Zobrazeno 1 - 10
of 287
pro vyhledávání: '"Wnts"'
Autor:
Sweta Parab, Olivia A Card, Qiyu Chen, Michelle America, Luke D Buck, Rachael E Quick, William F Horrigan, Gil Levkowitz, Benoit Vanhollebeke, Ryota L Matsuoka
Publikováno v:
eLife, Vol 12 (2023)
Fenestrated and blood-brain barrier (BBB)-forming endothelial cells constitute major brain capillaries, and this vascular heterogeneity is crucial for region-specific neural function and brain homeostasis. How these capillary types emerge in a brain
Externí odkaz:
https://doaj.org/article/62c0001578584539bd3fbebb88f27cca
Akademický článek
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Akademický článek
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Publikováno v:
Ecotoxicology and Environmental Safety, Vol 224, Iss , Pp 112667- (2021)
Cadmium is a severe environmental pollutant that mainly targets kidney and causes kidney disease in the end. However, the mechanism of cadmium-induced kidney disease is still unclear. In this study, we treated SD rats, kidney epithelial or fibroblast
Externí odkaz:
https://doaj.org/article/814021801ec74fe0a5bc6dc4ddb7d501
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Wnt signaling plays a critical role in bone formation, homeostasis, and injury repair. Multiple cell types in bone have been proposed to produce the Wnts required for these processes. The specific role of Wnts produced from cells of hematopoietic ori
Externí odkaz:
https://doaj.org/article/0dd04496b2ff4ec69a07d1b3dd5d7957
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Colorectal cancer (CRC) is the fourth leading cause of cancer death worldwide, and constitutive activation of the Wnt signaling pathway is universal in most CRC cases. Wnt ligands (Wnts) are secreted glycoproteins and fundamentally essential for the
Externí odkaz:
https://doaj.org/article/f3abd1fe045442c2ab675c7d896e6039
Autor:
Masaharu Takamori
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Myasthenia gravis (MG) is a disease of the postsynaptic neuromuscular junction (NMJ) where nicotinic acetylcholine (ACh) receptors (AChRs) are targeted by autoantibodies. Search for other pathogenic antigens has detected the antibodies against muscle
Externí odkaz:
https://doaj.org/article/7a768f968b1041229793b338e4365237
Publikováno v:
Cancer Management and Research, Vol Volume 10, Pp 1619-1626 (2018)
Ayesha Sohail,1 Lubna Sherin,2 Saad I Butt,1 Sana Javed,1 Zhiwu Li,3,4 Sohail Iqbal,5 O Anwar Be’g6 1Department of Mathematics, Comsats Institute of Information Technology, Lahore, Pakistan; 2Department of Chemistry, Comsats Institute of Informatio
Externí odkaz:
https://doaj.org/article/2adb3d46a38a4b36a02e99c129db86c0
Autor:
Serena Maggio, Paola Ceccaroli, Emanuela Polidori, Andrea Cioccoloni, Vilberto Stocchi, Michele Guescini
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2804 (2019)
Neuromuscular junction (NMJ) formation involves morphological changes both in motor terminals and muscle membrane. The molecular mechanisms leading to NMJ formation and maintenance have not yet been fully elucidated. During the last decade, it has be
Externí odkaz:
https://doaj.org/article/d9a5508a7c154899bcc39ddb489ec21a
Autor:
Naijun Miao, Fan Yin, Wei Zhang, Jingyao Li, Peiqing Zheng, Limin Lu, Xiaoxia Wang, Jun Liu, Z. Zhou, Li Zhou, Dan Xu, Panpan Chen, Jiayun Ni, Hongyan Xie, Yanzhe Wang, Qian Cheng
Publikováno v:
Journal of Cellular and Molecular Medicine
The activation of Wnt/β‐catenin pathway plays a pivotal role in promoting renal fibrosis. The activation of Wnt/β‐catenin pathway relies on the binding of Wnts to Frizzled receptors on cell membrane. However, the factor regulating Wnts producti