf-Dieter Lienhart"'
Autor:
Emilia, Strandback, Wolf-Dieter, Lienhart, Altijana, Hromic-Jahjefendic, Benjamin, Bourgeois, Anja, Högler, Daniel, Waltenstorfer, Andreas, Winkler, Klaus, Zangger, Tobias, Madl, Karl, Gruber, Peter, Macheroux
Publikováno v:
Febs Letters
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a human FAD‐dependent enzyme that plays a crucial role in the antioxidant defense system. A naturally occurring single‐nucleotide polymorphism (NQO1*2) in the NQO1 gene leads to an amino acid substitutio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a0005d31f0a1f5021f7ecf8866ca352
https://pubmed.ncbi.nlm.nih.gov/31605637
https://pubmed.ncbi.nlm.nih.gov/31605637
Autor:
Maximilian Aigner, Astrid Ortner, S.R. Wallner, Dale E. Edmondson, Peter Macheroux, Kurt Kalcher, Wolf-Dieter Lienhart
Publikováno v:
Electroanalysis. 29:367-373
A specific and sensitive electrochemical biosensor with human monoamine oxidase B (hMAO B) as biological receptor and a MnO2 modified nanomaterial based transducer system has been developed and optimised. Best results for the biosensor were achieved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d41c876944adcb49a4f81ddf89857d07
https://doi.org/10.1002/elan.201600326
https://doi.org/10.1002/elan.201600326
Autor:
Verena Resch, Simon C. Willies, Bas Groenendaal, Barbara Grischek, Johann H. Sattler, Joerg H. Schrittwieser, Diego Ghislieri, Ian Rowles, Wolf-Dieter Lienhart, Nicholas J. Turner, Wolfgang Kroutil, Eva-Maria Fischereder
Publikováno v:
Catal. Sci. Technol.. 4:3657-3664
Chemo-enzymatic deracemisation was applied to obtain the (S)-enantiomer of 1-benzylisoquinolines from the racemate in high isolated yield (up to 85%) and excellent optical purity (ee > 97%). The one-pot deracemisation protocol encompassed enantiosele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8c166c256f956cd7de35eaac48988db
https://doi.org/10.1039/c4cy00642a
https://doi.org/10.1039/c4cy00642a
Autor:
Wolf-Dieter, Lienhart, Emilia, Strandback, Venugopal, Gudipati, Karin, Koch, Alexandra, Binter, Michael K, Uhl, David M, Rantasa, Benjamin, Bourgeois, Tobias, Madl, Klaus, Zangger, Karl, Gruber, Peter, Macheroux
Publikováno v:
The FEBS journal
The human NAD(P)H:quinone oxidoreductase 1 (NQO1; EC 1.6.99.2) is an essential enzyme in the antioxidant defence system. Furthermore, NQO1 protects tumour suppressors like p53, p33ING1b and p73 from proteasomal degradation. The activity of NQO1 is al
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3840177ca00e847092040aeff823d433
https://pubmed.ncbi.nlm.nih.gov/28236663
https://pubmed.ncbi.nlm.nih.gov/28236663
Autor:
Wolf-Dieter Lienhart, Silvia Wallner, Verena Resch, Wolfgang Kroutil, Johann H. Sattler, Peter Macheroux, Joerg H. Schrittwieser, Jasmin Resch
Publikováno v:
The Journal of Organic Chemistry
A chemoenzymatic approach for the asymmetric total synthesis of the title compounds is described that employs an enantioselective oxidative C-C bond formation catalyzed by berberine bridge enzyme (BBE) in the asymmetric key step. This unique reaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49208a8d0ec484280f7a2ad3e9ac582d
https://doi.org/10.1021/jo201056f
https://doi.org/10.1021/jo201056f
Autor:
Verena Resch, Peter Macheroux, Johann H. Sattler, Katharina Durchschein, Joerg H. Schrittwieser, Karl Gruber, Wolf-Dieter Lienhart, Andreas Winkler, Wolfgang Kroutil
Publikováno v:
Angewandte Chemie. 123:1100-1103
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c123b1cbd83a6e9aac3dee4c1c38721
https://doi.org/10.1002/ange.201006268
https://doi.org/10.1002/ange.201006268
Autor:
Wolf-Dieter, Lienhart, Venugopal, Gudipati, Michael K, Uhl, Alexandra, Binter, Sergio A, Pulido, Robert, Saf, Klaus, Zangger, Karl, Gruber, Peter, Macheroux
Publikováno v:
The FEBS journal
Humanquinone oxidoreductase 1 (NQO1) is essential for the antioxidant defense system, stabilization of tumor suppressors (e.g. p53, p33, and p73), and activation of quinone-based chemotherapeutics. Overexpression of NQO1 in many solid tumors, coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd7c0bcdc38a91cc8bbeb3ca1752573f
https://pubmed.ncbi.nlm.nih.gov/25143260
https://pubmed.ncbi.nlm.nih.gov/25143260
Publikováno v:
Biochimica et Biophysica Acta
Genome analysis of the yeast Saccharomyces cerevisiae identified 68 genes encoding flavin-dependent proteins (1.1% of protein encoding genes) to which 47 distinct biochemical functions were assigned. The majority of flavoproteins operate in mitochond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::039ac9c95b273761423db1a867c98826
https://pubmed.ncbi.nlm.nih.gov/24373875
https://pubmed.ncbi.nlm.nih.gov/24373875
Autor:
Verena Resch, Andreas Winkler, Peter Macheroux, Johann H. Sattler, Wolfgang Kroutil, Wolf-Dieter Lienhart, Joerg H. Schrittwieser, Karl Gruber, Katharina Durchschein
Publikováno v:
Angewandte Chemie (International ed. in English). 50(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937f273cc9b8694d696ada5182451ded
https://pubmed.ncbi.nlm.nih.gov/21268196
https://pubmed.ncbi.nlm.nih.gov/21268196
Autor:
Andreas Winkler, Wolfgang Kroutil, Verena Resch, Wolf-Dieter Lienhart, Peter Macheroux, Johann H. Sattler, Joerg H. Schrittwieser, Karl Gruber, Katharina Durchschein
Publikováno v:
Angewandte Chemie. 123:999-999
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038412ac9e35bd1b6c11260d0402449d
https://doi.org/10.1002/ange.201007479
https://doi.org/10.1002/ange.201007479