Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Wojciech Krężel"'
Autor:
Volker Kittke, Chen Zhao, Daniel D. Lam, Philip Harrer, Wojciech Krezel, Barbara Schormair, Konrad Oexle, Juliane Winkelmann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract MEIS1 and MEIS2 encode highly conserved homeodomain transcription factors crucial for developmental processes in a wide range of tissues, including the brain. They can execute redundant functions when co-expressed in the same cell types, but
Externí odkaz:
https://doaj.org/article/f40b896ed78140559ec3195cbe7f6fd2
Autor:
Agnieszka Krzyżosiak, Anna Podleśny-Drabiniok, Belén Vaz, Rosana Alvarez, Ralph Rühl, Angel R. de Lera, Wojciech Krężel
Publikováno v:
Neurobiology of Stress, Vol 15, Iss , Pp 100375- (2021)
9-cis-13,14-dihydroretinoic acid (9CDHRA), acts as an endogenous ligand of the retinoid X receptors (RXRs), and is an active form of a suggested new vitamin, vitamin A5/X. Nutritional-relevance of this pathway as well as its detailed role in vertebra
Externí odkaz:
https://doaj.org/article/89159deb5007493a928f8d5c507644ce
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
The interaction of long circulating drugs with biological molecules might trigger harmful side effects. Here, the authors design an anticoagulant compound that can be deactivatedin vivo using click chemistry, paving the way to the design of drugs wit
Externí odkaz:
https://doaj.org/article/ebda2b9fe32443d9b94c7789c9666492
Autor:
Vito Antonio Baldassarro, Wojciech Krężel, Mercedes Fernández, Brigitte Schuhbaur, Luciana Giardino, Laura Calzà
Publikováno v:
Stem Cell Research, Vol 37, Iss , Pp - (2019)
Oligodendrocyte precursor cells (OPCs) differentiation from multipotent neural stem cells (NSCs) into mature oligodendrocytes is driven by thyroid hormone and mediated by thyroid hormone receptors (TRs). We show that several nuclear receptors display
Externí odkaz:
https://doaj.org/article/a339edd0ad754569a5d13736ede7fe6d
Autor:
Joanna Sobska, Magdalena Waszkielewicz, Anna Podleśny-Drabiniok, Joanna Olesiak-Banska, Wojciech Krężel, Katarzyna Matczyszyn
Publikováno v:
Nanomaterials, Vol 11, Iss 5, p 1066 (2021)
Gold nanoparticles hold a great promise for both clinical and preclinical applications. The major factors impeding such applications are toxicity of new nanomaterials including e.g., pro-apoptotic activities or inflammatory effects, but also their po
Externí odkaz:
https://doaj.org/article/9d6e6220499343e6b75167cc57816124
Autor:
Ralph Rühl, Agnieszka Krzyżosiak, Anna Niewiadomska-Cimicka, Natacha Rochel, Lajos Szeles, Belén Vaz, Marta Wietrzych-Schindler, Susana Álvarez, Monika Szklenar, Laszlo Nagy, Angel R de Lera, Wojciech Krężel
Publikováno v:
PLoS Genetics, Vol 11, Iss 6, p e1005213 (2015)
The retinoid X receptors (RXRs) are ligand-activated transcription factors which heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of (patho)-physiological processes. Although synthetic RXR ligands are developed
Externí odkaz:
https://doaj.org/article/a8a62018524c4643af5c0e9dd6f976d2
Autor:
Marion Ciancia, Monika Rataj-Baniowska, Nicolas Zinter, Vito Antonio Baldassarro, Valérie Fraulob, Anne-Laure Charles, Rosana Alvarez, Shin-ichi Muramatsu, Angel R. de Lera, Bernard Geny, Pascal Dollé, Anna Niewiadomska-Cimicka, Wojciech Krężel
Publikováno v:
Progress in neurobiology. 212
Retinoic acid is a powerful regulator of brain development, however its postnatal functions only start to be elucidated. We show that retinoic acid receptor beta (RARβ), is involved in neuroprotection of striatopallidal medium spiny neurons (spMSNs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97c9c72699c58bcd43fde7489db39dad
https://pubmed.ncbi.nlm.nih.gov/35151792
https://pubmed.ncbi.nlm.nih.gov/35151792
Autor:
Christina Sahyoun, Wojciech Krezel, César Mattei, Jean-Marc Sabatier, Christian Legros, Ziad Fajloun, Mohamad Rima
Publikováno v:
Biology, Vol 11, Iss 6, p 888 (2022)
The complications following snake bite envenoming are due to the venom’s biological activities, which can act on different systems of the prey. These activities arise from the fact that snake venoms are rich in bioactive molecules, which are also o
Externí odkaz:
https://doaj.org/article/6648a183f7074e01bba5a62113ee3059
Autor:
Sara Bonzano, Isabella Crisci, Anna Podlesny-Drabiniok, Chiara Rolando, Wojciech Krezel, Michèle Studer, Silvia De Marchis
Publikováno v:
Cell Reports, Vol 24, Iss 2, Pp 329-341 (2018)
Summary: In the dentate gyrus (DG) of the mouse hippocampus, neurogenesis and astrogliogenesis persist throughout life. Adult-born neurons and astrocytes originate from multipotent neural stem cells (NSCs) whose activity is tightly regulated within t
Externí odkaz:
https://doaj.org/article/84993f6d83024065a3f2c905e7204246
Publikováno v:
Viruses, Vol 7, Iss 5, Pp 2308-2320 (2015)
Among Herpesviruses, Human Cytomegalovirus (HCMV or HHV-5) represents a major threat during congenital or neonatal infections, which may lead to encephalitis with serious neurological consequences. However, as opposed to other less prevalent pathogen
Externí odkaz:
https://doaj.org/article/4ceed23eb5ba48f88616b9d3dff848c8