Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Wojciech K. Kasprzak"'
Autor:
Lukasz T. Olenginski, Wojciech K. Kasprzak, Solomon K. Attionu, Bruce A. Shapiro, Theodore K. Dayie
Publikováno v:
Molecules, Vol 28, Iss 4, p 1803 (2023)
The global burden imposed by hepatitis B virus (HBV) infection necessitates the discovery and design of novel antiviral drugs to complement existing treatments. One attractive and underexploited therapeutic target is ε, an ~85-nucleotide (nt) cis-ac
Externí odkaz:
https://doaj.org/article/4892b6cd81214f32817555a7f2b2fc72
Autor:
Xavier Bofill-De Ros, Wojciech K. Kasprzak, Yuba Bhandari, Lixin Fan, Quinn Cavanaugh, Minjie Jiang, Lisheng Dai, Acong Yang, Tie-Juan Shao, Bruce A. Shapiro, Yun-Xing Wang, Shuo Gu
Publikováno v:
Cell Reports, Vol 26, Iss 2, Pp 447-459.e4 (2019)
Summary: MicroRNA (miRNA) processing begins with Drosha cleavage, the fidelity of which is critical for downstream processing and mature miRNA target specificity. To understand how pri-miRNA sequence and structure influence Drosha cleavage, we studie
Externí odkaz:
https://doaj.org/article/ddfe0f6fd3994ce482d993e45c7ea9a6
Publikováno v:
Molecules, Vol 23, Iss 12, p 3329 (2018)
Cells frequently simultaneously express RNAs and cognate antisense transcripts without necessarily leading to the formation of RNA duplexes. Here, we present a novel transcriptome-wide experimental approach to ascertain the presence of accessible dou
Externí odkaz:
https://doaj.org/article/251cc2fa734d493a9533e06254580acf
Publikováno v:
Nucleic Acids Research. 50:1601-1619
Canonical eukaryotic mRNA translation requires 5′cap recognition by initiation factor 4E (eIF4E). In contrast, many positive-strand RNA virus genomes lack a 5′cap and promote translation by non-canonical mechanisms. Among plant viruses, PTEs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8420a34f48bab61ed8ed33d5c42084
https://doi.org/10.1093/nar/gkac007
https://doi.org/10.1093/nar/gkac007
Autor:
Monalisa Swain, Abeer A Ageeli, Wojciech K Kasprzak, Mi Li, Jennifer T Miller, Joanna Sztuba-Solinska, John S Schneekloth, Deepak Koirala, Joseph Piccirili, Americo J Fraboni, Ryan P Murelli, Alexander Wlodawer, Bruce A Shapiro, Nathan Baird, Stuart F J Le Grice
Publikováno v:
Nucleic Acids Res
Cellular and virus-coded long non-coding (lnc) RNAs support multiple roles related to biological and pathological processes. Several lncRNAs sequester their 3′ termini to evade cellular degradation machinery, thereby supporting disease progression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dea3706807e0dc1990b7e0a13320f8
https://doi.org/10.1093/nar/gkab1170
https://doi.org/10.1093/nar/gkab1170
Autor:
Wojciech K. Kasprzak, Bruce A. Shapiro
Publikováno v:
Methods in Molecular Biology ISBN: 9781071626863
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d42dbdd77afdcc66519d20bd2592831
https://doi.org/10.1007/978-1-0716-2687-0_6
https://doi.org/10.1007/978-1-0716-2687-0_6
Autor:
Wojciech K, Kasprzak, Bruce A, Shapiro
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2568
Recognition of the growing importance of RNA as a target for therapeutic or diagnostic ligands brings the importance of computational predictions of docking poses to such receptors to the forefront. Most docking programs have been optimized for prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d602051ca39c617b67f3d6289ec40446
https://pubmed.ncbi.nlm.nih.gov/36227563
https://pubmed.ncbi.nlm.nih.gov/36227563
Autor:
My-Tra Le, Wojciech K Kasprzak, Taejin Kim, Feng Gao, Megan YL Young, Xuefeng Yuan, Bruce A Shapiro, Joonil Seog, Anne E Simon
Publikováno v:
eLife, Vol 6 (2017)
Turnip crinkle virus contains a T-shaped, ribosome-binding, translation enhancer (TSS) in its 3’UTR that serves as a hub for interactions throughout the region. The viral RNA-dependent RNA polymerase (RdRp) causes the TSS/surrounding region to unde
Externí odkaz:
https://doaj.org/article/8c74356cd4e8482fa9a774dd09782c15
Autor:
Lukasz T, Olenginski, Wojciech K, Kasprzak, Christina, Bergonzo, Bruce A, Shapiro, Theodore K, Dayie
Publikováno v:
Journal of Molecular Biology. 434:167633
Human hepatitis B virus (HBV) replication is initiated by the binding of the viral polymerase (P) to epsilon (ε), an ≈85-nucleotide (nt) cis-acting regulatory stem-loop RNA located at the 5'-end of the pre-genomic RNA (pgRNA). This interaction tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e902bea27e8e56d9a4c14e06a2dfbc
https://doi.org/10.1016/j.jmb.2022.167633
https://doi.org/10.1016/j.jmb.2022.167633