Zobrazeno 1 - 10
of 472
pro vyhledávání: '"Wohlfarth, P."'
Autor:
Jonas Wohlfarth, Corinna Kosnopfel, Dominic Faber, Marion Berthold, Claudia Siedel, Melissa Bernhardt, Andreas Schlosser, Tyler Aprati, David Liu, David Schrama, Roland Houben, Dirk Schadendorf, Matthias Goebeler, Svenja Meierjohann, Bastian Schilling
Publikováno v:
Molecular Oncology, Vol 18, Iss 10, Pp 2449-2470 (2024)
Immunotherapy has achieved tremendous success in melanoma. However, only around 50% of advanced melanoma patients benefit from immunotherapy. Cyclin‐dependent kinase inhibitor 2A (CDKN2A), encoding the two tumor‐suppressor proteins p14ARF and p16
Externí odkaz:
https://doaj.org/article/329322a45f3c4cab9aaa97867023c73c
Autor:
Frieder Fuchs, Kyriaki Xanthopoulou, Tessa Burgwinkel, Rocío Arazo del Pino, Esther Wohlfarth, Florian Pavlu, Ralf M. Hagen, Paul G. Higgins
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 39, Iss , Pp 184-188 (2024)
Objective: To molecularly characterize several extensively drug-resistant isolates from a single hospital admission screening of a war-injured patient from Ukraine. Methods: Admission screening included swabs from skin, wounds, catheters, nasopharyng
Externí odkaz:
https://doaj.org/article/07a1d2dc0c624313b8e07f951eafa8fb
Autor:
Tom Haufschild, Nicolai Kallscheuer, Jonathan Hammer, Timo Kohn, Moses Kabuu, Mareike Jogler, Nicole Wohlfarth, Manfred Rohde, Muriel C. F. van Teeseling, Christian Jogler
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Members of the phylum Gemmatimonadota can account for up to 10% of the phylogenetic diversity in bacterial communities. However, a detailed investigation of their cell biology and ecological roles is restricted by currently only six characte
Externí odkaz:
https://doaj.org/article/1d0f3c1676754262875cdb31577d5f6a
Publikováno v:
Icarus (April 2023) Volume:394
The study of meter and sub-meter scale geological features, especially boulders and boulder fields, on the surface of airless bodies can provide insight into the evolution of the regolith and the contribution of various processes to its formation. Pr
Externí odkaz:
http://arxiv.org/abs/2301.09885
Autor:
Benny Wohlfarth, Noa Linder, Felix Michael Schmitz, Roman Hari, Achim Elfering, Sissel Guttormsen
Publikováno v:
Swiss Medical Weekly, Vol 154, Iss 7 (2024)
AIMS OF THE STUDY: This research aimed to investigate the self-directed learning (SDL) habits of Swiss general practitioners from the German-speaking part of Switzerland, understanding how they acquire new knowledge, exploring the impact of the COVID
Externí odkaz:
https://doaj.org/article/7e86d7a36680455d9f2c8d76810b9018
Autor:
A. Hackl, E. Nüsken, J. Voggel, S. E. D. Abo Zed, J. Binz-Lotter, D. Unnersjö-Jess, C. Müller, G. Fink, K. Bohl, E. Wiesner, P. Diefenhardt, C. Dafinger, H. Chen, M. Wohlfarth, R.-U. Müller, M. J. Hackl, B. Schermer, K.-D. Nüsken, L. T. Weber
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Mycophenolate mofetil (MMF) is applied in proteinuric kidney diseases, but the exact mechanism of its effect on podocytes is still unknown. Our previous in vitro experiments suggested that MMF can ameliorate podocyte damage via restoration o
Externí odkaz:
https://doaj.org/article/a4500ced5bc04882ae31785389e4f496
Autor:
Corinna Kosnopfel, Simone Wendlinger, Heike Niessner, Johannes Siewert, Tobias Sinnberg, Angelika Hofmann, Jonas Wohlfarth, David Schrama, Marion Berthold, Claudia Siedel, Birgit Sauer, Aarthi Jayanthan, Georg Lenz, Sandra E. Dunn, Bastian Schilling, Birgit Schittek
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-14 (2023)
Abstract Background The mitogen-activated protein kinase (MAPK) signaling pathway is frequently hyperactivated in malignant melanoma and its inhibition has proved to be an efficient treatment option for cases harboring BRAFV600 mutations (BRAFMut). H
Externí odkaz:
https://doaj.org/article/0723a98be8b54729b41f40fee5a42d27
Autor:
Wunderling, Nico, Krönke, Jonathan, Wohlfarth, Valentin, Kohler, Jan, Heitzig, Jobst, Staal, Arie, Willner, Sven, Winkelmann, Ricarda, Donges, Jonathan F.
Publikováno v:
European Physical Journal Special Topics 230, 3163-3176 (2021)
Tipping elements occur in various systems such as in socio-economics, ecology and the climate system. In many cases, the individual tipping elements are not independent from each other, but they interact across scales in time and space. To model syst
Externí odkaz:
http://arxiv.org/abs/2011.02031
Publikováno v:
Medical Education Online, Vol 28, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/3b5c924a6a5c4012af77218d7674562d
Publikováno v:
Antibiotics, Vol 13, Iss 6, p 471 (2024)
Bacteria are a major cause of superficial eye infections, especially in children. The present study aimed to (i) determine the antimicrobial susceptibility patterns of ocular bacterial pathogens recovered in 20 laboratories during the period 2020–2
Externí odkaz:
https://doaj.org/article/7c7a40371b58422484dd2bb7d4baf075