Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wojciech Niewiarowski"'
Autor:
E Zielińska, Wojciech Niewiarowski, Grzegorz Rebowski, Jerzy Bodalski, Mianowska K, Skretkowicz J, Sekulska M
Publikováno v:
Pharmacy World and Science. 20:123-130
The pathogenesis of hypersensitivity to trimethoprim‐sulfamethoxazole (TMP‐SMX) is supposed to be associated with the slow acetylation phenotype. This pharmacogenetic defect is associated with the mutations of the arylamine N‐acetyltransferase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b10fe6d48b59f10b930fe9aa50939ca
https://doi.org/10.1023/a:1008664707825
https://doi.org/10.1023/a:1008664707825
Publikováno v:
Antisense and Nucleic Acid Drug Development. 7:381-395
A new method of stereoselective preparation of di(2'-deoxy or 2'-OMe)ribonucleoside (3',5')-methanephosphonate 5 is presented. The DBU/LiCl-assisted reaction of 5'-O-DMT-(2'-deoxy or 2'-OMe)ribonucleoside 3'-O-(S-alkyl methanephosphonothioate) 9 with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f76195918165d6e4e839f742833145d
https://doi.org/10.1089/oli.1.1997.7.381
https://doi.org/10.1089/oli.1.1997.7.381
Autor:
Marzena Wojcik, Edyta Gendaszewska, Mirosław Soszyński, Wojciech Niewiarowski, Grzegorz Rebowski, Grzegorz Bartosz, Malgorzata Boczkowska
Publikováno v:
ResearcherID
Scopus-Elsevier
Scopus-Elsevier
Multidrug resistance-associated protein (MRP1) is a transmembrane pump protein responsible for the efflux of chemotherapeutic drugs, an important cause of anticancer treatment failure. Trying to circumvent MRP-mediated resistance we designed and synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2c0cc63994b73e4bfa4fc51f21b95e
https://pubmed.ncbi.nlm.nih.gov/11995968
https://pubmed.ncbi.nlm.nih.gov/11995968
Autor:
Barbara Mikołajczyk, W. Goss, Edyta Gendaszewska, Grzegorz Rebowski, Wojciech Niewiarowski, Marzena Wojcik, Grzegorz Bartosz, Mirosław Soszyński
Publikováno v:
Acta biochimica Polonica. 47(4)
Multidrug resistance-associated protein (MRP1) causes cellular drug resistance in several cancer cell lines. In this paper we show that antisense oligonucleotides decrease MRP1 expression in human leukaemia cells. We investigated biological activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::342d78565463806160f7fad498b26d75
https://pubmed.ncbi.nlm.nih.gov/11996108
https://pubmed.ncbi.nlm.nih.gov/11996108
Expression of the multidrug resistance-associated protein (mrp) gene in chronic lymphocytic leukemia
Autor:
Tadeusz Robak, PrzemysŁaw Juszczyński, Wojciech Niewiarowski, E. Krykowski, Krzysztof Warzocha
Publikováno v:
Leukemialymphoma. 43(1)
In order to define more accurately the role of multidrug resistance (MDR)-related protein (mrp) gene in chronic lymphocytic leukemia (CLL), we addressed the question of its expression pattern in isolated peripheral blood B lymphocytes in seven health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c6fc9868514bcf6376aae5665c4484
https://pubmed.ncbi.nlm.nih.gov/11908721
https://pubmed.ncbi.nlm.nih.gov/11908721
Autor:
Wojciech Niewiarowski, Agnieszka Sierzchala, Xian-Bin Yang, Marek Sochacki, Michał W. Wieczorek, Wojciech J. Stec, Konrad Misiura
Publikováno v:
The Journal of organic chemistry. 63(20)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::860e7fafd255cc77ea9824892efb074a
https://pubmed.ncbi.nlm.nih.gov/11672339
https://pubmed.ncbi.nlm.nih.gov/11672339
Autor:
Iwona Matusiak, Wojciech Niewiarowski, Elżbieta Zielińska, Jerzy Bodalski, Wojciech Bolanowski
Publikováno v:
Pediatric research. 45(3)
The present study focused on evaluation of the extent to which genotype coding for N-acetyltransferase agrees with acetylation phenotype in children at various ages. In 82 Caucasian children aged from 1 mo to 17 y (57 boys and 25 girls) and including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4e94e9b953b0bad07209d13b642a482
https://pubmed.ncbi.nlm.nih.gov/10088662
https://pubmed.ncbi.nlm.nih.gov/10088662
Publikováno v:
European journal of clinical pharmacology. 54(9-10)
Objective: The evaluation of the importance of the genetically determined acetylation defect for the development of adverse reactions to co-trimoxazole in children. Methods: The study comprised 48 children aged 3 months to 3 years, who were being tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d5bf71fd1e1c718538ba7e969fce6a
https://pubmed.ncbi.nlm.nih.gov/9923584
https://pubmed.ncbi.nlm.nih.gov/9923584
Autor:
Wojciech Niewiarowski, Elżbieta Zielińska, Grzegorz Rebowski, Jerzy Bodalski, Wojciech Bolanowski, Anna Stańczyk
Publikováno v:
Clinical pharmacology and therapeutics. 62(6)
The overrepresentation of phenotypically slow acetylators among patients with atopic allergy has been reported in previous studies. The N-acetyltransferase coding gene has not yet been investigated in allergic diseases. This study was designed to det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::280e7fc0bbab9e886ba3076702f787f1
https://pubmed.ncbi.nlm.nih.gov/9433392
https://pubmed.ncbi.nlm.nih.gov/9433392
Publikováno v:
Tetrahedron Letters. 23:4289-4292
The synthesis and separation of diastereomere of protected thymidyl(3′–5′)thymidyl 0,0-phosphoranilidate (4) allowed to obtain in the stereospecific manner title compounds 5, whose absolute configuration at P atom was assigned enzymatically. TP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b257c347a7e2eaf823cda7a12f7dad73
https://doi.org/10.1016/s0040-4039(00)88727-4
https://doi.org/10.1016/s0040-4039(00)88727-4