Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate

Autor: Arpan Parichha, Varun Suresh, Mallika Chatterjee, Aditya Kshirsagar, Lihi Ben-Reuven, Tsviya Olender, M. Mark Taketo, Velena Radosevic, Mihaela Bobic-Rasonja, Sara Trnski, Michael J. Holtzman, Nataša Jovanov-Milosevic, Orly Reiner, Shubha Tole

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)

The choroid plexus secretes cerebrospinal fluid and is critical for the development and function of the brain. In the telencephalon, the choroid plexus epithelium arises from the Wnt- expressing cortical hem. Canonical Wnt signaling pathway molecules

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78188af730de0afd2ce5c5adc776ba8f
https://doi.org/10.1038/s41467-021-27602-z

Key Genes of Lipid Metabolism and WNT-Signaling Are Downregulated in Subcutaneous Adipose Tissue with Moderate Weight Loss

Autor: Tilman Kühn, Mirja Grafetstätter, Ruth Schübel, Rudolf Kaaks, Theron Johnson, Judith Greimel, Disorn Sookthai, Mario Kratz, Cornelia M. Ulrich, Romy Kirsten

Publikováno v: Nutrients
Volume 11
Issue 3
Nutrients, Vol 11, Iss 3, p 639 (2019)
Schübel, R, Sookthai, D, Greimel, J, Johnson, T S, Grafetstätter, M E, Kirsten, R, Kratz, M, Ulrich, C M, Kaaks, R & Kühn, T 2019, ' Key Genes of Lipid Metabolism and WNT-Signaling Are Downregulated in Subcutaneous Adipose Tissue with Moderate Weight Loss ', Nutrients, vol. 11, no. 3 . https://doi.org/10.3390/nu11030639

Smaller cross-sectional studies and bariatric surgery trials suggest that weight loss may change the expression of genes in adipose tissue that have been implicated in the development of metabolic diseases, but well-powered intervention trials are la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f530736e758efe3b282b00b85d3269d
http://europepmc.org/articles/PMC6471921

Differential regulation of the Wnt/β-catenin pathway by hepatitis C virus recombinants expressing core from various genotypes

Autor: Annette Martin, Brigitte Blumen, Stephanie Aicher, Eliane F. Meurs, Penelope Mavromara, Athanasios Kakkanas, Lisette Cohen, Richard Njouom, Gabriela Oprişan

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2018, 8 (1), pp.11185. ⟨10.1038/s41598-018-29078-2⟩
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, 2018, 8 (1), pp.11185. ⟨10.1038/s41598-018-29078-2⟩

Clinical studies have suggested association of some hepatitis C virus (HCV) subtypes or isolates with progression toward hepatocellular carcinoma (HCC). HCV core protein has been reported to interfere with host Wnt/β-catenin pathway, a cell fate-det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc44ef9a207518b82f7ac0d08a16917c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02896787/document

Wnt / β-Catenin-Signalweg in Fälle von hepatozellulären Karzinomen aus Kolumbien

Autor: Rocio Lopez, Pierre Hainaut, Iris Suarez M, Germán Osorio, Pascal Pineau, Diego Uribe, Sergio Hoyos, Juan Camilo Pérez, Maria-C Navas, Carlos Mario Jaramillo

Publikováno v: Annals of hepatology : official journal of the Mexican Association of Hepatology
Annals of hepatology : official journal of the Mexican Association of Hepatology, Elsevier, 2015, 14 (1), pp.64-74. ⟨10.1016/S1665-2681(19)30802-6⟩
Annals of Hepatology, Vol 14, Iss 1, Pp 64-74 (2015)
Annals of hepatology : official journal of the Mexican Association of Hepatology, 2015, 14 (1), pp.64-74. ⟨10.1016/S1665-2681(19)30802-6⟩

International audience; Background and aim. Hepatocellular carcinoma (HCC) is the most common primary liver cancer diagnosed worldwide. Deregulation of Wnt/β-catenin pathway has been associated with the development of HCC in a substantial number of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafa6f788d30315f561f53249035eae5
https://doi.org/10.1016/s1665-2681(19)30802-6

Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus

Autor: Anna Griego, Francesco Aulicino, Antonio del Sol, Aniello Cerrato, Maria Pia Cosma, Gökhan Ertaylan, Anchel de Jaime-Soguero, Frederic Lluis, Aravind Tallam

Publikováno v: PLoS Genetics, Vol 13, Iss 3, p e1006682 (2017)
PLOS genetics (Online) 13 (2017). doi:10.1371/journal.pgen.1006682
info:cnr-pdr/source/autori:De Jaime-Soguero A.; Aulicino F.; Ertaylan G.; Griego A.; Cerrato A.; Tallam A.; del Sol A.; Cosma M.P.; Lluis F./titolo:Wnt%2FTcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4%2FArf locus/doi:10.1371%2Fjournal.pgen.1006682/rivista:PLOS genetics (Online)/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:13
PLoS Genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
Plos Genetics, 13(3):e1006682. Public Library of Science
De Jaime-Soguero, A, Aulicino, F, Ertaylan, G, Griego, A, Cerrato, A, Tallam, A, Del Sol, A, Cosma, M P & Lluis, F 2017, ' Wnt/Tcf1 pathway restricts embryonic stem cell cycle through activation of the Ink4/Arf locus ', PLoS Genetics, vol. 13, no. 3, e1006682 . https://doi.org/10.1371/journal.pgen.1006682

Understanding the mechanisms regulating cell cycle, proliferation and potency of pluripotent stem cells guarantees their safe use in the clinic. Embryonic stem cells (ESCs) present a fast cell cycle with a short G1 phase. This is due to the lack of e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0baf0be0d381ed144c662e251481d377
https://lirias.kuleuven.be/handle/123456789/629757