Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Woei Ping Cheng"'
Autor:
Woei Ping Cheng, Ambreen Khan
Publikováno v:
Advances and Challenges in Oral Delivery of Macromolecules. :88-107
Autor:
Clare Hoskins, Anthony D.M. Curtis, Paul Kong Thoo Lin, Christopher M. Barnett, Woei Ping Cheng, Martin R. Lees
Publikováno v:
Pharmaceutical Nanotechnology. 1:224-238
This work was funded by the Institute of Science and Technology in Medicine and the School of Pharmacy, Keele University. The NMR and ICP-OES analysis was carried out in the Lennard-Jones Laboratories in the School of Physical and Geographical Scienc
Publikováno v:
International Journal of Pharmaceutics. 447:150-157
Targeting the gastrointestinal (GI) tract represents a promising strategy for local or systemic delivery of nucleic acid-based therapeutics. The development of a nano-carrier for siRNA delivery via the GI tract would enable localised therapy for a ra
Autor:
Fatme Mawas, Manolya Saydam, Woei Ping Cheng, Rob Tierney, Robert J. Francis, Ambreen Khan, Kirsty MacLellan-Gibson, Nathan Palmer
Publikováno v:
Vaccine. 35(18)
The use of Soluplus® polymeric micelles as a novel adjuvant for tetanus toxoid (TTxd) in transcutaneous immunisation was evaluated. TTxd was added to Soluplus® polymeric micelles to form TTxd-Soluplus® nano-aggregates with a size of 68 nm. Non-adj
Publikováno v:
Therapeutic Delivery. 3:59-79
Comb-shaped amphiphilic polymers are rapidly emerging as an alternative approach to amphiphilic block copolymers for hydrophobic drug solubilization. These polymers consist of a homopolymer or copolymer backbone to which hydrophobic and hydrophilic p
Publikováno v:
Pharmaceutical Research. 29:782-794
To investigate the use of nano self-assemblies formed by polyallylamine (PAA) modified with 5 or 10% mole fluorenylmethoxy carbonyl (Fmoc(5)/(10)), dimethylamino-1-naphthalenesulfonyl (Dansyl(5)/(10)) and 5% mole cholesteryl group (Ch(5)) for oral hy
Publikováno v:
Polymers for Advanced Technologies. 23:710-719
Fluorescent amphiphilic polymers were produced by grafting different types and levels of hydrophobic pendant groups with intrinsic fluorescent properties (fluorenylmethoxy carbonyl (Fmoc), dimethylamino-1-naphthalenesulfonyl (Dansyl), and naphthalene
Autor:
Laurence Tetley, Tanira Aguirre, David J. Brayden, Colin J. Thompson, Sinéad M. Ryan, Woei Ping Cheng
Publikováno v:
Journal of Controlled Release. 147:289-297
The cationic peptide, salmon calcitonin (sCT) was complexed with the cationic amphiphilic polyelectrolyte, poly(allyl)amine, grafted with palmitoyl and quaternary ammonium moieties at pH 5.0 and 7.4 to yield particulates (sCT-QPa). The complexes were
Autor:
Xiaozhong Qu, Laurence Tetley, Colin J. Thompson, Ijeoma F. Uchegbu, Zhenzhong Yang, Caixia Ding, Woei Ping Cheng
Publikováno v:
Colloid and Polymer Science. 286:1511-1526
Twelve novel poly(allylamine) (PAA)-based, comb-shaped amphiphilic polymers have been developed. Hydrophobic groups of cetyl, palmitoyl and cholesteryl were randomly grafted to PAA and quaternisation was carried out on some modified polymers. Polymer
Nanoscience or the science of the very small offers the pharmaceutical scientist a wealth of opportunities. By fabricating at the nanoscale, it is possible to exert unprecedented control on drug activity. This textbook will showcase a variety of na