Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wojciech Strozek"'
Autor:
Andrzej Skladanowski, Marek Wojciechowski, Krzysztof Lemke, Danuta Pirska, Marek T. Konieczny, Wojciech Strozek, Anita Buɬakowska, Michal Sabisz, Wojciech Konieczny, Anna Pieczykolan
Publikováno v:
European Journal of Medicinal Chemistry. 89:733-742
Synthesis, in vitro cytotoxic activity, and interaction with tubulin of (E)-1-(6-alkoxybenzo[d][1,3]oxathiol-5-yl)-3-phenylprop-2-en-1-one derivatives (2) are described. Some of the compounds demonstrated cytotoxic activity at submicromolar concentra
Autor:
Anna Pieczykolan, Katarzyna Bukato, Sebastian Pawlak, Katarzyna Poleszak, Maciej Masłyk, Albert Jaworski, Konrad Kubiński, Marlena Gałązka, Jerzy Pieczykolan, Wojciech Strozek, Piotr Rózga, Rafal Zielinski, Malgorzata Teska-Kaminska, Michal Szymanik, Bartłomiej Żerek, Robert Świder
Publikováno v:
Investigational new drugs. 32(6)
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptors became promising molecules for selective targeting of tumor cells without affecting normal tissue. Unfortunately, cancer cells have developed a number of mechanisms tha
Autor:
Marlena Galazka, Katarzyna Bukato, Sebastian Pawlak, Bartlomiej Zerek, Katarzyna Poleszak, Wojciech Strozek, Piotr Rózga, Malgorzata Teska-Kaminska, Anna Pieczykolan, Jerzy Pieczykolan, Albert Jaworski, Michal Szymanik
Publikováno v:
Cancer Research. 74:2773-2773
Background The tumor necrosis factor related apoptosis-inducing ligand (TRAIL/Apo2L) is a member of the TNF superfamily that initiates apoptosis of tumor cells through the activation of their death receptors. The ability of TRAIL to selectively induc
Autor:
Marlena Galazka, Piotr Rózga, Malgorzata Teska-Kaminska, Wojciech Strozek, Jerzy Pieczykolan, Katarzyna Bukato, Sebastian Pawlak, Michal Szymanik, Albert Jaworski, Katarzyna Poleszak, Bartlomiej Zerek, Anna Pieczykolan
Publikováno v:
Cancer Research. 74:4471-4471
Although standard chemotherapy is still one of the most effective treatment for many types of cancer - often causes side effects. Chemotherapeutic agents primarily damage cancer cells with a rapidly dividing and growing profile, thereby also destroy
Autor:
Katarzyna Poleszak, Jerzy Pieczykolan, Katarzyna Bukato, Anna Pieczykolan, Sebastian Pawlak, Wojciech Strozek, Michal Szymanik, Albert Jaworski, Piotr Rózga, Malgorzata Teska-Kaminska, Marlena Galaska, Bartlomiej Zerek
Publikováno v:
Cancer Research. 74:3796-3796
Background Cancer growth and development is tightly related to both new vessels formation for tissue remodeling and inhibition of anti-apoptotic signals. Vascular endothelial growth factor (VEGF) is important for vascular development in physiological
Autor:
Marlena Galazka, Albert Jaworski, Bartlomiej Zerek, Lukasz Kutner, Katarzyna Wiciejowska, Wojciech Strozek, Michal Szymanik, Anna Pieczykolan, Piotr Rózga, Malgorzata Teska-Kaminska, Jerzy Pieczykolan, Sebastian Pawlak
Publikováno v:
Cancer Research. 73:5488-5488
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) is a promising antitumor agent, but its clinical utility in human malignancies is limited by the resistance mechanism evolved in many cancers types, including overexpresion of anti
Autor:
Marlena Galazka, Piotr Rózga, Lukasz Kutner, Neli Kahmakowa Trojanowska, Bartlomiej Zerek, Jerzy Pieczykolan, Malgorzata Teska Kaminska, Katarzyna Wiciejowska, Wojciech Strozek, Sebastian Pawlak, Michal Szymanik, Albert Jaworski, Anna Pieczykolan, Anna Grochot Przeczek
Publikováno v:
Cancer Research. 73:5073-5073
One of the most important mechanisms of tumorgenesis is formation of new blood vessels and tissue remodeling. Vascular endothelial growth factor (VEGF) is one of the most important and widely studied proangiogenic factors, that has an important role