Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Wojciech I. Swiatek"'
Autor:
Xiaoying Wu, Donna Romero, Wojciech I. Swiatek, Irene Dorweiler, Chintan K. Kikani, Hana Sabic, Ben S. Zweifel, John McKearn, Jeremy T. Blitzer, G. Allen Nickols, Jared Rutter
Publikováno v:
Cell Reports, Vol 8, Iss 1, Pp 242-255 (2014)
Elevated hepatic synthesis of fatty acids and triglycerides, driven by hyperactivation of the SREBP-1c transcription factor, has been implicated as a causal feature of metabolic syndrome. SREBP-1c activation requires the proteolytic maturation of the
Externí odkaz:
https://doaj.org/article/bcfb358796ac4baaa0adfe00f7c46801
Publikováno v:
Hepatology Communications, Vol 4, Iss 5, Pp 696-707 (2020)
Hepatology Communications
Hepatology Communications
Hyperactivation of sterol regulatory element binding protein 1c (SREBP‐1c), which transcriptionally induces expression of enzymes responsible for de novo lipogenesis and triglyceride (TG) formation, is implicated in nonalcoholic fatty liver disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee01b82cb0a1b6b875a691bd4c07b6c
https://doi.org/10.1002/hep4.1498
https://doi.org/10.1002/hep4.1498
Autor:
Ahmad A. Cluntun, Xuejing Yu, Corey N. Cunningham, Sarah Fogarty, Shannon Merx, Wojciech I. Swiatek, Bai Luo, Aspasia Thodou Krokidi, William L. Holland, Alex J. Bott, Gregory S. Ducker, Tyler Van Ry, Sophia Skedros, Kristofor A. Olson, Rachit Badolia, Sean M. Tatum, Stavros G. Drakos, Sandra Lettlova, Sutip Navankasattusas, Jared Rutter, Iosif Taleb, Nikolaos A. Diakos, Stephen H. McKellar, Thirupura S. Shankar, James E. Cox, Jordan A. Berg, K. Mark Parnell
Publikováno v:
Cell Metab
The metabolic rewiring of cardiomyocytes is a widely accepted hallmark of heart failure (HF). These metabolic changes include a decrease in mitochondrial pyruvate oxidation and an increased export of lactate. We identify the Mitochondrial Pyruvate Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68e7e4180bbb5a90d441073b0cc337d
https://doi.org/10.1016/j.cmet.2020.12.003
https://doi.org/10.1016/j.cmet.2020.12.003