Výsledky vyhledávání - "Wojciech Puławski"

Akademický článek

Male rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning

Autor: Krzysztof Hubert Olszyński, Rafał Polowy, Agnieszka Diana Wardak, Izabela Anna Łaska, Aneta Wiktoria Grymanowska, Wojciech Puławski, Olga Gawryś, Michał Koliński, Robert Kuba Filipkowski

Publikováno v: eLife, Vol 12 (2024)

Rats are believed to communicate their emotional state by emitting two distinct types of ultrasonic vocalizations. The first is long ‘22-kHz’ vocalizations (>300 ms, 32 kHz), often frequency-modulated, in appetitive situations. Here, we describe

Externí odkaz: https://doaj.org/article/f1d91ebcaa9441fba1e63f83f6584844

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Akademický článek

Revisiting the conformational state of albumin conjugated to gold nanoclusters: A self-assembly pathway to giant superstructures unraveled.

Autor: Michał Kluz, Hanna Nieznańska, Robert Dec, Igor Dzięcielewski, Bartosz Niżyński, Grzegorz Ścibisz, Wojciech Puławski, Grzegorz Staszczak, Ewelina Klein, Julita Smalc-Koziorowska, Wojciech Dzwolak

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0218975 (2019)

Bovine serum albumin (BSA) is often employed as a proteinaceous component for synthesis of luminescent protein-stabilized gold nanoclusters (AuNC): intriguing systems with many potential applications. Typically, the formation of BSA-AuNC conjugate oc

Externí odkaz: https://doaj.org/article/cc0ade19bd0242b4b42b65d915dd99d3

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Virtual Quasi-2D Intermediates as Building Blocks for Plausible Structural Models of Amyloid Fibrils from Proteins with Complex Topologies: A Case Study of Insulin

Autor: Wojciech Puławski, Wojciech Dzwolak

Publikováno v: Langmuir. 38:7024-7034

Conformational transitions of globular proteins into amyloid fibrils are complex multistage processes exceedingly challenging to simulate using molecular dynamics (MD). Slow monomer diffusion rates and rugged free energy landscapes disfavor swift sel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68512b3a9bef89bb924ad7fd12f964f
https://doi.org/10.1021/acs.langmuir.2c00699

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Rats emit aversive 44-kHz ultrasonic vocalizations during prolonged Pavlovian fear conditioning

Autor: Krzysztof H. Olszyński, Rafał Polowy, Agnieszka D. Wardak, Izabela A. Łaska, Aneta W. Grymanowska, Wojciech Puławski, Olga Gawryś, Michał Koliński, Robert K. Filipkowski

Rats are believed to communicate their emotional state by emitting two distinct types of ultrasonic vocalizations. The first is long “22-kHz” vocalizations (>300 ms, 32 kHz), often frequency-modulated, in appetitive situations. Here we are first

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::411cd0461da900b540a7b36cb4a17732
https://doi.org/10.1101/2023.04.06.535936

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Self-assembly of insulin-derived chimeric peptides into two-component amyloid fibrils: the role of Coulombic interactions

Autor: Mateusz Fortunka, Robert Dec, Wojciech Puławski, Marcin Guza, Wojciech Dzwolak

Canonical amyloid fibrils are composed of covalently identical polypeptide chains. Here, we employ kinetic assays, atomic force microscopy (AFM), infrared spectroscopy, circular dichroism (CD), and molecular dynamics (MD) to study fibrillization patt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4edf4521529698e5824fb0679126f202
https://doi.org/10.26434/chemrxiv-2023-jg187

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Forced amyloidogenic cooperativity of structurally incompatible peptide segments: Fibrillization behavior of highly aggregation-prone A-chain fragment of insulin coupled to all-L, and alternating L/D octaglutamates

Autor: Robert Dec, Róża Okoń, Wojciech Puławski, Matylda Wacławska, Wojciech Dzwolak

Self-aggregation of individual polypeptide chains into amyloid fibrils is driven by interactions between amyloidogenic segments of whole proteins. The interplay between aggregation-prone and aggregation-resistant fragments within a single polypeptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c7a48ef918e88a168561fa93a33cb23
https://doi.org/10.26434/chemrxiv-2022-3j0fg

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Reversible Freeze-Induced β-Sheet-to-Disorder Transition in Aggregated Homopolypeptide System

Autor: Mateusz Fortunka, Marcin Guza, Matylda Wacławska, Robert Dec, Wojciech Puławski, Grzegorz Ścibisz, Wojciech Dzwolak

Publikováno v: The journal of physical chemistry. B. 123(43)

Conformational transitions involving aggregated proteins or peptides are of paramount biomedical and biotechnological importance. Here, we report an unusual freeze-induced structural reorganization within a β-sheet-rich ionic coaggregate of poly(l-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0bcd887332d76592b312b647a2a2ec
https://pubmed.ncbi.nlm.nih.gov/31584823

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