Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Wolf P. Hofmann"'
Autor:
Johannes Lübke, Nicole Naumann, Oliver Hoffmann, Hans-Peter Horny, Karl Sotlar, Martina Rudelius, Georgia Metzgeroth, Alice Fabarius, Wolf-Karsten Hofmann, Andreas Reiter, Juliana Schwaab
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In 70 patients with KIT D816V positive systemic mastocytosis (SM) including 36 patients with advanced SM (AdvSM), we correlated the extent of reported mucosal mast cell ([m]MC) infiltration of the upper and/or lower gastrointestinal tract (U
Externí odkaz:
https://doaj.org/article/401bed6d276b43f0807e3552a3d9913f
Autor:
Hanna Hirschinger, Evelyn Jaeger, Stefanie Nittka, Svetlana Hetjens, Christine Lorenz, Constanze Remi, Susanne Saussele, Wolf-K. Hofmann, Deniz Gencer, Tobias Boch
Publikováno v:
BMC Palliative Care, Vol 23, Iss 1, Pp 1-7 (2024)
Abstract Background Intranasal (i.n.) drug application is a widely known and low-invasive route of administration that may be able to achieve rapid symptom control in terminally ill patients. According to the German S3 guideline “Palliative care fo
Externí odkaz:
https://doaj.org/article/3ac82afd2aeb4788b503d915f9d4402b
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Myelodysplastic neoplasms (MDS) are a heterogenous group of clonal stem cell disorders characterized by dysplasia and cytopenia in one or more cell lineages. Anemia is a very common symptom that is often treated with blood transfusions and/or erythro
Externí odkaz:
https://doaj.org/article/831c8603311d446a8091d0cdad71b2c6
Autor:
Eva Altrock, Carla Sens-Albert, Franziska Hofmann, Vladimir Riabov, Nanni Schmitt, Qingyu Xu, Johann-Christoph Jann, Felicitas Rapp, Laurenz Steiner, Alexander Streuer, Verena Nowak, Julia Obländer, Nadine Weimer, Iris Palme, Melda Göl, Ali Darwich, Patrick Wuchter, Georgia Metzgeroth, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Robust and reliable in vitro and in vivo models of primary cells are necessary to study the pathomechanisms of Myelodysplastic Neoplasms (MDS) and identify novel therapeutic strategies. MDS-derived hematopoietic stem and progenito
Externí odkaz:
https://doaj.org/article/3d993a6d3dfe43489fb55296d3d2a803
Autor:
Qingyu Xu, Alexander Streuer, Johann-Christoph Jann, Eva Altrock, Nanni Schmitt, Johanna Flach, Carla Sens-Albert, Felicitas Rapp, Julia Wolf, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Mariia Kuzina, Ahmed Jawhar, Ali Darwich, Cleo-Aron Weis, Alexander Marx, Patrick Wuchter, Victor Costina, Evelyn Jäger, Elena Sperk, Michael Neumaier, Alice Fabarius, Georgia Metzgeroth, Florian Nolte, Laurenz Steiner, Pavel A. Levkin, Mohamad Jawhar, Wolf-Karsten Hofmann, Vladimir Riabov, Daniel Nowak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Hypomethylating agents, such as 5-Azacytidine (5-AZA), are standard of care for patients with myelodysplastic and myeloid malignancies, however response rates are limited and risk of relapses high. Here the authors show that inhibition of lysyl oxida
Externí odkaz:
https://doaj.org/article/91b523f59ac547d99572fb13b46e1d2f
Autor:
Vladimir Riabov, Qingyu Xu, Nanni Schmitt, Alexander Streuer, Guo Ge, Lyndsey Bolanos, Mark Wunderlich, Johann-Christoph Jann, Alina Wein, Eva Altrock, Marie Demmerle, Sanjay Mukherjee, Abdullah Mahmood Ali, Felicitas Rapp, Verena Nowak, Nadine Weimer, Julia Obländer, Iris Palme, Melda Göl, Ahmed Jawhar, Ali Darwich, Patrick Wuchter, Christel Weiss, Azra Raza, Jason M. Foulks, Daniel T. Starczynowski, Feng-Chun Yang, Georgia Metzgeroth, Laurenz Steiner, Mohamad Jawhar, Wolf-Karsten Hofmann, Daniel Nowak
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Inhibitors of anti-apoptotic BCL-2 family proteins in combination with chemotherapy and hypomethylating agents (HMA) are promising therapeutic approaches in acute myeloid leukemia (AML) and high-risk myelodysplastic syndromes (MDS). Alvocidib, a cycl
Externí odkaz:
https://doaj.org/article/587fe7bf73e84c44b2b804ab4433a656
Autor:
Nicole Naumann, Ulrike Bross‐Bach, Wolfgang Seifarth, Alice Fabarius, Wolf‐Karsten Hofmann, Susanne Saußele, Birgit Spiess
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1339-1342 (2022)
Abstract Quantitative reverse transcription polymerase chain reaction (qRT‐PCR) of BCR‐ABL1 transcript level is an essential part of routine disease monitoring in patients with chronic myeloid leukemia. One patient sample (e13a2 transcript detect
Externí odkaz:
https://doaj.org/article/b3ffd407b32e46d39100c0feee65d6d9
Autor:
Markus Pfirrmann, Francois-Xavier Mahon, Stéphanie Dulucq, Andreas Hochhaus, Panayiotis Panayiotidis, Antonio Almeida, Jiri Mayer, Henrik Hjorth-Hansen, Jeroen J. W. M. Janssen, Satu Mustjoki, Joaquín Martinez-Lopez, Hanne Vestergaard, Hans Ehrencrona, Veli Kairisto, Kateřina Machová Poláková, Franck Emmanuel Nicolini, Wolf-Karsten Hofmann, Joëlle Guilhot, Susanne Saussele, Johan Richter
Publikováno v:
HemaSphere, Vol 7, p e230884b (2023)
Externí odkaz:
https://doaj.org/article/f21cdde0c6114e2fb555ae09f10c9dbe
Autor:
Elena Crisà, María Díez Campelo, Ulrich Germing, Elvira Mora Castera, Francisca Hernandez Mohedo, Kündgen Andrea, Ebeling Freja, Mikko Myllymäki, Martin Jädersten, Eva Hellström Lindberg, Detlef Haase, Isabella Capodanno, Antonella Poloni, Carlo Finelli, Monica Crugnola, Claudio Fozza, Anna Calvisi, Chiara Frairia, Giuseppe Pietrantuono, Marco Cerrano, Rosanna Ciancia, Daniela Barraco, Wolf-Karsten Hofmann, Axel Ruefer, Cécile Bally, Pierre Fenaux, Guillermo Sanz Santillana, Valeria Santini
Publikováno v:
HemaSphere, Vol 7, p e93218cc (2023)
Externí odkaz:
https://doaj.org/article/5d4df74826ee436192fd2b3c2563413d
Autor:
Johannes Lübke, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, Timo Brand, Hans-Peter Horny, Karl Sotlar, Wolf-Karsten Hofmann, Juliana Schwaab, Andreas Reiter
Publikováno v:
HemaSphere, Vol 7, p e472819b (2023)
Externí odkaz:
https://doaj.org/article/340457ea6c1f4b7cbd4ba14f78640ecd