OCT4 Expression in Outgrowth Colonies Derived from Porcine Inner Cell Masses and Epiblasts

Autor: Wolf, XA, Rasmussen, MA, Schauser, K, Jensen, AT, Schmidt, M, Hyttel, P

Publikováno v: Reproduction in Domestic Animals; Vol 46

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=ec_fp7health::b4375300a81957aa0d1c8789c4ba58a5

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The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.

Autor: Tsonkova VG; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark; University of Copenhagen, Department of Biomedical Sciences, Blegdamsvej 3B, DK-2200, Copenhagen, Denmark., Sand FW; Novo Nordisk A/S, Diabetes Research, GLP-1 & T2D Pharmacology, Novo Nordisk Park, 2760, Maaloev, Denmark., Wolf XA; Novo Nordisk A/S, Diabetes Research, GLP-1 & T2D Pharmacology, Novo Nordisk Park, 2760, Maaloev, Denmark., Grunnet LG; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Kirstine Ringgaard A; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark; University of Copenhagen, Department of Biomedical Sciences, Blegdamsvej 3B, DK-2200, Copenhagen, Denmark., Ingvorsen C; Novo Nordisk A/S, Diabetes Research, Histology & Imaging, Novo Nordisk Park, 2760, Maaloev, Denmark., Winkel L; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Kalisz M; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Dalgaard K; Novo Nordisk A/S, Diabetes Research, GLP-1 & T2D Pharmacology, Novo Nordisk Park, 2760, Maaloev, Denmark., Bruun C; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Fels JJ; Novo Nordisk A/S, Discovery Biology & Technology, Research Bioanalysis, Novo Nordisk Park, 2760, Maaloev, Denmark., Helgstrand C; Novo Nordisk A/S, Protein Engineering, Expression Technologies 1, Novo Nordisk Park, 2760, Maaloev, Denmark., Hastrup S; Novo Nordisk A/S, Protein Engineering, Expression Technologies 1, Novo Nordisk Park, 2760, Maaloev, Denmark., Öberg FK; Novo Nordisk A/S, Protein Engineering, Expression Technologies 1, Novo Nordisk Park, 2760, Maaloev, Denmark., Vernet E; Novo Nordisk Research Center Seattle Inc., Protein Engineering, NNRC Seattle, Inc., 530 Fairview Avenue North, 98109, Seattle, WA, USA., Sandrini MPB; Novo Nordisk A/S, Protein Engineering, Upstream Technologies, Novo Nordisk Park, 2760, Maaloev, Denmark., Shaw AC; Novo Nordisk A/S, Protein Engineering, Characterisation & Modelling Technology, Novo Nordisk Park, 2760, Maaloev, Denmark., Jessen C; Novo Nordisk A/S, Protein Engineering, Protein & Peptide Chemistry 2, Novo Nordisk Park, 2760, Maaloev, Denmark., Grønborg M; Novo Nordisk A/S, Discovery Biology & Technology, Discovery ADME, Novo Nordisk Park, 2760, Maaloev, Denmark., Hald J; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Willenbrock H; Novo Nordisk A/S, Discovery Biology & Technology, Bioinformatics, Maaloev, Denmark., Madsen D; Novo Nordisk A/S, Discovery Biology & Technology, Bioinformatics, Maaloev, Denmark., Wernersson R; Intomics A/S, Lottenborgvej 26, DK-2800, Lyngby, Denmark., Hansson L; Intomics A/S, Lottenborgvej 26, DK-2800, Lyngby, Denmark; Novo Nordisk Pharma Ltd., Research Centre Oxford, Bioinformatics, Novo Nordisk Ltd., 3 City Place Beehive Ring Road, Gatwick, RH6 0PA, West Sussex, United Kingdom., Jensen JN; Novo Nordisk Pharma Ltd., Research Centre Oxford, Bioinformatics, Novo Nordisk Ltd., 3 City Place Beehive Ring Road, Gatwick, RH6 0PA, West Sussex, United Kingdom., Plesner A; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Alanentalo T; Novo Nordisk A/S, Diabetes Research, Histology & Imaging, Novo Nordisk Park, 2760, Maaloev, Denmark., Petersen MBK; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark; University of Copenhagen, DanStem, Blegdamsvej 3B, DK-2200, Copenhagen, Denmark., Grapin-Botton A; University of Copenhagen, DanStem, Blegdamsvej 3B, DK-2200, Copenhagen, Denmark., Honoré C; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Ahnfelt-Rønne J; Novo Nordisk A/S, Diabetes Research, Histology & Imaging, Novo Nordisk Park, 2760, Maaloev, Denmark., Hecksher-Sørensen J; Novo Nordisk A/S, Diabetes Research, Histology & Imaging, Novo Nordisk Park, 2760, Maaloev, Denmark., Ravassard P; Institut du cerveau et de la moelle (ICM) - Hôpital Pitié-Salpêtrière, Boulevard de l'Hôpital, Sorbonne Universités, Inserm, CNRS, UPMC Univ, Paris 06, Paris, France., Madsen OD; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Rescan C; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark., Frogne T; Novo Nordisk A/S, Diabetes Research, Department of Islet & Stem Cell Biology, Novo Nordisk Park, 2760, Maaloev, Denmark. Electronic address: tfro@novonordisk.com.

Publikováno v: Molecular metabolism [Mol Metab] 2018 Feb; Vol. 8, pp. 144-157. Date of Electronic Publication: 2017 Dec 19.

Identification of a conserved cis-acting region driving expression of mouse Eomesodermin to the primitive streak, node, and definitive endoderm.

Autor: Wolf XA; Hagedorn Research Institute, Niels Steensensvej 6, DK-2820 Gentofte, Denmark. xea@hagedorn.dk, Klein T, Garcia R, Hyttel P, Serup P

Publikováno v: Gene expression patterns : GEP [Gene Expr Patterns] 2012 Jan-Feb; Vol. 12 (1-2), pp. 85-93. Date of Electronic Publication: 2011 Jul 08.