Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Wojciech Goch"'
Publikováno v:
Molecules, Vol 27, Iss 2, p 457 (2022)
Background: The stability of a drug or metabolites in biological matrices is an essential part of bioanalytical method validation, but the justification of its sample size (replicates number) is insufficient. The international guidelines differ in re
Externí odkaz:
https://doaj.org/article/e6a4e05174b947328918eb428326966b
Publikováno v:
Molecules, Vol 25, Iss 18, p 4177 (2020)
Tetrathiolate zinc fingers are potential targets of oxidative assault under cellular stress conditions. We used the synthetic 37-residue peptide representing the tetrathiolate zinc finger domain of the DNA repair protein XPA, acetyl-DYVICEECGKEFMSYLM
Externí odkaz:
https://doaj.org/article/b5e92531f88048d3b41a59aff20e0d5a
Autor:
Wojciech Goch, Wojciech Bal
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170749 (2017)
The interactions between the Aβ1-40 molecules species and the copper ions (Cu(II)) were intensively investigated due to their potential role in the development of the Alzheimer Disease (AD). The rate and the mechanism of the Cu(II)-Aβ complexes for
Externí odkaz:
https://doaj.org/article/d0e6aab473f5457fa7e2805b71b0a3b8
Autor:
Elena Atrián-Blasco, Wojciech Bal, Ewelina Stefaniak, Wojciech Goch, Christelle Hureau, Laurent Sabater
Publikováno v:
Chemistry – A European Journal. 27:2798-2809
Alzheimer's disease (AD) is one of the most common of the multifactorial diseases and is characterized by a range of abnormal molecular processes, such as the accumulation of extracellular plaques containing the amyloid-β (Aβ) peptides and dyshomeo
Autor:
Chiara Borsari, Erhan Keles, Jacob A. McPhail, Alexander Schaefer, Rohitha Sriramaratnam, Wojciech Goch, Thorsten Schaefer, Martina De Pascale, Wojciech Bal, Matthias Gstaiger, John E. Burke, Matthias P. Wymann
Publikováno v:
Journal of the American Chemical Society, 144 (14)
Journal of the American Chemical Society
Journal of the American Chemical Society
Covalent protein kinase inhibitors exploit currently noncatalytic cysteines in the adenosine 5′-triphosphate (ATP)-binding site via electrophiles directly appended to a reversible-inhibitor scaffold. Here, we delineate a path to target solvent-expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4ac7a3a87ebe57f8fc665894307933
https://hdl.handle.net/20.500.11850/544544
https://hdl.handle.net/20.500.11850/544544
Autor:
Wojciech Goch, Wojciech Bal
Publikováno v:
The Journal of Physical Chemistry A. 124:1421-1428
The stochastic nature of chemical reaction and impact of the stochasticity on their evolution is soundly documented. Both theoretical predictions and emerging experimental evidence indicate the influence of stochastic effects on the equilibrium state
Publikováno v:
Chemistry – A European Journal
Autor:
Ewelina, Stefaniak, Elena, Atrian-Blasco, Wojciech, Goch, Laurent, Sabater, Christelle, Hureau, Wojciech, Bal
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 27(8)
Alzheimer's disease (AD) is one of the most common of the multifactorial diseases and is characterized by a range of abnormal molecular processes, such as the accumulation of extracellular plaques containing the amyloid-β (Aβ) peptides and dyshomeo
Publikováno v:
Inorganic chemistry. 58(21)
The intracellular exchangeable Zn(II) is usually measured with synthetic fluorescent zinc sensors. 4',5'-Bis[bis(2-pyridylmethyl)aminomethyl]-2',7'-dichlorofluorescein (Zinpyr-1) is a sensor containing the fluorescein platform and a duplicated chelat
Publikováno v:
Molecules, 25 (18), Art. Nr.: 4177
Molecules
Volume 25
Issue 18
Molecules, Vol 25, Iss 4177, p 4177 (2020)
Molecules
Volume 25
Issue 18
Molecules, Vol 25, Iss 4177, p 4177 (2020)
Tetrathiolate zinc fingers are potential targets of oxidative assault under cellular stress conditions. We used the synthetic 37-residue peptide representing the tetrathiolate zinc finger domain of the DNA repair protein XPA, acetyl-DYVICEECGKEFMSYLM