Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors:  Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies

Autor: Jadhav, P. K., Woerner, F. J., Lam, P. Y. S., Hodge, C. N., Eyermann, C. J., Man, H.-W., Daneker, W. F., Bacheler, L. T., Rayner, M. M., Meek, J. L., Erickson-Viitanen, S., Jackson, D. A., Calabrese, J. C., Schadt, M., Chang, C.-H.

Publikováno v: Journal of Medicinal Chemistry; April 23, 1998, Vol. 41 Issue: 9 p1446-1455, 10p

Synthesis of 7-membered cyclic hydroxyguanidines: novel HIV-1 protease inhibitors

Autor: Jadhav, P. K., Woerner, F. J., Man, H.-W.

Publikováno v: Bioorganic & Medicinal Chemistry Letters; 1997, Vol. 7 Issue: 17 p2145-2148, 4p

ChemInform Abstract: Potentially General Synthesis of Polyhydroxyindolizidines.

Autor: JADHAV, P. K., WOERNER, F. J.

Publikováno v: ChemInform; Apr1995, Vol. 26 Issue 17, pno-no, 1p

Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure-activity relationships, and X-ray crystal structure studies.

Autor: Jadhav PK; Chemical and Physical Sciences Department, The DuPont Merck Pharmaceutical Company, Experimental Station, P.O. Box 80500, Wilmington, Delaware 19880-0500, USA. Prabhakar.K.Jadhav@dupontmerck.com, Woerner FJ, Lam PY, Hodge CN, Eyermann CJ, Man HW, Daneker WF, Bacheler LT, Rayner MM, Meek JL, Erickson-Viitanen S, Jackson DA, Calabrese JC, Schadt M, Chang CH

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1998 Apr 23; Vol. 41 (9), pp. 1446-55.