Výsledky vyhledávání

Periodical

Autor: Friesecke, C., Wodtke, J.

Publikováno v: Der Chirurg; 20240101, Issue: Preprints p1-18, 18p

Enzymological characterization of ⁶⁴Cu-labeled neprilysin substrates and their application for modulating the renal clearance of targeted radiopharmaceuticals

Autor: Brandt, F., Ullrich, M., Wodtke, J., Kopka, K., Bachmann, M., Löser, R., Pietzsch, J., Pietzsch, H.-J., Wodtke, R.

Publikováno v: Journal of Medicinal Chemistry 66(2023)1, 516-537

The applicability of radioligands for targeted endoradionuclide therapy is limited due to radiation-induced deleterious effects to healthy tissues. This applies in particular to the kidneys as primary organs of elimination, which requires dosimetric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::110badd7cbb20b44db72f835a3dd2e8e
https://www.hzdr.de/publications/Publ-35120-1

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Data to 'Application of a fluorescence anisotropy-based assay to quantify transglutaminase 2 activity in cell lysates'

Autor: Hauser, S., Sommerfeld, P., Wodtke, J., Hauser, C., Schlitterlau, P., Pietzsch, J., Löser, R., Pietsch, M., Wodtke, R.

Publikováno v: Publication date: 2022-04-13 Closed accessDOI: 10.14278/rodare.1537Versions: 10.14278/rodare.1538

Primärdaten zum FA-Assay, activity-based ELISA und ELISA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::3d183b1824d7a7b56d57ba28216f5d6f
https://www.hzdr.de/publications/Publ-34539-1

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Development of an 18F-labelled irreversible inhibitor of transglutaminase 2 as radiometric tool for quantitative expression profiling in cells and tissues

Autor: Wodtke, R., Wodtke, J., Hauser, S., Laube, M., Bauer, D., Rothe, R., Neuber, C., Pietsch, M., Kopka, K., Pietzsch, J., Löser, R.

Publikováno v: Journal of Medicinal Chemistry 64(2021)6, 3462-3478

The transamidase activity of transglutaminase 2 (TGase 2) is considered to be important for several pathophysiological processes including fibrotic and neoplastic tissue growth, whereas in healthy cells this enzymatic function is predominantly latent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::f4b7d673ed2e98320ef7c4a6fdced99e
https://www.hzdr.de/publications/Publ-32383-1

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Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging

Autor: Kritee, P., Neuber, C., Zarschler, K., Wodtke, J., Meister, S., Rainer, H., Pietzsch, J., Stephan, H.

Publikováno v: Small 16(2020)7, 1905013

Active tumor targeting involves the decoration of nanomaterials (NM) with oncotropic vector biomolecules that selectively recognize certain antigens on malignant cells or in the tumor microenvironment. This strategy can facilitate intracellular uptak

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::876f348d2faca907a958d4c04ff4cc54
https://www.hzdr.de/publications/Publ-30029-1

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Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide

Autor: Löser, R., Bader, M., Kuchar, M., Wodtke, R., Lenk, J., Wodtke, J., Kuhne, K., Bergmann, R., Haase-Kohn, C., Urbanová, M., Steinbach, J., Pietzsch, J.

Publikováno v: Amino Acids 51(2019)2, 219-244

The cell surface receptor claudin-4 (Cld-4) is upregulated in various tumours and represents an important emerging target for both diagnosis and treatment of solid tumors of epithelial origin. The C-terminal fragment of the Clostridium perfringens en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4577::fc2792b74360d9704b72eb1f53f95177
https://www.hzdr.de/publications/Publ-27932-1

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Akademický článek

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cDNA-Arrays

Autor: Sellckau R, Wodtke J, Kaiser E, G. Delling, C. Gentzsch, Plutat J

Publikováno v: Der Pathologe. 23:373-378

FACTS Aseptic loosening of hip arthroplasties are the main reason for revision operations. Basic research indicates a significant relevance of the interface membrane formed between the implant an the surrounding bone. Their cellular composition and t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4043823017f51476b98c78f2ffa0c27b
https://doi.org/10.1007/s00292-002-0556-y

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Analysis and results of 282 one stage exchange procedures for periprosthetic infection of the hip and knee

Autor: Wodtke, J, Jonen, V, Briem, D

Publikováno v: Deutscher Kongress für Orthopädie und Unfallchirurgie; 74. Jahrestagung der Deutschen Gesellschaft für Unfallchirurgie, 96. Tagung der Deutschen Gesellschaft für Orthopädie und Orthopädische Chirurgie, 51. Tagung des Berufsverbandes der Fachärzte für Orthopädie; 20101026-20101029; Berlin; DOCIN21-1111 /20101021/

Objective: One and two stage exchange procedures are acknowledged as gold standard for revision surgery in periprosthetic infection. The one stage concept seems to offer considerable benefits, especially with regard to “quality of life in surgery�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf649e9ce168a52bed88f8f340742235

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