Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Wojciech J, Szczepek"'
Autor:
Iwona Dams, Anna Ostaszewska, Maria Puchalska, Justyna Chmiel, Piotr Cmoch, Iwona Bujak, Agata Białońska, Wojciech J. Szczepek
Publikováno v:
Molecules, Vol 20, Iss 12, Pp 21346-21363 (2015)
During the process development for multigram-scale synthesis of olmesartan medoxomil (OM), two principal regioisomeric process-related impurities were observed along with the final active pharmaceutical ingredient (API). The impurities were identifie
Externí odkaz:
https://doaj.org/article/597524469ce24822a97c25c3abeac4a0
Autor:
Marcin Górecki, Jadwiga Frelek, Roman Luboradzki, Wojciech J. Szczepek, Anna Ostaszewska, Alicja Dziedzic
Publikováno v:
Steroids. 124:72-80
Four crystalline dutasteride hydrochloride hydrate solvates containing respectively methanol, ethanol, acetone and acetonitrile molecules were obtained. All samples were characterized by extensive spectroscopic analysis with infrared spectroscopy (FT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b3c751ecad7e1766ebd814239dc857
https://doi.org/10.1016/j.steroids.2017.05.014
https://doi.org/10.1016/j.steroids.2017.05.014
Autor:
Marcin Górecki, Ryszard K. Wojcieszczyk, Wojciech J. Szczepek, Marcin Kwit, Jadwiga Frelek, Roman Luboradzki, Michał F. Rode, Aleksandra Butkiewicz
Publikováno v:
RSC Adv.. 4:43977-43993
In the present work, the validity of sector and helicity rules correlating the stereostructure of cis-enones containing the 2-methylenecyclopentanone unit with the sign of the nπ* Cotton effect (CE) observed in their electronic circular dichroism (E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4152dd82bcf723f238b021c094d3e047
https://doi.org/10.1039/c4ra04991h
https://doi.org/10.1039/c4ra04991h
Autor:
Ewa Jabłońska, Marcin Górecki, Zofia Urbańczyk-Lipkowska, Anna Kruszewska, Jadwiga Frelek, Wojciech J. Szczepek, Michael Gerards, Jacek W. Morzycki, Agata Suszczyńska
Publikováno v:
The Journal of Organic Chemistry. 72:2906-2916
We describe here an application of the practical, simple, and reliable approach for the determination of the absolute configuration of sterically demanding tert/tert vic-diols. According to this method, it is only necessary to mix dimolybdenum tetraa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01aeda03fcf41d5fd9d16f88d4f5c10
https://doi.org/10.1021/jo062445x
https://doi.org/10.1021/jo062445x
Publikováno v:
Journal of pharmaceutical sciences. 104(11)
In this work, for the first time we report complementary structural and spectral studies of linezolid and its synthetic precursors (R)-N-{3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxooxazolidin-5-yl}methanol and (R)-N-{3-[3-fluoro-4-(morpholin-4-yl)phe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::023504d6d1262e4f52668e1db71870ab
https://pubmed.ncbi.nlm.nih.gov/26344859
https://pubmed.ncbi.nlm.nih.gov/26344859
Autor:
Wojciech J. Szczepek, Marcin Górecki, Alicja Dziedzic, Jadwiga Frelek, Roman Luboradzki, Bohdan Kamieński, Ewa Jabƚońska, Ryszard K. Wojcieszczyk
Publikováno v:
Journal of pharmaceutical sciences. 104(5)
The pure polymorphic forms I, II, and III of finasteride were prepared and their purity was confirmed by FTIR, differential scanning calorimetry, and X-ray powder diffraction measurements. The preparation experiments demonstrated that the desolvation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fdf4274ff07c0d0f59dbbef7893cbbb
https://pubmed.ncbi.nlm.nih.gov/25648836
https://pubmed.ncbi.nlm.nih.gov/25648836
Autor:
Jadwiga Frelek, William S. Sheldrick, Wojciech J. Szczepek, Edyta Wieteska, Jacek Jagodzinski, Heike Meyer‐Figge
Publikováno v:
Chirality. 13:313-321
The circular dichroism (CD) of the in situ-formed Rh2(OCOCF3)4 complexes of sterically hindered, secondary lanostane alcohols was investigated. The main object of the present studies are derivatives of 3beta-, 7alpha-, 7beta-, and 11beta-hydroxylanos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e918000cfe7b4c84a53af496cf2cc1df
https://doi.org/10.1002/chir.1037
https://doi.org/10.1002/chir.1037
Autor:
Jadwiga Frelek, Wojciech J. Szczepek
Publikováno v:
Tetrahedron: Asymmetry. 10:1507-1520
The circular dichroism (CD) of in situ formed complexes of steroidal substituted secondary and tertiary alcohols with [Rh2(OCOCF3)4] have been investigated. The applicability of the bulkiness rule, developed for unsubstituted secondary alcohols and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe1972e940d247329422b4d08eab15d7
https://doi.org/10.1016/s0957-4166(99)00115-9
https://doi.org/10.1016/s0957-4166(99)00115-9
Publikováno v:
Bulletin of the Chemical Society of Ethiopia, Vol 1, Iss 1, Pp 18-28 (1987)
Bull.Chem.Soc.Ethiop.,1(1),18-28(1987).
Externí odkaz:
https://doaj.org/article/23534c6b27e748079aabd4853de534b1
Autor:
Walter Frank, Hans Peter Weiss, Joachim Brechtel, Jadwiga Frelek, Wojciech J. Szczepek, Bernd Schultheis, Guido J. Reiss, Hans-Georg Kuball
Publikováno v:
Journal of the American Chemical Society. 120:7010-7019
The circular dichroism (CD) and circular dichroism of anisotropic samples (ACD) of cisoid enones 3-methyl-3α,5α-3,3‘,4‘,5‘-tetrahydrobenzo[2,3]cholest-2-en-1-one (4) and its 3β-diastereoisomer 7 have been investigated. The relation between s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f16ddc623c69c67ba1835a3eef6f8035
https://doi.org/10.1021/ja973076c
https://doi.org/10.1021/ja973076c