Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wojciech Wojtas-Niziurski"'
Publikováno v:
eLife, Vol 6 (2017)
Potassium channels are opened by ligands and/or membrane potential. In voltage-gated K+ channels and the prokaryotic KcsA channel, conduction is believed to result from opening of an intracellular constriction that prevents ion entry into the pore. O
Externí odkaz:
https://doaj.org/article/401d53a3f00a424abd5f848f51324858
Autor:
Simon Bernèche, Florian T Heer, Wojciech Wojtas-Niziurski, Crina M. Nimigean, David J. Posson
Publikováno v:
eLife, Vol 6 (2017)
Potassium channels are proteins found in almost all living organisms and are vital for many different biological processes. These proteins contain a pore that allows potassium ions to flow through cell membranes, but only when the channel is open. Mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c064a763ad41edeef5ca7db1658e88e
https://edoc.unibas.ch/56965/
https://edoc.unibas.ch/56965/
Publikováno v:
Journal of Chemical Theory and Computation
The potential of mean force describing conformational changes of biomolecules is a central quantity that determines the function of biomolecular systems. Calculating an energy landscape of a process that depends on three or more reaction coordinates
Publikováno v:
Biophysical Journal. 106:234a
Ion efflux through potassium channels is regulated by a main gate controlled by ligands and/or the transmembrane voltage. The opening of the main gate let K ions flow down their gradient, diffusing through the selectivity filter of the channel, which
Autor:
Wojciech Wojtas-Niziurski
Publikováno v:
Biophysical Journal. 100:610a
The potential of mean force (PMF) describing the conformational changes of biomolecules is a central quantity that determines the function of biomolecular systems. Calculating a multidimensional PMF (free energy landscape) is a time consuming process