Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wolf Oehrl"'
Publikováno v:
Cellular Signalling. 25:429-438
Mitogen-activated protein kinase (MAPK) cascades are involved in the regulation of cellular proliferation, differentiation, survival, apoptosis, as well as in inflammatory responses. Signal intensity and duration have been recognized as crucial param
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945124efc78c9cb6197baea70f67ae2e
https://doi.org/10.1016/j.cellsig.2012.11.010
https://doi.org/10.1016/j.cellsig.2012.11.010
Publikováno v:
Cellular Signalling. 24:664-676
Specific outcomes upon activation of the c-Jun N-terminal kinase (JNK) pathway critically depend on the intensity and duration of signal transmission. Dual-specificity phosphatases (DUSPs) play a very important role in these events by modulating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc59264d7ceb7110ed125972eb2bfbc
https://doi.org/10.1016/j.cellsig.2011.10.015
https://doi.org/10.1016/j.cellsig.2011.10.015
Publikováno v:
Journal of Biological Chemistry. 278:17819-17826
Numerous extracellular agonists induce consecutive stimulation of Ras guanine nucleotide exchange factors, Ras and c-Raf1, as the starting point of the intracellular mitogen-activated protein kinase cascade. Recent data point to a more complex reacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85df2a33e51af9f2368608249c083ab
https://doi.org/10.1074/jbc.m209951200
https://doi.org/10.1074/jbc.m209951200
Autor:
Solveig Hehl, Reinhard Wetzker, Borislav Stoyanov, Roland Schönherr, Wolf Oehrl, Stefan H. Heinemann
Publikováno v:
Biochemical Journal. 360:691-698
Type-I phosphoinositide 3-kinases (PI3Ks) were characterized as a group of intracellular signalling proteins expressing both protein and lipid kinase activities. Recent studies implicate PI3Ks as mediators of oocyte maturation, but the molecular mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::defdfe40231fd32ff2d212b415e8fa02
https://doi.org/10.1042/bj3600691
https://doi.org/10.1042/bj3600691
Autor:
Pin Ling, Zhengbin Yao, Christian Meyer, Wolf Oehrl, Stephan M. Feller, Tse-Hua Tan, Xuhong Sunny Wang
Publikováno v:
Molecular and Cellular Biology. 19:1359-1368
Hematopoietic progenitor kinase 1 (HPK1), a mammalian Ste20-related protein kinase, is an upstream activator of c-Jun N-terminal kinase (JNK). In order to further characterize the HPK1-mediated JNK signaling cascade, we searched for HPK1-interacting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca82eb74a4a0874b281b6e7a60d32d6
https://doi.org/10.1128/mcb.19.2.1359
https://doi.org/10.1128/mcb.19.2.1359
Autor:
Diane Schaak, Randall E. Burton, Wolf Oehrl, Terry L. Boose, Scott R. Horner, Jacquelyn S. Fetrow
Publikováno v:
Protein Science. 6:197-210
Omega (omega)-loop A, residues 18-32 in wild-type yeast iso-1-cytochrome c, has been deleted and replaced with loop sequences from three other cytochromes c and one from esterase. Yeast expressing a partial loop deletion do not contain perceptible am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b6ad854392815c94588e8412f1bb08
https://doi.org/10.1002/pro.5560060122
https://doi.org/10.1002/pro.5560060122
Autor:
George Panayotou, Wolf Oehrl
Publikováno v:
Connective tissue research. 49(3)
Growth factors were historically defined as molecules produced by the body to regulate cell growth and proliferation. After the identification of their receptors and the intracellular signaling machinery they activate, it is now clear that they are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e714eca90c3fde1398dab80b8ef6da3
https://pubmed.ncbi.nlm.nih.gov/18661330
https://pubmed.ncbi.nlm.nih.gov/18661330
Publikováno v:
Free radical research. 37(6)
Apoptosis is an active form of cell death that is initiated by a variety of stimuli, including reactive oxygen species (ROS) and ultraviolet (UV) radiation. Previously, it has been reported that UVB-irradiation of keratinocytes leads to intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd87f27400f499d86cdb7b5af8a80a9
https://pubmed.ncbi.nlm.nih.gov/12868492
https://pubmed.ncbi.nlm.nih.gov/12868492
Autor:
Wolf Oehrl, Marijana Petković, Jürgen Arnhold, Regina Heinze, Reinhard Wetzker, Matthias M. Müller, Klaus Arnold, Jürgen Schiller
Publikováno v:
Chemistry and physics of lipids. 110(2)
Matrix-assisted laser desorption and ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been recently established as a powerful tool for the analysis of biomolecules. Here, MALDI-TOF MS was used for the detection of (poly-)phosphoinositid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56fac1bb155e4bdbdaddc6ac86d35085
https://pubmed.ncbi.nlm.nih.gov/11369324
https://pubmed.ncbi.nlm.nih.gov/11369324
Autor:
Gen-Sheng Feng, Christian Kardinal, Tse-Hua Tan, Sandra Ruf, Stephan M. Feller, John Blenis, Knut Adermann, John Groffen, Wolf Oehrl
Publikováno v:
Oncogene. 17(15)
Adapter proteins function by mediating the rapid and specific assembly of multi-protein complexes during the signal transduction which guards proliferation, differentiation and many functions of higher eukaryotic cells. To understand their functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f4774a296b5a27c30df7b4f93c4d82
https://pubmed.ncbi.nlm.nih.gov/9788432
https://pubmed.ncbi.nlm.nih.gov/9788432